服用了3倍剂量——真是倒霉透了

[drgnflydggr]

我从一月份开始服用瑞他曲肽。我非常缓慢地增加剂量，甚至因为3毫克的副作用太严重，把剂量从3毫克降到了2.5毫克。我读过其他人的帖子，说他们服用的剂量超过了预期，我一直坚信自己绝不会那样。朋友们，骄傲使人跌倒。今天我需要注射2.5毫克的剂量，但我忘记了需要重新配制药瓶。尽管感冒了，我还是硬着头皮配制了药瓶，然后注射了平时的2.5毫克剂量。一切顺利。然后我看了看我的瑞他曲肽套装，发现上面标着10毫克，心想：“糟了，我把10毫克的药瓶配好了，而不是我想要的30毫克的。没关系，我再算一下剂量，多注射一些就行了。” 聊天记录——我看到的是数量，把它和剂量搞混了。

所以，今天我只注射了7.5毫克的瑞他曲肽，而不是我计划的2.5毫克。还好，我储备了姜糖、电解质和止吐药。只是很害怕接下来的7-10天。之前我从2.5毫克增加到3毫克的时候，我停用了KLOW。我希望这种肽混合物能减轻一些剂量相关的胃肠道炎症，因为我已经重新开始服用它大约一周了。

祈祷好运。我会随着这周的进展更新帖子。祝我好运！

 

[deluge]

祝你好运！

我上周也犯了同样的错误，把单位和剂量搞混了。还好我的错误导致剂量过小。

现在我所有的注射笔上都贴了 P-touch 标签，上面写着产品名称、剂量和单位。

 

[drgnflydggr]

祝你好运！

我上周也犯了同样的错误，把单位和剂量搞混了。还好我的错误导致剂量过小。

现在我所有的注射笔上都贴了 P-touch 标签，上面写着产品名称、剂量和单位。

谢谢！说来你可能不信，我当时正准备拿出手机做个新标签，才注意到“剂量”不对。标签真的太重要了。对我来说，放慢节奏，在身体还没完全恢复的时候不要同时做很多事情，也是个很重要的教训。

感谢你的理解和支持。<3

 

[Chili777]

你可能一时半会儿排便不了，但你会没事的。你随身带着电解质饮料真是太好了。

 

[myboysherman]

Initially, I labeled vials by mg/ml, like 12:240 or 10:100. But I discovered that my lazy brain will just report, "tl;dr" and give me a guess. So from now on, I'll label them 1:10 or 1:20 or similar. I don't really care how many doses are inside, I run out when I run out.

That should read mg/U above. Otherwise, I'd be really far off. H/T @drgnflydggr

 

[drgnflydggr]

Initially, I labeled vials by mg/ml, like 12:240 or 10:100. But I discovered that my lazy brain will just report, "tl;dr" and give me a guess. So from now on, I'll label them 1:10 or 1:20 or similar. I don't really care how many doses are inside, I run out when I run out.

My typical labels are:

Med Name

Med Concentration (10 mg/ml)

Unit Conversion (10U = 1mg)

Date Reconstituted

Unfortunately a label wouldn’t have saved me this time - this was due almost entirely to carelessness/thoughtlessness and rushing while I had a cold. Over-confidence, maybe.

 

[bbbilly]

good luck solder. last time i took a little too much i threw my back out from the uncontrollable projectile vomiting. but that was from tirz, never dabbled with reta

 

[drgnflydggr]

Day Two: No appetite, some nausea but it’s well-controlled by Zofran.

I took the day off, so I’ve just been resting and watching “Designing Women” on Hulu. Miraculously, my cold symptoms are better today, too. My peak serum concentration will be in a few hours, but based on the ride up, I’m not expecting too much to be different. I’m already well above any previous peaks. Food-wise, I’ve been able to manage a few bites of Greek yogurt every couple of hours.

The trek continues. Thanks to everyone who commented for your suggestions and commiseration. Currently peaking according to the app I use.

 

[BNLFL]

I took the day off, so I’ve just been resting and watching “Designing Women” on Hulu.

Are you a female?

 

[bobbyjack]

Are you have any HR effects from the greater dose?

 

[RetCurious]

Day Two: No appetite, some nausea but it’s well-controlled by Zofran.

I took the day off, so I’ve just been resting and watching “Designing Women” on Hulu. Miraculously, my cold symptoms are better today, too. My peak serum concentration will be in a few hours, but based on the ride up, I’m not expecting too much to be different. I’m already well above any previous peaks. Food-wise, I’ve been able to manage a few bites of Greek yogurt every couple of hours.

The trek continues. Thanks to everyone who commented for your suggestions and commiseration. Currently peaking according to the app I use.

View attachment 19457

Looks like a rocket shot from here. It's been a couple of days since you checked in, hoping all's well.

 

[Cannonball72]

My typical labels are:

Med Name

Med Concentration (10 mg/ml)

Unit Conversion (10U = 1mg)

Date Reconstituted

Unfortunately a label wouldn’t have saved me this time - this was due almost entirely to carelessness/thoughtlessness and rushing while I had a cold. Over-confidence, maybe.

Literally just got my nimbot, this was the most intuitive way to label.

I also include dose frequency on the label.

 

[drgnflydggr]

Are you have any HR effects from the greater dose?

I’ve actually been paying closer attention to my resting heart rate and heart rate variability since I started taking reta in January. Before that, I had been eating terribly and drinking too much, and my HRV/RHR values showed that - all over the place. I cleaned up my diet, and I lost almost all desire to drink alcohol, so those two values snapped to a pretty tight baseline by early Feb.

Something interesting I’ve noticed with reta is that, when I take my weekly dose, my HRV declines and my RHR goes up and then they return to baseline before my next injection. My worst deviation from baseline was the time I increased from 2.5mg to 3mg while I was cycled off of KLOW. I was a wreck for two weeks, even though I stepped my dose back down to 2.5mg the following week. This time, with the 3x dose, I experienced my normal dip and recover - it’s only Saturday, three days in, and my HRV is already back above baseline. I’ll be interested to see if that stays consistent or if today’s an anomaly.

I did sleep terribly Thursday and Friday nights, and my watch alerted me to a higher than normal heart rate overnight. (50s instead of my normal 40s)

 

[drgnflydggr]

I’m on day 4. Still feeling pretty fatigued, still have some heartburn, but I’m sleeping better. Interestingly, the side effect I was most dreading, allodynia or “skin pain”, never materialized thank goodness.

Going forward, I plan to take next week off and start again on my 2.5mg dose on the following Wednesday. In case anyone finds this later on and are in a similar situation, the things that were most helpful to me were:

1. Electrolytes in water bottles, frequent small sips

2. Rest. Rest. Rest.

3. Don’t beat yourself up. Mistakes happen. Learn from it and move on.

4. Lay on your right side to encourage gastric emptying, left side to alleviate heartburn

5. This is an n=1 scenario, but I think the KLOW peptide blend was very helpful in reducing GI and inflammation, to the point that I won’t increase my dose if I’m not taking it.