I'm 46F, 5'4" HW 210 SW 189 CW 175. I know a lot of people dread the BMI calculation, but it works for me, petite sedentary female. I have my goals set into stages, my first goal is to get out of the obesity range and into overweight, so that's 170 lb.
Next is to get into the normal range, with 25 BMI, so that's 150 lb.
After that, my next target is "middle of the way" ~22.5ish BMI with 132 lb.
My final target, and that's where I want to stop for maintenance is the lower end of normal BMI ~20, which puts me between 112-120 lb. I was my healthiest when I was there, and it gives me wiggle room to adapt.
It's an aggressive final goal, and there's a chance that I can't really reach it at my age, with a bunch of metabolic issues and being in perimenopause. Honestly ANY progress towards a healthy weight is a win. And I understood early on that I'll need GLP-1s for life.