Day 3 of Selank and blown away

[Zydeceltico]

Yeah, controlling social anxiety us one of its main uses. I have a long history with alcohol and Reta helped me stop completely. I started it to lose weight, but even 1 mg eliminated any desire I had for alcohol. Social gatherings just mean I have some Sprite or seltzer with a lime and no one cares. Someone can drink in front of me now and it's the same as watching paint dry. I think I will always be on it for that reason alone. Great job staying sober for 6 months. One day at a time.

For Selank and Semax, there are several advertised benefits. I use this site as a frequent source because it's continuously updated and has updated protocols. https://pep-pedia.org/

Best of luck on your journey.

Same happened for me. When I started tirz at the beginning of June of 25, I already had 12 months of sobriety and was doing fine - however - and understandably - there would still be urges from time to time and I had been a smoker for years also. On July 28, 2025 I must of tripped a breaker because not only did all "urges" vanish, I also just cold-turkey quit smoking without any issue whatsoever. I'll stay on the T for that reason alone also. It's a trip...and I am grateful.

 

[jw717us]

I'm about to give selank and semax a try, i'm always overthinking and my short memory is fucked, i have a drug abusing background, too much alcohol, mdma, cannabis, ecstasy in my 20s, tried to compensate my childhood trauma through all the drug using. i had panic attacks 4/5 years ago which lasted almost 2 years, felt like a heart attack every day, got to the cardiac doctor but everything was fine, are these two repairing the nerves/wiring in the brain? So would the benefits/effects lasting even after stop taking these two compounds?

From my reading to prep for research yes. There is substantial evidence from Russian/eastern-European studies, and practical evidence from prescribed patients, that Selank has a long term effect.

From my research myself I have seen the impact dramatically. The short term impact is to calm the misfiring and dampen the stress response by "enhancing inhibitory GABAergic signaling and modulating the HPA axis, which can blunt the intensity and duration of fight or flight activation. "

That initial stress response that one overreacts to is just quiet. Research here has shown an overall calming effect, worries become manageable thoughts in the background rather than things that must be addressed right now.

I liken it to the one Taylor Tomlinson from one of the more recent Netflix specials. She discusses other people having feelings that walk up to be felt with and those people being able to say "Yes, I know you want to be felt but just not right now..... AND THAT WORKS FOR THEM". Massively paraphrasing here but that's the gist.

Not observing sedation, or lack of drive in any way. I can focus on what I want to focus on without the constant "prep for worst case scenario on these 40 things" going on in the back of my brain.

 

[jw717us]

They are supposed to have on going residual effects. Sorry to hear what you've been through. I know all about childhood trauma. Check out Selank and also Adalank, an NA version of Selank. Adalank is suggested for PTSD and GAD and is an enhanced version of Selank. I would start with Selank first and see what that does for you.

I've read on NA and Adalank but everything I have found show they are theoretical and I have not located any supporting studies. Selank is relatively cheap and widely available....and it is thoroughly studied outside of the US with impactful results. I'm having trouble (personally) seeing the need for the added cost, sourcing inconvenience, for questionable upside.

Have you found anything concrete on those? If you have please point to it. If there is more there I would definitely reconsider the pros/cons!

 

[cheaperseeker]

Thanks for your kind words guys appreciate it, does it also help for social anxiety? I always used alcohol for this, to get socially open really weird it worked but in retrospective i should have faced my fears because this shit fucked up my whole mindset, stopped alcohol for 6 months now and its really hard to connect with people at partys or even meetings, i'm also doing my master for plumbing this year, it was the main reason why i looked at semax and selank because i'm out of school for like 11 years haha

I have social anxiety too. When I have a social event, I pin 500 mcg each of Selank and Semax, then take 400 mg of L-theanine. They work best for me when I only use them as needed, not regularly. BTW, if you get coffee jitters, L-theanine works great to counteract them.

 

[cheaperseeker]

I have social anxiety too. When I have a social event, I pin 500 mcg each of Selank and Semax, then take 400 mg of L-theanine. They work best for me when I only use them as needed, not regularly. BTW, if you get coffee jitters, L-theanine works great to counteract them.

Oh, and some people get drowsy from L-theanine. It doesn't affect me that way at all, but if you've never tried it before, I'd test it with 200 mg on a day you're not doing anything else.

 

[Chili777]

I've read on NA and Adalank but everything I have found show they are theoretical and I have not located any supporting studies. Selank is relatively cheap and widely available....and it is thoroughly studied outside of the US with impactful results. I'm having trouble (personally) seeing the need for the added cost, sourcing inconvenience, for questionable upside.

Have you found anything concrete on those? If you have please point to it. If there is more there I would definitely reconsider the pros/cons!

No, just anecdotal evidence and my own peptide appetite, I will freely admit. If Selank is good, stronger is better. Most RSs that have used them like the intensified effects. I do think that if someone has GAD or PTSD it would be well worth investigating. As for cost and convenience, it may not be worth it to someone who doesn't experience those issues.

I have NA Semax on order and will post my experience when I start my next cycle.

 

[jw717us]

I have NA Semax on order and will post my experience when I start my next cycle.

Please do. I would love to hear it. I sourced a few vials for initial testing but plan to look into full kits. That would be the time to make the shift.

 

[pddz9]

Yeah, controlling social anxiety us one of its main uses. I have a long history with alcohol and Reta helped me stop completely. I started it to lose weight, but even 1 mg eliminated any desire I had for alcohol. Social gatherings just mean I have some Sprite or seltzer with a lime and no one cares. Someone can drink in front of me now and it's the same as watching paint dry. I think I will always be on it for that reason alone. Great job staying sober for 6 months. One day at a time.

