我的医生将我服用的药物从7.5毫克的泽泊汀（Zepbound）换成了10毫克的复方替拉唑肽（Tirzepatide，购于Hallandale药房）。尽管复方药物的剂量更大，但说实话，它对我没有任何帮助。我没有任何常见的副作用，也没有食欲抑制。您能想到任何原因吗？您认为如果她将我的剂量增加到最大剂量15毫克，会有帮助吗？
化合物 Tirezepatide 的效力是否比市售 ZepBound 弱？
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可能是他们的原材料剂量不足，他们没有进行检测，所以不知道。
不幸的是，自制药物的填充量常常会与预期存在一定偏差。我们这些DIY爱好者如此注重测试的原因之一，就是为了精确掌握填充量，以便准确计算剂量。
就我个人而言，如果可以的话，我会先观察一段时间，或者尝试在规定剂量的基础上额外服用约10%，看看是否有效果。
就我个人而言，如果可以的话，我会先观察一段时间，或者尝试在规定剂量的基础上额外服用约10%，看看是否有效果。
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I'm all in on making informed choices about peptides.
My attempt at being helpful is a Quality vs Price comparison spreadsheet of US Peptide vendors.
I began compiling it when I saw the end of insured Wegovy rapidly approaching.
There is a bit of a preamble then a link to a Google Drive permalink.
Feel free to make suggestions for improvement, it's a work in progress:
-----
" When I lost my group insurance I searched for low-cost Wegovy replacements. I found huge price differences between vendors, and, QA practices that varied widely.
To be helpful I compiled my results on 20+ US GLP-1 vendors who will sell single vials. Prices are shown for research Semaglutide, Tirzepatide and Retrutatide. Color coding and QA Notes have relevant Quality Info.
The PREFERRED, MOST TRANSPARENT Quality Assurance for peptide users is a Batch Certificate of Anaysis (COA) prepared by an Independent 3rd Party laboratory that is Current, Credible AND LINKED TO EVERY VIAL (LTEV) SOLD. The linking may be by batch number on the vial label, printed QR code hyperlinked to an online COA, or by a naming convention which uniquely identifies the product as part of a unique COA'd batch. Some *** vendors do all three things.
A COA shows the IDENTITY, PURITY and QUANTITY of peptide present in the sample vial. PURITY of product must be Pharmaceutical Grade per the United States Pharmacoepeia (USP) i.e. above 99% pure. QUANTITY MUST BE SPECIFIED AS IT IS ESSENTIAL to obtaining the correct dosage when you reconstitute lypophilized peptides. Some vendors omit QUANTITY as it would reveal their under-dosed, weak and therefore more profitable product offerings - you should not purchase from these vendors.
*** VENDORS with COAs LTEV are considered Highest Quality, marked with a triple asterisk (***) and are sorted to first on this spreadsheet. Strongly consider these vendors if buying the most highly Quality Assured GLP-1 product is your goal.
GREEN = GOOD - HAS PRESENT Current Credible 3RD Party Certificate Of Analysis (COA) showing Identity, Purity and Quantity of peptide. Not necessarily LTEV but observable onsite.
YELLOW = CAUTION - LACKS Current Credible 3RD Party COA OR Has Unsatisfactory Processes OR there is notable, credible negative reporting by users. This last is my own observation and is subjective.
YELLOW/GREEN = MIXED RESULTS Check QA notes for further information before making a purchase.
FULL DISCLOSURE: Information was obtained by organic Google Searches and my own non-medical-professional observations. It is believed accurate at posted DATE on spreadsheet but not guaranteed. My wife's Semaglutide comes from Aminos Research while my own Semaglutide, Tirzepatide and Retatrutide has come partially from Aminos Research and also from other less well QA'd sources. I do not accept any form of compensation from any source, and, I prefer not to 'recommend' individual vendors. "
GLP-1 Price vs Quality US.pdf
drive.google.com
My attempt at being helpful is a Quality vs Price comparison spreadsheet of US Peptide vendors.
I began compiling it when I saw the end of insured Wegovy rapidly approaching.
There is a bit of a preamble then a link to a Google Drive permalink.
Feel free to make suggestions for improvement, it's a work in progress:
-----
" When I lost my group insurance I searched for low-cost Wegovy replacements. I found huge price differences between vendors, and, QA practices that varied widely.
To be helpful I compiled my results on 20+ US GLP-1 vendors who will sell single vials. Prices are shown for research Semaglutide, Tirzepatide and Retrutatide. Color coding and QA Notes have relevant Quality Info.
The PREFERRED, MOST TRANSPARENT Quality Assurance for peptide users is a Batch Certificate of Anaysis (COA) prepared by an Independent 3rd Party laboratory that is Current, Credible AND LINKED TO EVERY VIAL (LTEV) SOLD. The linking may be by batch number on the vial label, printed QR code hyperlinked to an online COA, or by a naming convention which uniquely identifies the product as part of a unique COA'd batch. Some *** vendors do all three things.
