Injection sites

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I've started pinning more on my hips and butt. Still some on the abdomen, but ones that leave more reactions like MOTS-C and NAD+ are all on hip or butt. Been thinking to do some IM, I do my TRT IM and Glutathione IM and they seem to have no injection site reaction. Gluta does burn a bit, but no swelling. I heard a podcaster the other day say he does most peps IM now. Anyone else try this? My preferred IM site is thigh, feel no pain, even with a 25g 1inch needle. First week of TRT had some soreness, but that is gone now too.
 
6friedeggs said:
Do you notice any stronger reactions depending on injection site?

For what it's worth, in Lilly's studies of Tirzepatide, it showed higher absorption level/concentration in bloodstream when it is injected in the abdomen compared with thigh or arm. I don't know if that holds true for other peptides, but maybe.

ClinicalTrials.gov

clinicaltrials.gov

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To be clear, the body absorbs the same amount. The abdominal injections are just absorbed faster:

Gemini said:
Thigh injections significantly reduce gastrointestinal side effects (like nausea and vomiting) at the cost of less pronounced immediate appetite suppression, whereas abdominal injections maximize appetite suppression but carry a substantially higher likelihood of gastrointestinal discomfort.

For instance, nausea was reported by only 20.8% of participants who used the thigh, compared to 37% who used the abdomen. Vomiting rates were also lowest in the thigh ( 7.6% vs. 16.7% in the abdomen).

The upper arm generally occupied a middle ground for both appetite suppression and gastrointestinal side effects.
 
I want to second the love for Easy Touch syringes. Much, much, much better and not that much more expensive than Amazon no name boxes.
 
My skin/body is such a little bitch. Pinning Reta and cag weekly in my stomach is fine, no issues. But any other peptide gives me insane ISR (picture from pinning glut 2 days ago in two seperate sites). I find pinning my thighs where there’s less fat weirdly hurts less for the others and my ISR is tiny (second pic are my glow pins)
 
I only take glutathione by IM now. Last time I did subq, it looked like road rash, despite being well diluted.

JourneyToPerfection said:
I find pinning my thighs where there’s less fat weirdly hurts less for the others and my ISR is tiny
For subq, another area that may hurt less is the side hip area, under the love handles.
 
Lower abdomen fat for everything except mots-c, which gives me an itchy lump so I do that in my thigh where I have a malfunctioning nerve so it is less itchy.
 
IM glutes : >1mL of whatever stings. Usually L-carnitine, vitamins, etc

IM delt : <=1mL of oils or peps inc I want absorbed quickly, including HGH and NAD+

SQ abdomen : strictly reserved for KLOW
 
Calm Logic said:
I only take glutathione by IM now. Last time I did subq, it looked like road rash, despite being well diluted.

For subq, another area that may hurt less is the side hip area, under the love handles.
Yeah mine came ready to inject with vit c and zinc so I should’ve known how bad it’d sting & react.

I’m such a sook at the thought of IM injecting though, might wait until I order a kit of just Glut instead of the mixed stuff I have. Do you get any pain using glut via IM?
 
Great post and perfect timing. I was going to ask about pinning TB-500 or BPC-157, whether they needed to be pinned near the injury intended to be treated. Been pinning near shoulder with cuff tear.

Under the arm pits? I haven't tried that area yet. Thanks!
 
I started with abdominal injections for about a year, then rotated to the hips/flanks for another six months. Over time, as body fat decreased in those areas, injections became more sensitive and less comfortable.

So far, upper outer glute/buttock subcutaneous injections have worked best for me. I alternate sides and stay in the fatty tissue.

In general, most peptides that are intended for subcutaneous use can be injected into the abdomen, upper thigh, hips/flanks, or upper outer glute area. Rotation matters more than the specific peptide for most people, since repeatedly using the same spot can lead to irritation, tenderness, or scar tissue.

One thing to be careful about with glute injections is avoiding the central/inner areas where larger nerves run deeper .... especially the sciatic nerve. With a shallow subq insulin pin and proper placement in fatty tissue, the risk is low, but hitting an irritated area can definitely be painful and is something you notice immediately.

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BNLFL said:
Shots in the butt hurts? I was going to to that area this morning. What syringes are

IM glutes : >1mL of whatever stings. Usually L-carnitine, vitamins, etc

IM delt : Click to expand...
 
homebrew said:
Great post and perfect timing. I was going to ask about pinning TB-500 or BPC-157, whether they needed to be pinned near the injury intended to be treated. Been pinning near shoulder with cuff tear.

Under the arm pits? I haven't tried that area yet. Thanks!
Yeah, I had constant tendon issues in my forearms near the elbow that would flair up weekly after heavy training sessions. I found that pinning (KLOW in my case) closer to the sight definitely sped up recovery over weeks where I pinned the abdomen.

How is it working out for you so far?
 
sloan980 said:
Yeah, I had constant tendon issues in my forearms near the elbow that would flair up weekly after heavy training sessions. I found that pinning (KLOW in my case) closer to the sight definitely sped up recovery over weeks where I pinned the abdomen.

How is it working out for you so far?
My shoulder cuff tear seems much better. One more week before taking 4 weeks off TB-500.
 
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