Maybe this can help with the sterility/endotoxin issue(s)

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dancs

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Not sure if this is allowed, but my only intention is to help all my friends and family here (peptide community) in any way I can!

Recently, many products we're receiving from some of the vendors are coming up with failed sterility/endotoxins.

I know this may not completely get rid of but at the very least mitigate the potential consequences of blindly trusting the vendor COA's and/or having faith in God that we'll make it after pinning ourselves 5+ times day 🤣 (always trust in God! 🙂 ). Or rather than waiting on a group of others who bought the same product with the same batch numbers (not all vendors have batch numbers 😞) who are also willing to group test through Janoshik which will take 2-4 weeks for result(s), or pay for the testing yourself $250-$750 depending on which and how many types of testing you want per that vial/product.... That's crazy talk. Now, this won't clear up the purity and actual compound in the vial/product but we can at least have a better "peace of mind" knowing we can take initiative and take our own precautions before pinning.

If you're looking for Hospira Bac Water which is always recommended for foreign products and has a decent price (frequent sales) -

Bacteriostatic Water

www.bacteriostaticwater.com

If you're looking for sterile, medical grade vials that are relatively cheaper (don't trust Amazon), then here -

Sterile Empty Glass Vials 10 mL (Medical Vials)

Buy empty vials 10 ml & sterile vials used for mixing drugs & laboratory testing. Find top glass vials, medical vials & laboratory vials at low bulk prices.

www.mountainside-medical.com

If you're looking for filters that can get rid of most or all endotoxins and you have the budget -

https://www.vwr.com/us/en/product/7605181/acrodisc-units-with-mustang-e-membrane-cytiva-formerly-pall-lab?r=1

Keep in mind that these filters can potentially take out all endotoxins, BUT they do not take out other bacteria (lack of proper sterilization.)

If you're looking for filters that can do both sterilize AND get rid of endotoxins (NOT all endos but some) AND are on a tighter budget like me -

Syringe Filter, Acrodisc, Posidyne, 25 mm, 0.20 µm, sterile, 50 pc/PAK

www.analytics-shop.com

Here's a tutorial on how to sterilize your products -

View: https://www.youtube.com/watch?v=o7EUN3FGzPs

This also tells you what to buy to get started with the process including buying filters to sterilize the product (sterilization and endotoxins are 2 separate issues).

I double checked all of these websites validity and they're all good to go. Again, these MAY NOT GET RID OF ALL STERILIZATION AND ENDOTOXIN ISSUES, but they can definitely help tremendously to the point where rather than relying on group testing, relying on spending thousands for testing on vial(s) and waiting weeks/months for results, doing this proactively can cause less stress, less time, and hopefully more happiness (pinning faster and earlier for expected results 🥹.)

I understand that these vendors still need to take accountability and need to change their way of handling products and I agree that they should all be as transparent as possible, willing to cooperate with their patrons whether through refunds, reships and/or paying for the failed test results, but while we wait for them to man up (some have, others haven't, yet), we can do this on our own.
 
My understanding is that it's easier to filter out the bacteria than the endotoxins. The bacteria are larger and less likely to pass through the filter. 🤔
 
FartfulCodger said:
My understanding is that it's easier to filter out the bacteria than the endotoxins. The bacteria are larger and less likely to pass through the filter. 🤔
Oh shoot, thanks for the reminder! Will add that on there too! And yes, you can buy standard filters on Amazon if you want to help sterilize the products, but endotoxins are a completely different issue. Standard filters cannot take them out. Very specific acrodisc filters are used to either partially remove or completely remove endotoxins.
 
dancs said:
Cytiva

www.cytivalifesciences.com
Only $301 each. And I still don't see how it filters endos that are less than .2u. It does say reduce though, not eliminate.
 
Chili777 said:
Only $301 each. And I still don't see how it filters endos that are less than .2u. It does say reduce though, not eliminate.
Yes, if it's not in the most ideal conditions and preparations, I don't think we could ever completely get rid of endotoxins. However, given with what we do have, we can definitely get rid of some --- given the current measurements and the issues pertaining to each vendor including Uther and their extreme numbers of toxin, we could mitigate the potential damages caused to our bodies.

I also posted a link for a cheaper alternative which contains a 50 pack for $250 ---- these filters reduce the amount of endos and helps sterilize whatever product is inside those vial(s).
 
dancs said:
Yes, if it's not in the most ideal conditions and preparations, I don't think we could ever completely get rid of endotoxins. However, given with what we do have, we can definitely get rid of some --- given the current measurements and the issues pertaining to each vendor including Uther and their extreme numbers of toxin, we could mitigate the potential damages caused to our bodies.