A COA shows the IDENTITY, PURITY and QUANTITY of peptide present in the sample vial. PURITY of product must be Pharmaceutical Grade per the United States Pharmacoepeia (USP) i.e. above 99% pure. QUANTITY MUST BE SPECIFIED AS IT IS ESSENTIAL to obtaining the correct dosage when you reconstitute lypophilized peptides. Some vendors omit QUANTITY as it would reveal their under-dosed, weak and therefore more profitable product offerings - you should not purchase from these vendors.
*** VENDORS with COAs LTEV are considered Highest Quality, marked with a triple asterisk (***) and are sorted to first on this spreadsheet. Strongly consider these vendors if buying the most highly Quality Assured GLP-1 product is your goal.
GREEN = GOOD - HAS PRESENT Current Credible 3RD Party Certificate Of Analysis (COA) showing Identity, Purity and Quantity of peptide. Not necessarily LTEV but observable onsite.
YELLOW = CAUTION - LACKS Current Credible 3RD Party COA OR Has Unsatisfactory Processes OR there is notable, credible negative reporting by users. This last is my own observation and is subjective.
YELLOW/GREEN = MIXED RESULTS Check QA notes for further information before making a purchase.
FULL DISCLOSURE: Information was obtained by organic Google Searches and my own non-medical-professional observations. It is believed accurate at posted DATE on spreadsheet but not guaranteed. My wife's Semaglutide comes from Aminos Research while my own Semaglutide, Tirzepatide and Retatrutide has come partially from Aminos Research and also from other less well QA'd sources. I do not accept any form of compensation from any source, and, I prefer not to 'recommend' individual vendors. "
GLP-1 Price vs Quality US.pdf
drive.google.com
Fyi, all the sudden the side effects of compound TIRZ hit me. But, it didn't start until 48 hours after my injection (whereas the ZepBound hits me 12 hours later).
I would look up news articles on that pharmacy that were just released.Approach said:
I am on compounded. And mine was rerouted to another pharmacy because of some issues going on.
There are no recent news articles, and the "issue" is that one of the major telehealth companies bought their own compounding pharmacy and are being dishonest about why they are moving customers to that new pharmacy so it doesn't appear like the big money grab that it is.Gwenhwyfar227 said:
Oh really? I was unaware. Someone the groups I belong to shared some snippets. Sorry for the misinformation. I certainly didn't mean to spread any.
Well that telehealth is definitely being dishonest in their communication to their clients as I received "recent regulatory actions taken against Pharmcore dba" as the reason it was being redirected.
Well that telehealth is definitely being dishonest in their communication to their clients as I received "recent regulatory actions taken against Pharmcore dba" as the reason it was being redirected.
Yeah, there was some buzz about it on Reddit over the past several days, but on digging it turns out that the "regulatory action" was from 2022 when Hallandale was in the middle of moving to a new facility. Of course Mochi forgets to tell you that they started the transition to Aequita months ago and only continued using Hallandale for states where Aequita wasn't yet licensed. Once the licenses were in place they decided to stop paying Hallandale for orders that customers had already paid for and came up with this neat lie to cover their tracks...Gwenhwyfar227 said:
Here's a couple interesting links and some pix:
We're Partnering With Aequita Pharmacy: Here's What To Expect
We're joining forces with Aequita Pharmacy to launch a medication program, making safe and effective medications more widely accessible to Mochi Health patients.
www.blogs.joinmochi.com
Mochi Health
<p>At Mochi Health, we excel at conquering challenges and creating inventive solutions for the betterment of people's well-being. Our culture embraces inclusivity and diversity, empowering both our patients and team members through the sharing of knowledge and information. Although we may not...
boards.greenhouse.io
This is how Mochi/Aequita ship their meds, using freeze pops to aid in cooling:
And this is how Hallandale ships their meds:
Attachments
I was aware of the move to Aequita. And had my suspicions that they owned it.
How nasty to treat Hallandale that way when they handled the majority of the orders for them..
How nasty to treat Hallandale that way when they handled the majority of the orders for them..
That is really crappy behavior on the part of Mochi. If there were regulatory actions against Hallandale, I believe Mochi would have said what regulatory actions and by whom.ZippityDooDah said:
The owner posted a very long message last night explaining their break with Hallandale. I just know I want to get away from that whole area and just worry about doing my own thing.lol
From nearly 6 years ago.Batscout said:
I'm no fan of most compounding pharmacies, but in this instance the whole Mochi/Aequita thing is just proof of how sleazy the owners are.
See corresponding Close Out letter stating that all issues have been addressed.Batscout said:
Pharmcore Inc. dba Hallandale Pharmacy - 605569 - 05/03/2022
Compounding Pharmacy/Adulterated Drug Products
www.fda.gov
For me, it felt underdosed the one month I used compound.Approach said:
YOU are. My favorite Redditor, SIR!dionysos said:
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