I learned that you shouldn't do this with retatrutide.

[Omxxl]

I wish I had found this when I started. Things I learned the hard way and that you shouldn't do with Retatrutide:

1- Not drinking enough fluids and not including mineral salts and electrolytes. You dehydrate very quickly with Retatrutide.

2- Cutting calories by more than 1000 kcal was crazy, and I lost almost as much muscle as fat. Remember that Retatrutide increases your basal metabolic rate.

3- Not getting enough protein (I always did this correctly, but many people make mistakes). Aim for 2 grams per kilogram of body weight of muscle mass.

4- Starting with very high doses or increasing them too quickly. I was cautious and started with 0.5 mg and then spent 4 weeks on 1 mg.

5- Thinking it's Tirze or Sema; it's not the same at all. Appetite suppression is less pronounced, and Retatrutide works in the long term.

6- Not weight training; this is a very common mistake. I love it, but a lot of people make mistakes here. I think that training, along with protein, is vital for maintaining muscle mass.

7- Thinking that Reta is some kind of magic bullet and that it alone solves everything is wrong. It's not just one tool in a protocol. Monitor your workouts and your diet, and don't skip meals.

What would you add? I'm reading your comments, friends!

 

[tendency]

8 - for some, important to keep the carbs up as well.

 

[yrrdead]

Pretty good list, my only nitpick is with #3.

Completely overblown both for weight loss/glp1s and just in general. For 99.99% not necessary. Also carbs are fine.

 

[Omxxl]

8 - for some, important to keep the carbs up as well.

100% agree! I noticed a big improvement by including more carbs in my diet while maintaining the same deficit.

 

[tendency]

100% agree! I noticed a big improvement by including more carbs in my diet while maintaining the same deficit.

Same here - reta and low carb did not mix well for me.

 

[BNLFL]

I'll vouch for #1. My sodium and chloride came back a little low in recent blood work. I just added sodium by drinking a gatorade/zero daily. I have liquid IV here, but 500mg each. I did two of those one day a little while back and my BP went to 140/89. It's normally 125/72. I normally check it once a week along with HR and O2.

 

[hoochiscrazy]

Is it possible to prevent muscle loss while on reta or is that just part of the bargain with weight loss?

 

[yrrdead]

Is it possible to prevent muscle loss while on reta or is that just part of the bargain with weight loss?

With any serious weight loss there is going to be muscle loss. TANSTAAFL**. You can reduce it with both training and diet. This is going to vary quite a bit from person to person based on all those factors including individual genetics.

**There are ways to avoid muscle loss and even gain muscle during a deficit but that is going to require AAS and all that entails.

 

[Jaylar]

Hey appreciate the post very good information as me and my wife are just waiting are delivery of reta and these tips will be beneficial.

 

[Mr. Blonde]

Is it possible to prevent muscle loss while on reta or is that just part of the bargain with weight loss?

Any time you are in a caloric deficit and losing weight, some will always be muscle. However, eat plenty of protein and strength train. Doing this will minimize the amount of muscle loss.

 

[Omxxl]

Is it possible to prevent muscle loss while on reta or is that just part of the bargain with weight loss?

It's possible with anabolic steroids or HGH, but that's entering a different realm, and we need to consider the side effects. I'm currently on TRT, and it minimizes muscle loss.

 

[chipsandsalsayall]

I appreciate the info in this post. At some point I may make the jump from Tirz to Reta (but Tirz is still doing what it's supposed to do). I'm feeling like this info is applicable to Tirz usage as well. I've been "carb-avoidant" but it sounds like I can relax on that a bit.

 

[Rezwalker]

I learned the hard way too.

I titrated a bit too fast—1 mg for 2 weeks, then 2 mg for 2 weeks. The second week at 2 mg was the tipping point.

I had a lot of GI issues, or it might have been food poisoning from some bad chicken. Either way, it’s been hard to get food in.

I’ll skip my dose today and restart at 1 mg once I can get back to 2,000 calories per day. Losing muscle is out of the question I’ve worked too hard!

 

[Galapagosfit]

alocohol when taking reta, i tried 2 times drinking alcohol . It made my sleep horrible, i was nauseous for almost 3hours. and it was really not that much, 2 drinks the first time, and the second time was like 2-3 beers. I really think i'm done drinking. not worth it.

 

[RosebudFox]

Pretty good list, my only nitpick is with #3.

Completely overblown both for weight loss/glp1s and just in general. For 99.99% not necessary. Also carbs are fine.

Resistance training is the key to building and maintaining muscle. My overall body composition did improve when I started to eat more protein, but I think I was just eating cleaner in general.

 

[Such1943]

People need to remember to simply get up and move. Go out, walk, and enjoy the process of losing weight. Staying sedentary is what got many of us here in the first place, so that habit has to change.

 

[sfkid]

Pretty good list, my only nitpick is with #3.

Completely overblown both for weight loss/glp1s and just in general. For 99.99% not necessary. Also carbs are fine.

If you want to lose FAT, this is ABSOLUTELY the MOST important factor. If you want to lose weight (muscle and fat) then you are correct.

For those that want to do a recomposition ( lose fat, gain or keep muscle) you need to eat a high protein diet or else you will lose muscle. There is no way around this - this is just how a calorie deficit works.

 

[sheilarae74]

All of these things mentioned are 100% my experience. I eat more now, especially carbs, than I have in the past year and I STILL lose 1-2lbs a week. You definitely don't have to starve yourself on reta or titrate up to full dosage quickly or if ever to make it work. You just have to work those muscles and ingest some protein.

 

[deleted.user.16]

All of these things mentioned are 100% my experience. I eat more now, especially carbs, than I have in the past year and I STILL lose 1-2lbs a week. You definitely don't have to starve yourself on reta or titrate up to full dosage quickly or if ever to make it work. You just have to work those muscles and ingest some protein.

Just saying, this is not true for everyone. I absolutely cannot eat more and lose weight (especially carbs). I only lose if I eat way less.

 

[Omxxl]

I see that most people have gone through the same thing, and that is because retatrutide is very different from other GLP-1 inhibitors and completely changed with the glucagon pathway.