HGH and RT: the best combination?

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Omxxl

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I'm about to buy HGH because of the low price I found for 24 IU.

I'm currently taking Reta 2mg weekly. After reading many studies on GLP-1 and HGH and their synergies and benefits when taken together, like this article:

https://ampouletude.com/article/combined-rhgh-glp1-agonist-body-recomposition-fat-loss-muscle-gain-metabolic-health

I think it could be very good for body recomposition.

What do you think? Has anyone tried it?

I'll be using this therapy for the next 6 months and I'll let you know the results.
 
Omxxl said:
I'm about to buy HGH because of the low price I found for 24 IU.

I'm currently taking Reta 2mg weekly. After reading many studies on GLP-1 and HGH and their synergies and benefits when taken together, like this article:

https://ampouletude.com/article/combined-rhgh-glp1-agonist-body-recomposition-fat-loss-muscle-gain-metabolic-health

I think it could be very good for body recomposition.

What do you think? Has anyone tried it?

I'll be using this therapy for the next 6 months and I'll let you know the results.
Id be very interested in this too. Oddly enough im about to start the same.

Have been on Reta for almost 6 months now and plan on starting 2iu before bed every day - starting next week.

Perhaps we can compare notes as we go?

Side Note: Im not on any PEDs or TRT etc. No 'enhancements' so to speak.
 
Bunts said:
Id be very interested in this too. Oddly enough im about to start the same.

Have been on Reta for almost 6 months now and plan on starting 2iu before bed every day - starting next week.

Perhaps we can compare notes as we go?

Side Note: Im not on any PEDs or TRT etc. No 'enhancements' so to speak.
FWIW,

I've been using gh alongside Tirz/Reta for about a month now. I stick to 1.5-2iu per day as my blood sugar runs the best in that range, slightly lower than pre hgh. Before gh I ran Tesa/Ipa for a short spell. Both hgh and Tesa/Ipa had a similar effect on shrinking my stomach quicker, but the hgh effects overall seem more pronounced and it's cheaper by a fair margin. This is by no means advice, just my experience in the short time that I've used them.

Chopper
 
Chopper said:
FWIW,

I've been using gh alongside Tirz/Reta for about a month now. I stick to 1.5-2iu per day as my blood sugar runs the best in that range, slightly lower than pre hgh. Before gh I ran Tesa/Ipa for a short spell. Both hgh and Tesa/Ipa had a similar effect on shrinking my stomach quicker, but the hgh effects overall seem more pronounced and it's cheaper by a fair margin. This is by no means advice, just my experience in the short time that I've used them.

Chopper
Same here
 
I'm not discouraging you from trying rHGH, whether you got it for a deal or not. Many use it and have great things to say. I am curious myself.

For improved body comp, I suggest going up from 2 mg Reta first. Then try a GH secretagogue like Tesamorelin first before HGH. You can get a significant increase in IGF-1 from Tesamorelin, without shutting down your endogenous GH production. Tesa is not an overnight cure - it's a slow but proven thing for belly fat and recovery.

After a couple of months at 6-8 mg Reta + 1-2 mg Tesa, you still want more, then: TRT, HGH, Ostarine await.
 
I’m now on Test, Reta, and HGH. Been on test for years. Just started Reta again 5 weeks ago. And started HGH about the same time.

Haven’t noticed any changes in my physique so far. Am down a few lbs but I’ve also been more disciplined with macros/calories. Biggest thing I’ve noticed was HGH has vastly improved my sleep. Which I’m sure is improving other things.
 
Dogmandu said:
I'm not discouraging you from trying rHGH, whether you got it for a deal or not. Many use it and have great things to say. I am curious myself.

For improved body comp, I suggest going up from 2 mg Reta first. Then try a GH secretagogue like Tesamorelin first before HGH. You can get a significant increase in IGF-1 from Tesamorelin, without shutting down your endogenous GH production. Tesa is not an overnight cure - it's a slow but proven thing for belly fat and recovery.

After a couple of months at 6-8 mg Reta + 1-2 mg Tesa, you still want more, then: TRT, HGH, Ostarine await.
I've been on TRT since 2022. I've tried HGH three times in my life, but never with Reta, and I loved its potential. The magic of HGH is that its effects appear after several months.

The problem I had was with my blood sugar; when I used it for six months, it caused insulin resistance.

