Does Tirz just ghost everyone in the end?

[JoonyO]

Gained 2lbs this week and have been 232 for 6 weeks even after adding cardio and cutting more sugar. 10mg reta and 2mg sema every 6 days....like my body just said after 15 months "were not fallin for your bullshit" frickin glucose running over 100.... im disgusted. My supply is good as the wife lost 11lbs in her first month at a ridiculously low dose. Sqwatch, im shit responder, nice to meet you.

You sound disheartened or at least frustrated.

IMO, like latviantower said, switching things up got him back on track for his goal.

We're all just RS, trying to better ourselves as we've discovered it's up to us, no one else.

Hang in there.

 

[Mara_aa]

Gained 2lbs this week and have been 232 for 6 weeks even after adding cardio and cutting more sugar. 10mg reta and 2mg sema every 6 days....like my body just said after 15 months "were not fallin for your bullshit" frickin glucose running over 100.... im disgusted. My supply is good as the wife lost 11lbs in her first month at a ridiculously low dose. Sqwatch, im shit responder, nice to meet you.

I get why you’re frustrated, it really does feel like your body just slammed the brakes.

You’ve been consistent for 15 months, and that matters way more than one stubborn stretch, it’s a hard plateau.

After this long, stalls are pretty normal. A couple of pounds can easily be water, stress, or glucose fluctuations, not fat gain. Just hang in there, it passes. Some folks stay stuck for months before things finally shift again.

 

[randompersonrandom]

I believe it’s the SURMOUNT study that showed Tirz stops weight loss around the a year to 72 weeks.

this is something that's spooking me a little bit. I started on tirz at late June of last year. I'm dragging through the last two months at six pounds from goal on a stack of 8 mg tirz and 1.6 mg Survo. I don't want to titrate up because I'm not in the mood for the fatigue that happens for a few weeks every time I do. I switched to a single vials of reta (37 mg) a week or two ago and am titrating up a little fast just so I don't have a lapse as the tirz washes out, but the only reason I'm screwing around with the reta is to check and make sure it's not something that would be awful for me so I can keep on slow hoarding it, not because I think it's the answer to finish this.

Meanwhile...did I stop the clock on the 72 weeks when I started messing around with reta? Or is the clock still running and I'm eating up my time when I should be taking advantage of still being within the time period? There's no way to know the answer because nobody tested "but what if they stop and start and switch to something that's also a glp-1 but different" and the billion variables of "randompersonrandom is fucking around."

 

[Mara_aa]

this is something that's spooking me a little bit. I started on tirz at late June of last year. I'm dragging through the last two months at six pounds from goal on a stack of 8 mg tirz and 1.6 mg Survo. I don't want to titrate up because I'm not in the mood for the fatigue that happens for a few weeks every time I do. I switched to a single vials of reta (37 mg) a week or two ago and am titrating up a little fast just so I don't have a lapse as the tirz washes out, but the only reason I'm screwing around with the reta is to check and make sure it's not something that would be awful for me so I can keep on slow hoarding it, not because I think it's the answer to finish this.

Meanwhile...did I stop the clock on the 72 weeks when I started messing around with reta? Or is the clock still running and I'm eating up my time when I should be taking advantage of still being within the time period? There's no way to know the answer because nobody tested "but what if they stop and start and switch to something that's also a glp-1 but different" and the billion variables of "randompersonrandom is fucking around."

I think “randompersonrandom is fucking around” might be the most scientifically accurate variable ever documented

At this point I’m not sure there even is a clock anymore… feels more like we all quietly left the study protocol months ago and are just freelancing it.

Jokes aside, you’re handling a pretty chaotic mix of variables and still only 6 lbs from goal, that’s honestly impressive.

Hope you find a way to close it out without triggering the fatigue boss fight again

 

[lessthanhalf]

The most common reason for feeling like the GLP drugs are no longer working is that they have caused weight loss , and you are at the new normal weight for that dose. As you lose weight metabolic rate goes down and hunger increases, so it feels like it is not working, but if weight is stable at a lower level it is working and if continued will maintain that weight loss.

I think the research on GLP drugs for BED is in its infancy, it is not really a recognised and accepted treatment yet but early research is strongly suggestive they work.

My solution was to treat high calorie / highly rewarding foods as something I just could not eat in reasonable amounts and had to totally avoid, and along with a high protein low calorific density diet got from 145kg to 75 kg and stayed there for a year, but I was still hungry most of the time, not uncontrollably so , but enough to make life a lot less pleasant. Thankfully I discovered cheap chinese GLP drugs and maintaining that weight loss is much easier with 15mg of tirz plus 5 of reta , plus more recently 0.5 of cagri as well.

 

[bbbilly]

im POSITIVE i will get hate for this. but this is my own personal experience with tirz and BED.

i lost a little over 100lbs about 11 years ago in my 20s by shear willpower and dedication. then started slowly putting the weight back on in false attempt to bulk and put muscle on. then covid shut everything down and i got laidoff several times and put back on most of it.

restarting the journey i lost somewhere around 60lbs in about 10 months and decided "why not, i qualify and i have pre diabetes, sounds like it could be easier" and it was. dropped the next 50ish pounds effortlessly by doing the same thing i did to lose the first 60, and the 100 before that.. just ignore my hunger and eat my premade meals, but this time with alot less mental pressure. when my weight slowed and stalled ill remake my meals to be a little lighter, or add more bulk (pro tip add some pre shredded coleslaw mix to stuff for a nice crunch and like 3 calories)

once i got into the normal bmi range my PCP had me stop losing as to maintain the total weight and to just get use to what i eat and how much etc for about 6 months. then the worst happened.. i lost my day job that had the health insurance that was paying for my brand name zepbound. i again went into this with the mindset of "well ill do a bulk and try to put on some muscle and enjoy the holidays" and put on 35lbs in like 4 months, then had to cut it back off... i cut 25lbs without the zep in about 3 months. then found this forum and got back on the sauce.

