Psoriasis + KPV

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We have KPV on the way, I'm hoping it helps my skin issues. Let me know if you hear anything.

Maybe mine is psoriasis? I honestly don't know. My face just gets crusty sometimes and the only thing for it is religious moisturization. Blowdrying and ketoconazole shampoo fixed the problem at the scalp, but my face still gets flaky sometimes.

I really don't like it. It looks very unbecoming and ruins my self esteem when I let it get bad.
 
SakeSan said:
Glad I saw this post

My RS is on low dose Reta and saw modest impact on scalp psoriasis 3 months in. In 4th month, added klow, went through a vial. Skin got better and saw modest progress again. Started 1mg kpv mixed with 2.5mg GhkCU last 2 weeks and the flares just stopped completely. I’m going to run this for another week before lowering the dose.

Interested in sourcing TA1 as well, trying to find it in a us warehouse
Added TA1 and Ss31 for 2 weeks, 1 month ago - no flares since then. Paused all peps except Reta.

AI generated Strategy: Why these two?

• TA1 (Thymosin Alpha-1): This is the "peacekeeper." Psoriasis is a failure of T-regulatory (Treg) cells. TA1 helps the body produce more Tregs, which tell the aggressive T-cells to stop attacking the scalp. This is exactly what she needs to stop the "rebound itch."

• SS-31 (Elamipretide): Even at a low 2mg dose, SS-31 stabilizes the mitochondria in her skin cells. This reduces the "danger signals" (ROS) that keep the immune system in a state of alarm. It also protects her cells from the high metabolic demand of the Retatrutide.
 
olehandro said:
I have psoriasis of the palms. I injected KVP subcutaneously 500mcg per day. Everything got worse. The itching is unbearable. and the redness and peeling got worse.

So after a week I stopped.

Then I tried mixing KVP with my hand cream. (2 mg/2 grams of cream).

this also did not help.

All that helped me improve the situation was an infrared lamp every 2 days. I applied it for 3 minutes.
Uv light works wonders for psoriasis! Tanning bed once a week in winter. Lay out by the pool in the summer.
 
minipepbeast said:
Uv light works wonders for psoriasis! Tanning bed once a week in winter. Lay out by the pool in the summer.
This. And if you don't have access to the sun or a tanning bed, you can get yourself a UV-B light bulb for $10. It's called a lizard light because it's intended for reptile enclosures. Works great for spot-treating. Make sure it's UV-B, not UV-A.
 
I guess I'm lucky. I get some pretty big,flaky patches on my knees and elbows that I've had pretty consistently since I got run down in the last couple of years. I remember it being worse when I was a kid and having tar stuff I had to put in my bath. I know it's a combo of psoriasis and eczema but not much more. Thank you all again for your interesting discussion.
 
AYarter said:
Hey all,

I've has psoriasis my whole life, and tirz is keeping it at bay with the clobetasol cream that had stopped working years ago,. I also have inverse + nail psoriasis and am interested in using KPV to keep it at bay. I was interested in KLOW but I do not have a tolerance for insomnia, as tirz is already wrecking my life with it. I am also interested in TA1.

What are your thoughts on these? Have you used KPV as a lotion or in the more traditional way? What has been your experience?
Oh gosh. I m so sorry. I have no clue about KPV but have you already tried biologics?
 
PeppyPopper said:
I have had psoriasis over 80% of my body at times. I've been on Methotrexate and done the UV therapy, used every steroid cream possible and ironically have had the best results so far with Enstilar foam. However, since starting Reta the itching is driving me crazy again. I refuse to give up the Reta as its working so have ordered KPV, but 8f anyone out there has had better results with another peptide I would love to hear about it. 🙂
I am actually going to give VIP a run next week for my PsA. I will give it an 8 week run, but can keep you posted, if you would like!
 
PeppyPopper said:
I have had psoriasis over 80% of my body at times. I've been on Methotrexate and done the UV therapy, used every steroid cream possible and ironically have had the best results so far with Enstilar foam. However, since starting Reta the itching is driving me crazy again. I refuse to give up the Reta as its working so have ordered KPV, but 8f anyone out there has had better results with another peptide I would love to hear about it.

You have no idea how much I would appreciate that. Thank you. 🩷
Yes following for this also ! Damn dry and itchy skin 😩
 
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