Of the big 3......

[jwilson1828]

50lbs in 5 months with Reta? Wow that is crazy! Any side effects? Great story-thanks for that!

Nothing other than the expected slower digestion and slower emptying. I have been at the same weight for the past 10 days or so, but I am not overly concerned as my hunger/satiety hasn't really changed. I just keep plugging away. My wife, after my lack of sides, decided to join in the research as well. She is down from 215 to about 180 and never got higher than 6mg. We are discussing lowering her dose and she could focus on recomp if she wants, but she doesn't really want to weight much less since she is just under 5'10". Especially since she was averaging a couple pounds per week.

 

[HereKittyKitty]

I won't underestimate the power of retatrutide. I reached me goal and switched to retatrutide. My appetite went up but I kept losing weight on maintenance dose. Burns the fat off for me regardless of appetite.

That's amazing. What is it about Reta that gets the fat burning? Or are you much more fit now and the muscle is doing its work to increase RMR?

 

[QueenMuntha]

Reta better at sparing muscle and combatting insulin resistance. Tirz better for killing food noise. Sema best for inducing nausea.

Facts, my man, Facts.

 

[MFGamesta]

I am eating a little better but I believe it's the GIP and Glucagon part of the retatrutide. My exercise habits haven't really changed. Note that I only wanted to get down from 202 to 170.

 

[Zydeceltico]

I won't underestimate the power of retatrutide. I reached me goal and switched to retatrutide. My appetite went up but I kept losing weight on maintenance dose. Burns the fat off for me regardless of appetite.

When you switched to reta, what dose did you start with?

 

[Speak_Easy]

Ok. So i want experiences.

I have tried sema. Lost 46lbs. Have stalled. Not sure if i want to add cagri or just go to Tirz. Even reta.

I would love to all yout experiences with the 3. I've hears reta is the best, but tirz is the best at appetite suppression. I feel thats what I need since im a bored snacker. So how is reta better? Hell, I even snack when im full!

Not sure the route to take

Suggestions?

I have moved from Tirz to Reta. The Tirz does have very strong appetite suppression (stronger than Reta), however it also came ROARING back when I lowered my Tirz dose to start Reta. I wanted to be on Reta because I think it's a more balanced med, and has reported ancillary benefits (anti inflammatory, heart health and others) that aren't present in Tirz. If it were me, I'd switch to Reta and slowly titrate up. Be aware that Reta seems to take longer to work when you've been on another GLP1, it can take 4 weeks to achieve steady state blood concentration, which is when you should start to feel/see results. Of course everyone is different, and it could work right away at lower doses...so "mileage may vary".

 

[MFGamesta]

When you switched to reta, what dose did you start with?

While I was on Zepbound, I stayed on weekly 2.5mg the whole 3 months I went from 202 to 170 (my goal). 13% body fat according to InBody at gym. I then went cold-turkey to reta at weekly 2mg and gained about 5 lbs in 2 weeks and upped it to 4mg after 4 weeks.

Appetite didn't change and I started losing weight agin. I'm definitely eating more after the switch but the reta doesn't seem to care. Something with the 4mg told my body to burn more and I do have more energy as well. I can barely keep up and may drop back down to 3 or 2mg weekly.

I was already on testosterone, CJC-1297/Ipamorelin, and GLOW during the whole Zepbound phase and still use these.

I eat one full meal a day that focuses on protein and veggies but there a carbs too...pasta, rice, whatever sugars are in the dishes. And I snack on things like meat sticks and protein shakes once or twice a day. Not the healthiest diet but it's not ben and jerry's every night.

I do play tennis 3-5 times a week and run/lift 3-5 times a week so I'm very active.

The only reason I went on this diet was because at 60 and being 200lbs, it affected my tennis mobility. Not to mention the 27% body fat and approaching insulin resistance pretty quickly.

 

[Gr33dyOctopus]

You can stack them all, lol.

I do!!!

 

[Zydeceltico]

While I was on Zepbound, I stayed on weekly 2.5mg the whole 3 months I went from 202 to 170 (my goal). 13% body fat according to InBody at gym. I then went cold-turkey to reta at weekly 2mg and gained about 5 lbs in 2 weeks and upped it to 4mg after 4 weeks.

