Fat cell memory

[AlexSilver]

If it is white, it is not 5A1MQ. Per AI (which I hate even using), the color comes from the quinoline ring, which absorbs blue light, reflecting back orange. It does not come from iodide.

Stupid ai just told me it can only be white if it isn’t properly methylated.

 

[BlueDog55]

Not sure this is related but... I have for over 15 years been on a weight loss ride like most it's been a roller coaster. The one thing I have noticed and I have coined it my Fat clock... what I mean is the first time I lost from 405ish down to 360 and kept it like that for about a year then after some time I lost down to 335 what i noticed was if I fell back into my old ways I would gain back up to 360 very fast but then the weight gain would kinda level out/slow down for a while then if I got myself back on track I could get back down to 335 easier. Then after I kept myself at or around 335 for at least a year that became my new "clock" or set point. Same thing would happen I get down to 315ish and mess around and bam back to 335 very fast so on and on. I really believe there is something to this set point and that would be in the same ballpark as fat cell memory. My current clock is 305ish but with the help of Reta I am at 276 and going to try and make this my new setting as I work to get down to 250 and will hope to make that my set point. For reference I am 6'5" and 63yrs old now my 40's were my down fall years sure wish OI could redo them... But

 

[dondada109]

Not sure this is related but... I have for over 15 years been on a weight loss ride like most it's been a roller coaster. The one thing I have noticed and I have coined it my Fat clock... what I mean is the first time I lost from 405ish down to 360 and kept it like that for about a year then after some time I lost down to 335 what i noticed was if I fell back into my old ways I would gain back up to 360 very fast but then the weight gain would kinda level out/slow down for a while then if I got myself back on track I could get back down to 335 easier. Then after I kept myself at or around 335 for at least a year that became my new "clock" or set point. Same thing would happen I get down to 315ish and mess around and bam back to 335 very fast so on and on. I really believe there is something to this set point and that would be in the same ballpark as fat cell memory. My current clock is 305ish but with the help of Reta I am at 276 and going to try and make this my new setting as I work to get down to 250 and will hope to make that my set point. For reference I am 6'5" and 63yrs old now my 40's were my down fall years sure wish OI could redo them... But

Its real thats the thing. Just because I called it "fat cell memory" doesn't mean the concept is made up.

The term itself may not be scientific, but the underlying idea is supported by research. When people lose a significant amount of weight, fat cells mainly shrink rather than disapear. In adults, fat cell number tends to remain relatively stable, and previous obesity may leave long-lasting biological and even epigenetic changes that can influence future weight regain.

I'm not saying that regaining fat is inevitable, but it's not accurate to dismiss the concept entirely as a myth. There is evidence that adipose tissue retains certain characteristics after obesity, even after substantial weight loss.

As far as I know, there is currently no reliable way to significantly reduce fat cell number other than procedures such as liposuction. Weight loss primarily reduces the size of fat cells, not their number

Interesting paper to this subject, you guys can search it up.

Adipose tissue retains an epigenetic memory of obesity after weight loss" (Nature, 2024).

 

[BlueDog55]

Its real thats the thing. Just because I called it "fat cell memory" doesn't mean the concept is made up.

The term itself may not be scientific, but the underlying idea is supported by research. When people lose a significant amount of weight, fat cells mainly shrink rather than disapear. In adults, fat cell number tends to remain relatively stable, and previous obesity may leave long-lasting biological and even epigenetic changes that can influence future weight regain.

I'm not saying that regaining fat is inevitable, but it's not accurate to dismiss the concept entirely as a myth. There is evidence that adipose tissue retains certain characteristics after obesity, even after substantial weight loss.

As far as I know, there is currently no reliable way to significantly reduce fat cell number other than procedures such as liposuction. Weight loss primarily reduces the size of fat cells, not their number

Interesting paper to this subject, you guys can search it up.

Adipose tissue retains an epigenetic memory of obesity after weight loss" (Nature, 2024).

I feel like maybe after a year at a lower weight I lost some of the fat cells and that might be why I only shoot up to a point then level off. Does that make sense?

 

[dondada109]

I feel like maybe after a year at a lower weight I lost some of the fat cells and that might be why I only shoot up to a point then level off. Does that make sense?

I honestly don't know, and as far as I'm aware there isn't strong evidence supporting this.

However, your experience does make sense to me. Since you lost around 130 pounds and spent a significant amount of time maintaining those lower weights before moving down again, it's possible that your body gradually adjusted to those new weight ranges over time.

Maybe it's not that you're actually losing a meaningful number of fat cells, but rather that your body is becoming less inclined to defend the higher weight it used to maintain. In other words, your "set point" or settling point may have shifted downward as you spent more time at a lower weight.

Again, that's just my speculation, not something I can back up with strong evidence, but it seems like a more likely explanation than a large reduction in fat cell number