Do you guys dose based on the vial or the COA?

[Rp121]

The COA for my R20 states 29.16mg which is nearly a 46% increase. Really not sure what to go by in this case as 46% seems a lot to me. But I'm a newbie to this so might be I am over-reacting. I'm planning on starting with wither 0.5 or 1.0 dose. Any advice folks?

 

[Dos-Dox]

The COA for my R20 states 29.16mg which is nearly a 46% increase. Really not sure what to go by in this case as 46% seems a lot to me. But I'm a newbie to this so might be I am over-reacting. I'm planning on starting with wither 0.5 or 1.0 dose. Any advice folks?

I’d use the COA value. Better to underdose than overdose, especially when you’re first starting out. I’d start with 0.5 mg and hold that for a few weeks. (I personally started at 0.25 just to assess tolerability and then went to 0.5 mg for weeks.) Some want to titrate up to the clinical trial starting point of 2 mg as quickly as possible or start there immediately, but my philosophy is to be patient and work up slowly so you let your body adjust and don’t get hit with all the sides. Good luck!

 

[Rp121]

I’d use the COA value. Better to underdose than overdose, especially when you’re first starting out. I’d start with 0.5 mg and hold that for a few weeks. (I personally started at 0.25 just to assess tolerability and then went to 0.5 mg for weeks.) Some want to titrate up to the clinical trial starting point of 2 mg as quickly as possible or start there immediately, but my philosophy is to be patient and work up slowly so you let your body adjust and don’t get hit with all the sides. Good luck!

Thanks Dos-Dox. Your advice mirrors that from another on a separate forum I'd posed the question. I'm in no rush to titrate either. Slow and steady for me too. I'm nervous but really excited. I hope this works. I've been overweight/obese all my life despite trying a lot in terms of gyms, diets etc. Thanks again for your tips.

 

[wildcat0367]

FWIW, I am only a few months in to this, coming from branded Mounjaro. So far, I have dosed based on the coa. If I were to feel as if it was underdosed or something, I would probably revert to the vial mg. I am still @ 5mg Tirz currently and buying T30. IME so far, the gray market stuff has "felt" stronger than the Lily stuff.

If it is over or under 10% of label I will adjust dosage otherwise I just dose according to label contents.

 

[Tron Carter]

COA usually. Especially if there was any group testing and they look to be pretty consistent.

 

[Twowheelr2]

Im used to taking 5mg, triz from the white market. I purchased some 30mg vials, but the COA says 33.68mg. Should I use it with the assumption its 30mg or 33.68mg?

I haven’t seen any measured volume or weight from any source to be exact. Pharmacy, compound pharmacy or internet venders. Even vials from the same batch have different values. If you’re concerned, go low.

 

[HereKittyKitty]

I dose based on the CoA tested mass.

I have a 50mg kit that tested at 62+mg. I cannot imagine the harm I could do if I followed the "label" mass.