Peptides won't reconstitute

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Rolltide61

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I've had some peptides from Nexa (Reta and Tirz) that have been in the fridge a couple months. Maybe 3 -4 months. They will not reconstitute. I've even let them sit out for an hour. First couple bottles out of kit were fine. Am I doing something wrong?
 
I have peps that been in the freezer for years and never ran into that? Seems strange, and being in the fridge should not affect them for even years
 
You let the vial go room temperature? And then it can take 20 minutes to fully dissolve....nexa doesn't go without issues either, noones immune.
 
If your bacteriostatic water was also refrigerated, it will take a few hours for everything to get to room temperature (ish). Once there, shaking the reconstituted vials should dissolve the lyophilized peptides.

The unopened, unreconned vials are better left in the freezer (vs refrigerator), then brought to room temp when you need to reconstitute them.
 
indolent said:
If your bacteriostatic water was also refrigerated, it will take a few hours for everything to get to room temperature (ish). Once there, shaking the reconstituted vials should dissolve the lyophilized peptides.

The unopened, unreconned vials are better left in the freezer (vs refrigerator), then brought to room temp when you need to reconstitute them.
I thought shaking was a no-no. I did just now shake it up (been room temp about 8 hours now) and it's still clumped as heck.
 
Where is your source for bac water?
 
CNCCurrency said:
Maybe its your bac water?
I thought about that but the same bottle worked just fine w/ my wife's Glow. The bottle of Glow is a diff vendor and just came in Friday afternoon.
 
The ph or some additive in the bac water might be causing it. The fact that 2 different peptides won't dissolve makes me suspect the water. Different peptides have different ph ranges for successful recon.
 
swimmer said:
The ph or some additive in the bac water might be causing it. The fact that 2 different peptides won't dissolve makes me suspect the water. Different peptides have different ph ranges for successful recon.
Even if my wife's Glow worked fine? Do I chuck the bottle or all of 6 of them?
 
Rolltide61 said:
I've had some peptides from Nexa (Reta and Tirz) that have been in the fridge a couple months. Maybe 3 -4 months. They will not reconstitute. I've even let them sit out for an hour. First couple bottles out of kit were fine. Am I doing something wrong?
What temp you stored?

Before reconstitute, how did the liophilized looked? Same look as the 1st day?

Did they hold the vaccum? Did you checked that when you reconstitute?
 
Lyophilized said:
What temp you stored?

Before reconstitute, how did the liophilized looked? Same look as the 1st day?

Did they hold the vaccum? Did you checked that when you reconstitute?
Temp in fridge is 38. Powder was still sugar white.
 
Rolltide61 said:
Even if my wife's Glow worked fine? Do I chuck the bottle or all of 6 of them?
I would buy some Hospira and see if that will successfully dissolve the peptides. Tossing water is much cheaper than tossing un-disolved peptides.
 
Never use vendor/Amazon bac. It's not tested regularly, and some have contained zero alcohol, wrong pH, etc/ Basically it could be toilet water. Use pharma grade bac only...Hospira.
 
Rolltide61 said:
I thought shaking was a no-no. I did just now shake it up (been room temp about 8 hours now) and it's still clumped as heck.
Janoshik founder Peter Magic says no problem with shaking GLP peptides when reconstituting. It's a myth.
 
Rolltide61 said:
I've had some peptides from Nexa (Reta and Tirz) that have been in the fridge a couple months. Maybe 3 -4 months. They will not reconstitute. I've even let them sit out for an hour. First couple bottles out of kit were fine. Am I doing something wrong?
I have used a two inch needle to break up a clump with success in a nad+ vial
 
Nailedit said:
Janoshik founder Peter Magic says no problem with shaking GLP peptides when reconstituting. It's a myth.
Don't take everything he says as gospel.
 
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