吉普车

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Danger1212 said:
I think some folks might be ok with the endos, but from what I’ve heard it’s the TAMC and TYVM fails (bacteria, and fungal) that draw the most concern.

Veterans, correct me if I am wrong.

Everyone needs to consult with their own health professionals
 
Hey, can you send me an invite to your group? I don’t have a DM here, but I do on Peppy with the same user name.
 
JoonyO said:
If, for instance, I'm filtering a 30mg vial with 3ml of BAC I will first recon the vial with only 2 or 2.5 BAC then filter that and use the remaining 1 or .5 BAC water necessary to reach a total of 3ml to "flush" any remaining pep left, from filtering, in the filter into the vial..I hope. Or at least that's my "strategery".
Mine too, usually into a cartridge, or split into two for klow80
 
I think the standard view tends to be assume nothing is steril and filter everything. If that's the view, then knowing something has failed shouldn't really matter. It hits different when you see it, but I feel like, if we are being consistsnt, it shouldn't matter. Endos look low to me. I don't think it would be as big a concern if Jeep hadn't failed endo spectacularly recently. Like I said, I think this is likely typical of what we have been using and we just haven't had the proof.
 
5byfive said:
I think the standard view tends to be assume nothing is steril and filter everything. If that's the view, then knowing something has failed shouldn't really matter. It hits different when you see it, but I feel like, if we are being consistsnt, it shouldn't matter. Endos look low to me. I don't think it would be as big a concern if Jeep hadn't failed endo spectacularly recently. Like I said, I think this is likely typical of what we have been using and we just haven't had the proof.
Yeah I hear you and I appreciate you guys saying it straight.

If the baseline is “assume nothing is sterile and filter everything,” then technically this doesn’t change much… it just hits different when you actually see a fail instead of assuming it in the background.

Endos didn’t really jump out to me either. I think a lot of the reaction is just timing after that recent mess, Same data, different feeling.

From what I’m hearing it’s sounding like this probably is what we’ve been using all along… We just didn’t have the results before.
 
Danger1212 said:
所以,TAMC 和 TYMV 指的是细菌和真菌污染吗?

过滤能去除这些吗?

我是个新手,什么都不懂,但很好奇:这种情况常见吗?危险性如何?
不再无菌意味着细菌微生物会滋生,内毒素会积聚,如果含量达到不安全的水平,可能会导致生病甚至败血性休克,而且据我所知,没有任何过滤方法可以去除内毒素。
 
QueenMuntha said:
有意思。这是吉普针对同一批次车辆的测试结果: https://verify.janoshik.com/tests/80925-R30_8YSG7F76GKG2

这让我很疑惑,为什么他们只公布了质量和纯度。

5byfive said:
我认为通常的观点是假设所有东西都不是绝对无菌的,然后对所有东西进行过滤。如果真是这样,那么知道某些东西失效了其实也无关紧要。亲眼看到失效的情况会有不同的感受,但我觉得,如果我们始终保持一致,那就应该没问题。

这确实很重要,TAMC 和 TYVM 检测不合格表明后加工过程卫生状况堪忧,敷衍了事。

高纯度产品通常来自廉价购入的劣质原料,这款产品虽然勉强合格,但按美国标准来看,是否达到药用级别仍存疑。

“足够好”的质量控制在美国会导致产品召回,工厂停产。
 
Retazempic said:
就我个人而言,如果有人愿意按成本价加运费出售这些套件,我非常乐意购买。
当然,检查完成后,费用也付清了,你就知道自己要面对什么了。

即使你正在进行筛选,仍然需要知道子宫内膜异位症的发生率。
 
Danger1212 said:
过滤能去除这些内容吗?
使用优质过滤器和 Hospira Bac,您可能永远不会知道有人对着打开的小瓶打喷嚏。 😆
 
RetCurious said:
使用优质过滤器和 Hospira Bac,您可能永远不会知道有人对着打开的小瓶打喷嚏。 😆

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RetCurious said:
使用优质过滤器和 Hospira Bac,您可能永远不会知道有人对着打开的小瓶打喷嚏。 😆
我知道你是在开玩笑,但你是说你会把 Hospira Bac recon 和过滤器用在你的 RS 上吗?
 