Reta improves that aspect, and I see it as a winning combination.

I'll buy enough for a year and start my next protocol:

Month 1: 2 IU HGH 2.5 mg RT

Month 2: 3 IU HGH 3 mg RT

Month 3: 3 IU HGH 3.5 mg RT

Month 4: 4 IU HGH 4 mg RT

Month 5: 4 IU HGH 3 mg RT

Month 6: 4 IU HGH 2 mg RT

What do you think? This is in addition to my TRT of 125 mg/week of testosterone enanthate.
 
Dogmandu said:
I'm not discouraging you from trying rHGH, whether you got it for a deal or not. Many use it and have great things to say. I am curious myself.

For improved body comp, I suggest going up from 2 mg Reta first. Then try a GH secretagogue like Tesamorelin first before HGH. You can get a significant increase in IGF-1 from Tesamorelin, without shutting down your endogenous GH production. Tesa is not an overnight cure - it's a slow but proven thing for belly fat and recovery.

After a couple of months at 6-8 mg Reta + 1-2 mg Tesa, you still want more, then: TRT, HGH, Ostarine await.
From my research (just a guy on the internet) while it does "shut down endogenous production", it returns after stopping exogenous hgh rather quickly. But correct me if I've misspoken
 
Volkswagen57 said:
From my research (just a guy on the internet) while it does "shut down endogenous production", it returns after stopping exogenous hgh rather quickly. But correct me if I've misspoken
I’ve also read that. Endogenous production returns within days. Not sure about super doses though.
 
Many studies demonstrate normalization after a period of time using rHGH.

Studies indicate that endogenous HGH secretion begins to recover shortly after discontinuing the injection. In some treatment studies, endogenous levels began to show signs of recovery 24–36 hours later and returned to control levels within 48–60 hours.

Even after prolonged use (e.g., two years), the pituitary gland appears to be able to resume natural HGH production.
 
I assume you are planning on checking IGF-1 levels ( and blood pressure, lipids and glucose ) before you start and after. I do not know your age, but those doses are significantly higher than physiological at all ages and could cause long term health risks, mainly cardiovascular ones. Making sure IGF-1 is not super high might at least reduce those risks. My IGF-1 went to 50nmol/l or 5 standard deviations above normal on 1.5iu/day, which is definitely not safe. ( taking it to try to help maintain a 54% weight loss )

The article mentioned at the top, is not pseudoscience, which is good, but a balanced presentation of the information would have a lot more uncertainty, and much more discussion of the risks of hgh therapy. There is no established scientific research on the combination in humans, it is all theoretical. Doctors do not use hgh for weight control or muscle maintenance /improvement as the risks are thought to outweigh the benefits. Reading about hgh and its side effects is essential before starting it , preferably from scientific papers or solid science based sources. Anyone selling anything can be a source of biased or incomplete information.
 
You might put in "for my age" with your 5 standard standard deviations. My igf1 is 2.3 standard deviations elevated for my age but inside range for a younger man. Which has been my aim in TRT. Perhaps it's not unsafe but "definitely not safe" is a bit alarmist I imagine.
 
Omxxl said:
I've been on TRT since 2022. I've tried HGH three times in my life, but never with Reta, and I loved its potential. The magic of HGH is that its effects appear after several months.

The problem I had was with my blood sugar; when I used it for six months, it caused insulin resistance.

Reta improves that aspect, and I see it as a winning combination.

I'll buy enough for a year and start my next protocol:

Month 1: 2 IU HGH 2.5 mg RT

Month 2: 3 IU HGH 3 mg RT

Month 3: 3 IU HGH 3.5 mg RT

Month 4: 4 IU HGH 4 mg RT

Month 5: 4 IU HGH 3 mg RT

Month 6: 4 IU HGH 2 mg RT

What do you think? This is in addition to my TRT of 125 mg/week of testosterone enanthate.
Based on your original post, I'll assume body recomp is the key goal for you.

Your 125 mg test per week will help. Training hard is (obviously) a non-negotiable, so nothing more to add on that.

To be blunt, your plan seems low reward + high risk to me. The best plans are the opposite. Since you developed insulin resistance with HGH (this is a real problem), then I do not understand why you have Reta peaking at just 4 mg. Why lean on 4 IU of HGH with its known list of risks? Yet you are not leaning heavier into Reta, which is far less risky and will do both - body recomp and manage blood glucose?

