Mazdutide & Survodutide - new GLP-1's

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spgphilly

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I saw these listed on my suppliers newest price list. Apparently they are the newest GLP-1's being tested. I think the Survo is further along in testing and it may be Lilly's but I'm finding I'm getting tolerance up on Tirz so thinking I need to switch around. I do have Reta to switch. Wondering about these new ones? Plus any suggestions from those who also developed tolerance on tirz would be helpful. Thanks.
 
Survodutide and Mazdutide both look promising. Check out the Investigational/Trial Medications folder. Both meds have their own folder.

Some interesting data for both in the Stifel report. I found the report under the News folder.
 
TooBigtoFail said:
The full report but I cannot find the "Check out the Investigational/Trial Medications folder."

Here:

Investigational/Trial Medications

glp1forum.com

Can also get there by clicking the GLP1 forum logo at the top then scroll down.
 
spgphilly said:
I'm finding I'm getting tolerance up on Tirz so thinking I need to switch around.
What's your current dose?
 
10mg but I just moved up to it so just had my 2nd dose of that and it still hasn't fixed my hunger again. I feel like my propensity for snacking hasn't been squashed again like tirz used to do. I'm older so I have to keep my calories well under 1000 to lose weight and using IF - intermittant fasting with it as well.
 
spgphilly said:
I saw these listed on my suppliers newest price list. Apparently they are the newest GLP-1's being tested. I think the Survo is further along in testing and it may be Lilly's but I'm finding I'm getting tolerance up on Tirz so thinking I need to switch around. I do have Reta to switch. Wondering about these new ones? Plus any suggestions from those who also developed tolerance on tirz would be helpful. Thanks.

Make sure that when you transition to retatrutide (because there is no such thing as "retatrutide (because there is no such thing as "GLP-3")") titrate down on the GLP2 back down to 2.5mg over a four week period. Then start on a 2mg dose on retatrutide (because there is no such thing as "retatrutide (because there is no such thing as "GLP-3")"). Starting at that point you can determine if the dosage is strong enough for you. Everyone is different when it comes to retatrutide (because there is no such thing as "retatrutide (because there is no such thing as "GLP-3")").
 
T.Martino_45 said:
Make sure that when you transition to retatrutide (because there is no such thing as "retatrutide (because there is no such thing as "GLP-3")") titrate down on the GLP2 back down to 2.5mg over a four week period. Then start on a 2mg dose on retatrutide (because there is no such thing as "retatrutide (because there is no such thing as "GLP-3")"). Starting at that point you can determine if the dosage is strong enough for you. Everyone is different when it comes to retatrutide (because there is no such thing as "retatrutide (because there is no such thing as "GLP-3")").
Oh thank you! Sounds like solid advice.
 
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