Is 4mg+ really the key?

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BNLFL said:
Wait till you hit 8mg. Wife and I kind of slowed down/stalled on the last 2 6mg and two weeks at 7mg. Started 8mg and zing, appetite suppression is back, weights down 3.2lbs on my Tuesday check. BMI was down .5 and BF down .6% in 4 days
I need all the zing I can get !! 😉
 
Reta melted the fat off my body at 1mg twice a week. It went after the fatty parts I would have preferred to keep first. Then it started on my stomach and arms.

I was getting full benefits and some side effects at that dose and when I tried to move up to 1.5 on the misguided idea that I’d see “full benefits” at higher doses I got good and sick instead.

We are all designed differently. Listen to your body.
 
I didn’t see any loss at 12mg and even then had to add a couple mg of tirz to round it out. That broke a 6 month or so stall. However long it took to titrate Reta to 12
 
I am seeing slow fat loss with low dose, .75mg twice a week. I am moving to 1mg twice a week. But I also take Tesa/Ipa blend and Mots-c…
 
I was wondering the same thing. Both my wife and I are on around 1mg weekly with the aim to turn some fat into muscles rather than purely lose weight. I am still playing to find the sweet spot, likely we will stay around 0.8 - 1.2 for now. With these dosages we did see, particularly in my wife, an increase in heart rate, which according to my research on the internet is an indicator of glocagon response.

The 4mg (and I would prefer not to go that far myself) come from the fact that during the Eli Lilly trials BHB - the ketone the body makes through fat oxidation - became clearly measurable in the participants blood samples, well later than measurable acivation of GLP1 and GIP (EC50 for glucagon activation is nearly 10x that of the other receptors, meaning it is a lot slower to achieve its full (or half in that case) effect. )

One more thing: There is a likely a big difference from person to person. From a ketogenic (ultra low carb) diet that keeps you in a fatburnign state I know that some people are very quick to go into a keto state (= produce BHB) and others, particularly those which are heavily overweight and were used to eating throughout the day) take a lot longer since the body "forgot" how to make ketones. Going into Keto, sometimes adding a BHB salt can help in that situation since having BHB in the blood can support the body to acticate the creation of BHB by the liver. If that is in ANY way at all appliccable for Reta I have no idea, but what I take from that is that bodies react very differntly to a number of factors.
 
I should have added, I am not trying to loose a lot of weight. Maybe 10 pounds total. I already have abs, not too much sub fat but I have visceral fat. I have lost a lot in 3 months with those stack, just looking to loose as much as possible for health reasons.

So the reta dosage really depends on what you are trying to achieve…
 
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