all that brings me to present. i take 1.25mg tirz every 7-8 days. as apposed to the 2.5mg i took to lose the 50 before. i only increased to 5 for about a month the first time i got on before the job thing happened so i didnt see anything from that. but this time im purposely spacing it a little more and using a little less specifically to feel the hunger and the food noise start coming back as a reference before i erase them. i know what to eat because i just eat what all the calorie calculators tell me to eat, and if they are a little off i adjust the last couple hundred calories but i always leave a little room for a those BED episodes i only catch when im allready in it by having the routine and have the opportunity to think "i haven't eaten something over the sink in my underwear in a while.. why am i doing it now?"

because i wasnt hungry while on tirz i had that apophony of "why am i eating when i feel so full already?" because for me its not about hunger, i just want to EAT. so when i lost access for a while i just said to myself "im not actually hungry right now, my stomach is lying to me". and would just ignore it. i eat what im supposed to eat and maybe a couple bite my wife leaves over and just go about my day.

TL R i used my time on tirz to learn my stomach is a liar and just ignore it, stick to my calories and move on, but also how to spot a BED episode when im in it and to avoid falling into one to begin with.

 

[Mara_aa]

The most common reason for feeling like the GLP drugs are no longer working is that they have caused weight loss , and you are at the new normal weight for that dose. As you lose weight metabolic rate goes down and hunger increases, so it feels like it is not working, but if weight is stable at a lower level it is working and if continued will maintain that weight loss.

I think the research on GLP drugs for BED is in its infancy, it is not really a recognised and accepted treatment yet but early research is strongly suggestive they work.

My solution was to treat high calorie / highly rewarding foods as something I just could not eat in reasonable amounts and had to totally avoid, and along with a high protein low calorific density diet got from 145kg to 75 kg and stayed there for a year, but I was still hungry most of the time, not uncontrollably so , but enough to make life a lot less pleasant. Thankfully I discovered cheap chinese GLP drugs and maintaining that weight loss is much easier with 15mg of tirz plus 5 of reta , plus more recently 0.5 of cagri as well.

That’s a really thoughtful perspective, and it makes a sense, especially the part about a “new normal” for a given dose.

Also huge respect for the weight loss and maintaining it, that’s an incredible result.

What you said about still being hungry even after doing everything “right” is exactly the part that I think many people underestimate. That’s where it feels like it goes beyond just habits.

Really appreciate you sharing all of that.

 

[Mara_aa]

im POSITIVE i will get hate for this. but this is my own personal experience with tirz and BED.

i lost a little over 100lbs about 11 years ago in my 20s by shear willpower and dedication. then started slowly putting the weight back on in false attempt to bulk and put muscle on. then covid shut everything down and i got laidoff several times and put back on most of it.

restarting the journey i lost somewhere around 60lbs in about 10 months and decided "why not, i qualify and i have pre diabetes, sounds like it could be easier" and it was. dropped the next 50ish pounds effortlessly by doing the same thing i did to lose the first 60, and the 100 before that.. just ignore my hunger and eat my premade meals, but this time with alot less mental pressure. when my weight slowed and stalled ill remake my meals to be a little lighter, or add more bulk (pro tip add some pre shredded coleslaw mix to stuff for a nice crunch and like 3 calories)

once i got into the normal bmi range my PCP had me stop losing as to maintain the total weight and to just get use to what i eat and how much etc for about 6 months. then the worst happened.. i lost my day job that had the health insurance that was paying for my brand name zepbound. i again went into this with the mindset of "well ill do a bulk and try to put on some muscle and enjoy the holidays" and put on 35lbs in like 4 months, then had to cut it back off... i cut 25lbs without the zep in about 3 months. then found this forum and got back on the sauce.

all that brings me to present. i take 1.25mg tirz every 7-8 days. as apposed to the 2.5mg i took to lose the 50 before. i only increased to 5 for about a month the first time i got on before the job thing happened so i didnt see anything from that. but this time im purposely spacing it a little more and using a little less specifically to feel the hunger and the food noise start coming back as a reference before i erase them. i know what to eat because i just eat what all the calorie calculators tell me to eat, and if they are a little off i adjust the last couple hundred calories but i always leave a little room for a those BED episodes i only catch when im allready in it by having the routine and have the opportunity to think "i haven't eaten something over the sink in my underwear in a while.. why am i doing it now?"

because i wasnt hungry while on tirz i had that apophony of "why am i eating when i feel so full already?" because for me its not about hunger, i just want to EAT. so when i lost access for a while i just said to myself "im not actually hungry right now, my stomach is lying to me". and would just ignore it. i eat what im supposed to eat and maybe a couple bite my wife leaves over and just go about my day.

TL R i used my time on tirz to learn my stomach is a liar and just ignore it, stick to my calories and move on, but also how to spot a BED episode when im in it and to avoid falling into one to begin with.

Huge respect for the level of discipline and self-awareness you’ve built.

Using tirz as a tool to understand your patterns and create that kind of structure is not something everyone manages to do.

At the same time, I think cases like yours also highlight how different BED can be from person to person. In more severe cases, it’s often tied to underlying issues that aren’t always fully resolved, so it’s not just about overriding hunger or sticking to a plan, even when you know exactly what’s happening.

Your approach is genuinely impressive and really valuable, maybe not something everyone can easily replicate?

I really appreciate you sharing your experience