By Month 6, if it were me, I'd be at <3 IU HGH + 8-10 mg Reta. Better yet, I'd be at 1 mg daily Tesamorelin + 8 g Reta if tolerated, which is a low-risk + high-reward plan.

Also, get an IGF-1 reading at 2, 3, and 4 IU and let that drive your dosing. HGH can easily drive IGF-1 to supraphysiological levels, bypassing feedback loops...unless you are measuring and adjusting. I doubt you'd need to be worried about 2 IU, but I wouldn't fly blind with 4 IU. At 4 IU and higher, insulin resistance is not your biggest risk!
 
Dogmandu said:
I'm not discouraging you from trying rHGH, whether you got it for a deal or not. Many use it and have great things to say. I am curious myself.

For improved body comp, I suggest going up from 2 mg Reta first. Then try a GH secretagogue like Tesamorelin first before HGH. You can get a significant increase in IGF-1 from Tesamorelin, without shutting down your endogenous GH production. Tesa is not an overnight cure - it's a slow but proven thing for belly fat and recovery.

After a couple of months at 6-8 mg Reta + 1-2 mg Tesa, you still want more, then: TRT, HGH, Ostarine await.
I see where you’re coming from but I truly don’t think that a secretagogue would help, it’s just more time and money wasted, endogenous GH production bounces right back so you’re better off using the superior peptide. I do agree that he’s better off upping the Reta dose before getting on HGH though.
 
Dogmandu said:
Based on your original post, I'll assume body recomp is the key goal for you.

Your 125 mg test per week will help. Training hard is (obviously) a non-negotiable, so nothing more to add on that.

To be blunt, your plan seems low reward + high risk to me. The best plans are the opposite. Since you developed insulin resistance with HGH (this is a real problem), then I do not understand why you have Reta peaking at just 4 mg. Why lean on 4 IU of HGH with its known list of risks? Yet you are not leaning heavier into Reta, which is far less risky and will do both - body recomp and manage blood glucose?

By Month 6, if it were me, I'd be at
 
Omxxl said:
Thanks for the input. I wasn't thinking of increasing the Reta dose because I'm already experiencing quite a bit of nighttime nervousness with just 2 mg. But you're right about monitoring IGF1 and considering going above 2 IU of HGH.

On the other hand, I'll try a higher Reta dose as long as you can tolerate the side effects.
Fair enough. Side effects are a good reason to take it slow with Reta. I did. You may find that after staying at 4 mg Reta for a few months, giving your body time to adapt, that you can titrate up with less difficulty. It may be the initial few mg that cause problems. Also, see if a few days of moderate to high carbs help with sleep and night time nervousness.
 
Dogmandu said:
Fair enough. Side effects are a good reason to take it slow with Reta. I did. You may find that after staying at 4 mg Reta for a few months, giving your body time to adapt, that you can titrate up with less difficulty. It may be the initial few mg that cause problems. Also, see if a few days of moderate to high carbs help with sleep and night time nervousness.
Thanks for the advice! I learned it the hard way, since I had a rough time with the low-carb diet and the challenge. I increased my carbs and my sleep improved a lot, although it's still not like it was before the challenge.
 
Omxxl said:
Thanks for the advice! I learned it the hard way, since I had a rough time with the low-carb diet and the challenge. I increased my carbs and my sleep improved a lot, although it's still not like it was before the challenge.
Carbs!!

A lot of people bring their previous dietary habits/baggage over when starting Reta. Like low-carb or fasting. I know I did. I'd been low-carb for decade plus. Reta is already a soft fasting mimic. There's no need to strictly limit carbs on Reta. Reintroducing carbs, especially at dinner, improved sleep quality. I've rediscovered bananas, which I used to think of as sugar-filled franken-fruit. But I now eat one half-ripe banana before my workout and one after. Something that I would have never done pre-GLP. Half-ripe bananas are also rich in prebiotic fibers, which will fix Reta-associated constipation.
 
I've been running CJC(No DAC)/IPA for 2 months now with good results, however after doing some research am going to just move over to HGH 2-4IU at night.

My main concern is quality of HGH. I want to get a Chinese generic due to price (genuine generic, not unlabelled) but it's next to impossible to find any that ships to Australia.
 
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