Yes, it can.latviantower said:Neither does dropping the vial.
DO NOT DROP: MECHANICAL SHOCK IN VIALS CAUSES CAVITATION, PROTEIN AGGREGATION AND PARTICLE FORMATION - PMC
Industry experience suggests that g-forces sustained when vials containing protein formulations are accidentally dropped can cause aggregation and particle formation. To study this phenomenon, a shock tower was used to apply controlled g-forces to ...
pmc.ncbi.nlm.nih.gov
...but I wouldn't worry about it too much.

