New Reta Triumph 1 Results

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I was just commenting on the fact that participants in the 4mg group lost 19% of their starting weight in 80 weeks and participants in the placebo group lost 19.2% in 24 weeks. That's a big difference in time on the medication to achieve nearly the same results. Even if we adjust out the 2.2% loss that the placebo group lost during the first 80 weeks, it's still almost the same.

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I don't know about you, but if I had the choice to lose 50 pounds in 6 months versus 50 pounds in 1.5 years, I'd take the former rather than the later.

We have a lot of people in the forum asking for advice about what to do when they stall or plateau on these medications and less so people begging to slow down weight loss.

But, low and slow definitely works. Probably better for those in a less diseased state when they start treatment. I have a family member lose 50lbs on less then 2mg of tirzepatide over 9 months. But she didn't spend her entire life obese, and wouldn't have meet the clinical requirements to be on the meds in the first place.

Since you only have 10lbs to lose, my comments were definitely not directed towards you. Being on TRT, reta, and add in some tesa and your abs will be showing before you know it.
 

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Grogu said:
…And it's not the same 28%. The 12mg group lost 30.3% and the 4mg group lost 27.9% at 104 weeks. That's a difference of 2.4% or about 12 pounds difference in loss. That's not the same.

The exposure over time curve for the 4mg group and the 12mg group is widely different. A direct comparison of their likely maximum loss at 12mg isn’t fair 24 weeks vs 104 weeks.
 
cujet said:
Thanks, I read that but wrote the wrong thing. Corrected.

Totally understand. It's not like we had the actual study to look at, it was just from a press release. And this study is unlike a lot of the other glp-1 clincial trials, as far as the titration. It was a pretty cool research design.

BTW - I'm in PB County too, just in the southern part.
 
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