5byfive said:
我认为通常的观点是假设所有东西都不是无菌的,然后对所有东西进行过滤。如果真是这样,那么知道某个环节出了问题其实也无关紧要。亲眼看到问题出现时感觉肯定不一样,但我觉得,如果我们操作流程一致,应该就没什么问题。在我看来,内镜检查结果偏低。如果吉普车最近没有出现内镜检查的严重故障,我想这也不会引起这么大的担忧。就像我说的,我认为这很可能是我们一直以来使用的设备的一个典型情况,只是我们还没有证据而已。

我个人也是这么看的。使用

Bac水、冷藏、过滤,并在三个月内用完所有样品,这些都是我尽量控制无菌风险的方法。

但我觉得,我仍然无法做到100%无风险。

万一我买的滤芯质量很差怎么办?万一

我的过滤方法有问题怎么办?

万一我的Bac水本身就有点问题怎么办?(我从不检测我的Hospira水)

万一我的滤芯、过滤方法和Bac水本身都没问题,但它们却无法过滤/控制样品瓶中的特定霉菌/酵母/细菌怎么办?

这就是为什么每个人都需要认真考虑自身风险的原因。
 
我的理解没错吧,它不会变浑浊?如果不用测试就能检测出来就好了。而且,如果溶液变浑浊,那很可能是细菌pH值的问题,而不是肽的问题,所以很可能可以放心使用,这一点似乎存在争议。
 
Loosehead said:
Am I right in saying that it isn’t going to go cloudy? Sure would be nice if it could be detected without test. And is it fair to say then, because there seems to be some debate, if it’s cloudy it is most certainly a Bac ph issue not the peptide and likely fine to use?

Unfortunately no. According to ppl who know more than I do, the cloudiness can mean the pep is not binding with excipients. If that’s the case, the peps are not bioavailable to us (ie., useless). Also, the cloudiness could be caused by a defect that occurred during the lyophilization process, which means the Bac ph might be irrelevant to the cloudiness problem.
 
Retazempic said:
Unfortunately no. According to ppl who know more than I do, the cloudiness can mean the pep is not binding with excipients. If that’s the case, the peps are not bioavailable to us (ie., useless). Also, the cloudiness could be caused by a defect that occurred during the lyophilization process, which means the Bac ph might be irrelevant to the cloudiness problem.
Ah……once again…well, shit.
 
BNLFL said:
My side effects are some heartburn on pin days. I and my wife are both on 6mg. Not sure how much difference this has made, but we've stuck with Lilly's test schedule. Started 2mg for 4 weeks, then bumped up 2mg every 4 weeks. Everyone is different. YMMV
I wish I had ANY side affects to know that ive actually gotten Reta. Only side affect was no appetite for 2 days at 0.5mg. After that and titrating up too quickly, I have no side affects (week 5 and today, 6, I pinned 5mg). I am a big dude thoigh so not sure if that plays a role (6ft 290lbs). But I dont even have appetite suppression at this dose. Makes me thing I got either flaked by them or something idk. Its a vendor from this forum too that posts a lot. Not gonna say the name, because rules, but I might have to switch to someone else. And yes I use a calculator online to double check my reconstitution n all to get the accurate dosage.
 
Tator said:
I wish I had ANY side affects to know that ive actually gotten Reta. Only side affect was no appetite for 2 days at 0.5mg. After that and titrating up too quickly, I have no side affects (week 5 and today, 6, I pinned 5mg). I am a big dude thoigh so not sure if that plays a role (6ft 290lbs). But I dont even have appetite suppression at this dose. Makes me thing I got either flaked by them or something idk. Its a vendor from this forum too that posts a lot. Not gonna say the name, because rules, but I might have to switch to someone else. And yes I use a calculator online to double check my reconstitution n all to get the accurate dosage.

I hear many ppl don’t get a result until 6mg, and others don’t see a result until 8 or 9mg. So you still have runway to titrate up.

Did you ever take another GLP1 that you can compare with?

Is your Reta cloudy or clear after reconstitution? If cloudy, it might be ineffective.

You should consider joining a test group
 
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