I also posted a link for a cheaper alternative which contains a 50 pack for $250 ---- these filters reduce the amount of endos and helps sterilize whatever product is inside those vial(s).
Rather than spending that kind of money on filters, I'd rather do the calculation as to how much endotoxin I'd be exposed to, per dose and frequency, and make my decision from there. I filter everything anyway for the rest of it. I also think we need to hold vendors to higher endo standards, like the recent turnaround with Jeep. Anything <100EU per vial, I'm not that worried about with a weekly pin, again based on total exposure, and that's the range we find in most of the positive endo tests.
 
dancs said:
Not sure if this is allowed, but my only intention is to help all my friends and family here (peptide community) in any way I can!

Recently, many products we're receiving from some of the vendors are coming up with failed sterility/endotoxins.

I know this may not completely get rid of but at the very least mitigate the potential consequences of blindly trusting the vendor COA's and/or having faith in God that we'll make it after pinning ourselves 5+ times day 🤣 (always trust in God! 🙂 ). Or rather than waiting on a group of others who bought the same product with the same batch numbers (not all vendors have batch numbers 😞) who are also willing to group test through Janoshik which will take 2-4 weeks for result(s), or pay for the testing yourself $250-$750 depending on which and how many types of testing you want per that vial/product.... That's crazy talk. Now, this won't clear up the purity and actual compound in the vial/product but we can at least have a better "peace of mind" knowing we can take initiative and take our own precautions before pinning.

If you're looking for Hospira Bac Water which is always recommended for foreign products and has a decent price (frequent sales) -

Bacteriostatic Water

www.bacteriostaticwater.com

If you're looking for sterile, medical grade vials that are relatively cheaper (don't trust Amazon), then here -

Sterile Empty Glass Vials 10 mL (Medical Vials)

Buy empty vials 10 ml & sterile vials used for mixing drugs & laboratory testing. Find top glass vials, medical vials & laboratory vials at low bulk prices.

www.mountainside-medical.com

If you're looking for filters that can get rid of most or all endotoxins and you have the budget -

https://www.vwr.com/us/en/product/7605181/acrodisc-units-with-mustang-e-membrane-cytiva-formerly-pall-lab?r=1

Keep in mind that these filters can potentially take out all endotoxins, BUT they do not take out other bacteria (lack of proper sterilization.)

If you're looking for filters that can do both sterilize AND get rid of endotoxins (NOT all endos but some) AND are on a tighter budget like me -

Syringe Filter, Acrodisc, Posidyne, 25 mm, 0.20 µm, sterile, 50 pc/PAK

www.analytics-shop.com

Here's a tutorial on how to sterilize your products -

View: https://www.youtube.com/watch?v=o7EUN3FGzPs

This also tells you what to buy to get started with the process including buying filters to sterilize the product (sterilization and endotoxins are 2 separate issues).

I double checked all of these websites validity and they're all good to go. Again, these MAY NOT GET RID OF ALL STERILIZATION AND ENDOTOXIN ISSUES, but they can definitely help tremendously to the point where rather than relying on group testing, relying on spending thousands for testing on vial(s) and waiting weeks/months for results, doing this proactively can cause less stress, less time, and hopefully more happiness (pinning faster and earlier for expected results 🥹.)

I understand that these vendors still need to take accountability and need to change their way of handling products and I agree that they should all be as transparent as possible, willing to cooperate with their patrons whether through refunds, reships and/or paying for the failed test results, but while we wait for them to man up (some have, others haven't, yet), we can do this on our own.
Your endotoxin filter will also filter out the peptide.
 
Habibibi said:
Your endotoxin filter will also filter out the peptide.

I'm aware that any type of filtering will take out some of the compound, but I guess there's no way of precisely calculating just how much.... Either way, I thought that maybe those who don't want to get testing done due to financial burden, wait for group testing to be done, wait potentially a month for the test results to come through, that there's an alternative to all of this.

Chili777 said:
Rather than spending that kind of money on filters, I'd rather do the calculation as to how much endotoxin I'd be exposed to, per dose and frequency, and make my decision from there. I filter everything anyway for the rest of it. I also think we need to hold vendors to higher endo standards, like the recent turnaround with Jeep. Anything
 
dancs said:
I'm aware that any type of filtering will take out some of the compound, but I guess there's no way of precisely calculating just how much.... Either way, I thought that maybe those who don't want to get testing done due to financial burden, wait for group testing to be done, wait potentially a month for the test results to come through, that there's an alternative to all of this.

Ahh, JEEP. I thought I saw Uther had a similar issue with extremely high rates of toxins... Probably both and in reality, we should definitely assume the worst for all products.
It will take out most of the compound. The filter you posted doesn't rely on pore size but on charge to remove endotoxins. F ilter is positively charged. GLP1s are negatively charged. Most of the GLP1 will stay in the filter, along with endotoxins.
 
Habibibi said:
It will take out most of the compound. The filter you posted doesn't rely on pore size but on charge to remove endotoxins. F ilter is positively charged. GLP1s are negatively charged. Most of the GLP1 will stay in the filter, along with endotoxins.
Oh shoot.... 😞 😞 😞

Even the 50 pack for $250? 🥹
 
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