Nikki nik
GLP-1 Specialist

Perfect addition. I noticed my belly going down with the 2Peloma said:I see where what I wrote seemed confusing. I want to keep myself at 50 units of as long as possible. Figured Mots would be a good addition.

Perfect addition. I noticed my belly going down with the 2Peloma said:I see where what I wrote seemed confusing. I want to keep myself at 50 units of as long as possible. Figured Mots would be a good addition.


For some, they seem to experience ISR burn, I personally never have. If any at all it would be temporary at best. I did mix 10mg/1ml so had 2 doses in each vial, some say adding more BAC helps, others are concerned with PH. I might just be lucky or oblivious, a little sting goes away quickly on the occasion I had any at all.Peloma said:So the burn is a thing, eh?

Noticed a little sting that went away immenselyPeloma said:So the burn is a thing, eh?
I feel nothing with my QSC Mots-c mixed to take 5mg in 0.5 mL.Peloma said:So the burn is a thing, eh?


Curious: did you pin both doses in a day, or space them out? Either way (and I know it has been disproven, but), did you notice a degradation in effects on shot 2 when taken later?Skidude said:For some, they seem to experience ISR burn, I personally never have. If any at all it would be temporary at best. I did mix 10mg/1ml so had 2 doses in each vial, some say adding more BAC helps, others are concerned with PH. I might just be lucky or oblivious, a little sting goes away quickly on the occasion I had any at all.

the 10/1 I was referring to was just reconstitute mix, some might mix 1.5ml BAC.Peloma said:Curious: did you pin both doses in a day, or space them out? Either way (and I know it has been disproven, but), did you notice a degradation in effects on shot 2 when taken later?

Do you think I shouldn't go straight to Mots-c? On Tirz now. Should I start with ss, then move on to mots?Skidude said:the 10/1 I was referring to was just reconstitute mix, some might mix 1.5ml BAC.
I use simple math when reconstituting, if i want 1/3 total pep, i triple my desired BAC. in this case I want 1/2 pep so I doubled Bac. IE: 10MG vial = 2 doses no matter how much bac i add. 2 ml would be 1 ml per dose. 1 ml is .5ml per dose, and so on.
My protocol was 5mg 3x per week. I think the effect was more underlying than obvious, but I will be doing another cycle soon. I also did the SS-31 for first 30 days and took TMG.
My next protocol is likely going to be SS-31 morning, Mots evening.
Quantifying effects is challenging as there are many factors, not the least of which is the Tirz fatigue.
I do feel like there are benefits, and from what I have read, many that are just not feels.

I am not sure I understand the question. I used these for other reasons than Tirz so these are stacks/etc.Peloma said:Do you think I shouldn't go straight to Mots-c? On Tirz now.
quoted said:Using MOTS-C While Taking Tirzepatide
MOTS-C and Tirzepatide (GLP-1/GIP receptor agonist) can be used together, but some factors should be considered :
Potential Benefits of Combining MOTS-C and Tirzepatide:
Enhanced Fat Loss – Tirzepatide improves insulin sensitivity and reduces appetite, while MOTS-C enhances mitochondrial function and fat oxidation.
Improved Energy & Metabolism – MOTS-C helps with cellular energy production, which may counteract any fatigue from GLP-1 agonists.
Muscle Preservation – Tirzepatide can sometimes lead to lean mass loss, but MOTS-C supports muscle health and endurance.
Considerations & Precautions:
Potential Increased Insulin Sensitivity – Both compounds improve insulin sensitivity, so blood sugar levels should be monitored to prevent hypoglycemia.
Fatigue & Nausea Risk – GLP-1 drugs can cause nausea, while MOTS-C may briefly lead to fatigue. Start with lower doses if needed.
Dosing Timing – Some prefer using MOTS-C on non-Tirzepatide injection days to avoid overwhelming the system.
Suggested Dosing Strategy:
Tirzepatide: As prescribed (usually weekly).
MOTS-C: 5 mg 3x per week for 4-6 weeks , then taper or take a break.

Should ss preceed mots, or does it matter? I'm stacking with tirz.Skidude said:I am not sure I understand the question. I used these for other reasons than Tirz so these are stacks/etc.
This is what my girlfriend (AKA ChatGPT) has to say about this:



I use my Mots C for normal work days! 2.5 for 5 days a weekhotdog! said:So is the mots-c 3 x a week more for strength during workouts? I don't work out, I just want to combat the Tirz fatigue. Would once or twice weekly do that?

I've never pinned 5mg at once but I am this weekend in hopes of hitting the gymhotdog! said:So is the mots-c 3 x a week more for strength during workouts? I don't work out, I just want to combat the Tirz fatigue. Would once or twice weekly do that?

How are the feels at 2.5?Nikki nik said:I use my Mots C for normal work days! 2.5 for 5 days a week


Clean energy.... been cycling on and off for 6 months or more. Never really gone higher than 2.5 or 3mg in 1 days. I would love to try 5mg. Doing that when my new order arrivesPeloma said:How are the feels at 2.5?