Appetite didn't change and I started losing weight agin. I'm definitely eating more after the switch but the reta doesn't seem to care. Something with the 4mg told my body to burn more and I do have more energy as well. I can barely keep up and may drop back down to 3 or 2mg weekly.

I was already on testosterone, CJC-1297/Ipamorelin, and GLOW during the whole Zepbound phase and still use these.

I eat one full meal a day that focuses on protein and veggies but there a carbs too...pasta, rice, whatever sugars are in the dishes. And I snack on things like meat sticks and protein shakes once or twice a day. Not the healthiest diet but it's not ben and jerry's every night.

I do play tennis 3-5 times a week and run/lift 3-5 times a week so I'm very active.

The only reason I went on this diet was because at 60 and being 200lbs, it affected my tennis mobility. Not to mention the 27% body fat and approaching insulin resistance pretty quickly.

Thank you for the detailed response. Exactly what I needed. My story is similar and investingating the idea of reta for similar reasons. I've been stacking survo on tirz for months and have been at gw for 3 months and am wondering if I can get away with a single injection of reta per week rather than the double of tirz and survo and also if the energy level might be different although my tirz/survo stack has delivered very, very well for me. I also use BPC, TB, & KPV. Just seperately. Also CJC/Ipa. Also for strength training and cardio. I'm 62 and went from 240 to my current 185 since last June. Takes dedication and consistency as I am sure you know. Totally worth it. Congrats!

 

[RoadRash]

Ok. So i want experiences.

I have tried sema. Lost 46lbs. Have stalled. Not sure if i want to add cagri or just go to Tirz. Even reta.

I would love to all yout experiences with the 3. I've hears reta is the best, but tirz is the best at appetite suppression. I feel thats what I need since im a bored snacker. So how is reta better? Hell, I even snack when im full!

Not sure the route to take

Suggestions?

I have found Reta to be really good at stopping food noise and although it doesn't entirely shut down the ability to eat, I'm not sure total food suppression is a good goal. I started at 2mg of Reta weekly, then titrated to 4mg and now the food chatter is gone but I can still eat when I need to. What I can't do is stuff myself, I have no interest in crappy food, and I want to be able to eat good, clean food and hit my macros so that I can maintain muscle mass as best I can. This is what Reta does perfectly.

I think if you get to your therapeutic dose with reta and you are exercising and eating clean, it's the best of all possible worlds. I am convinced having used semaglutide and tirzepitide that Reta is the healthiest choice. But that's just me!

 

[JoonyO]

my tirz/survo stack has delivered very, very well for me.

Uh...if it ain't broke why "fix" it?

 

[Zydeceltico]

Uh...if it ain't broke why "fix" it?

Two reasons: 1) one injection per week instead of two & 2) curiosity & comparison

 

[dirtyharry]

You know with all the talk of Reta vs. Tirz for less muscle loss; I wonder how much of it has to do with the indivisuals diet. Like, if you eat the right amount of protein and change nothing about your workout routine, isnt it safe to assume you'll maintain the same amount of muslce regardless of which GLP you go with?

 

[latviantower]

You know with all the talk of Reta vs. Tirz for less muscle loss; I wonder how much of it has to do with the indivisuals diet. Like, if you eat the right amount of protein and change nothing about your workout routine, isnt it safe to assume you'll maintain the same amount of muslce regardless of which GLP you go with?

They’re finding there’s little to no difference in muscle sparing between reta and tirz:

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[dirtyharry]

They’re finding there’s little to no difference in muscle sparing between reta and tirz:

View attachment 16822

Appreciate the response. Yeah I had heard both sides but it seems this is the final verdict. Either way, I'm hoping with proper diet that muscle loss wont be an issue.

 

[leeann82]

Never tried sema. I did briefly try the pills, rybelsus for a couple months, rybelsus didn't really do much for me. Ive been on tirz now for 7 weeks tomorrow....this stuff is great. I was the type to snack all day long..almost hourly. A handful of this..hand full of that...etc. now I can barely even remember to eat, and often forget. Definitely no more snacking here. Started at 178, not at 147. 31 pounds down on my third shot of 5mg tomorrow. I love that im no longer thinking of food all day long. So much more space in my brain to think of other things.

Haven't tried reta, and wont likely, as im very happy with tirz.