For Selank and Semax, there are several advertised benefits. I use this site as a frequent source because it's continuously updated and has updated protocols. https://pep-pedia.org/

Best of luck on your journey.

Yeah it's not like i can't speak to people but often when i do, to people i havent met a long time i get nervous and think like "what are they thinking of me?" "What should i say?" "Is it weird when i say this or that?" or if someone is doing fun off me i dont know how to react,I wasn't like that, normally i laughed it off and gave them some joking answer back i think the drugs did a good job and slowly fucked me up, yeah thank you

 

[wildcat0367]

It's quite amazing really! All you needed was a small peptide to win you over.

'Functional high anxiety' oh I like that one. I'm the proto-type lol.

I don't know about the long term remodeling, but we'll find out.

My job is really often stressful and a lot of quick decisions, - a tiny bit of selank in the daytime helps a lot together with semax. And Selank before sleep too, my body feels like a gummi bear. ;-)

I used to do subkutaneous inj, not really convincing effect, but then I made som nasal sprays = OMFG it's working lol

You are correct, tried both myself and the nasal spray works about 10 times better than sub q.

 

[Foggy-Hollow]

That's so great !

I know about denial or just not knowing. I'm a medical doctor, and I didn't realize until I was 42 that I have anxiety. It just didn't occur to me, until my GP said it. I was like : no you are mistaken ! ' So what do you think those symptoms are ?' lol

But I also didn't realize, I'm ADD until 47 or 48, because I was always told : no one goes through medical school if they have ADD/ADHD. No one has those jobs and do those functions with ADD/ADHD. Well, I do have A LOT of co worker with that or autism. So common in my profession.

Anxiety is just one of the most common feelings / disorders, and it comes it so many forms and shapes.

I do have selank, and it shuts my brain up too.

ADHD dx at 47 (if I remember?).

If you haven’t dug into it the estrogen - serotonin connection is interesting. Estrogen drops, so serotonin drops, and then executive function is negatively affected. Previously mostly-coping females go through menopause transition and life falls apart. I clawed my way to my engineering degree, now I know a good part of why. My new industry had more neuro-spicy types, it’s been interesting in a good way.

And the anxiety-Depression-serotonin connection is in there too.

I am convinced we are chemical soup! So much is interconnected.

Still haven’t ordered anything since my pens… selank is still on my short list.

 

[Chili777]

I've read on NA and Adalank but everything I have found show they are theoretical and I have not located any supporting studies. Selank is relatively cheap and widely available....and it is thoroughly studied outside of the US with impactful results. I'm having trouble (personally) seeing the need for the added cost, sourcing inconvenience, for questionable upside.

Have you found anything concrete on those? If you have please point to it. If there is more there I would definitely reconsider the pros/cons!

I did some searching and it appears that NA Semax has had clinical research studies performed and it is approved for use in Russia, so roughly on par with standard Semax. I found this article which also includes a couple links to published research. Just ignore the sales ads since this appears to be a US vendor.

https://aminousa.com/n-acetyl-semax-amidate-vs-semax-understanding-the-differences

 

[jw717us]

I did some searching and it appears that NA Semax has had clinical research studies performed and it is approved for use in Russia, so roughly on par with standard Semax. I found this article which also includes a couple links to published research. Just ignore the sales ads since this appears to be a US vendor.

https://aminousa.com/n-acetyl-semax-amidate-vs-semax-understanding-the-differences

Much appreciated! I’ll look at this tomorrow.

 

[Peptidesearch]

Interesting stuff, I'm off to watch some YT vids on it.

 

[Chili777]

I also found an article with citations to Russian clinical research on N-Acetyl Selank as well. The research can be further investigated by those interested. Both NA versions are approved and available by prescription in Russia.

N-Acetyl Selank Studies on Cognitive Impact

N-Acetyl Selank is an acetylated form of the heptapeptide Selank. Selank is a synthetic analog of the natural tetrapeptide tuftsin (threonine - lysine - proline - arginine).

biotechpeptides.com

It's appears, after all this reading, that both NA versions of Semax and Selank have all the same neurological benefits of the standard versions but offer higher bioavailability and an increased half-life, so require slightly smaller doses for the same efficacy. Damn, now I need to make another order for NA Selank.

 

[miss-sanne]

ADHD dx at 47 (if I remember?).

If you haven’t dug into it the estrogen - serotonin connection is interesting. Estrogen drops, so serotonin drops, and then executive function is negatively affected. Previously mostly-coping females go through menopause transition and life falls apart. I clawed my way to my engineering degree, now I know a good part of why. My new industry had more neuro-spicy types, it’s been interesting in a good way.

And the anxiety-Depression-serotonin connection is in there too.

I am convinced we are chemical soup! So much is interconnected.

Still haven’t ordered anything since my pens… selank is still on my short list.

Yeah, estrogen levels can really mess up around menopause.

I always thought i was gonna be 50 and take a shower in estrogen.

But several breast cancers appeared in both close family and other family, so that door is closed now.

The last few days its been ever better after work. My work is very busy and quite stressful, many interactions, 'difficult patients' (in general practice), usually I'm so tired and flat when I come home. But Semax and Selank really helps with that

 

[dk2001]

I came here today searching for this topic! I've been using standard semax for a couple months. I tried nasal spray first and it did nothing for me. I started pinning at 200 mcg and eventually moved up to 2 mg and my focus is great. I know that seems like a lot but lower dose does nothing. I was thinking of trying the NA version to see if I get better results and now thinking I should add Selank. I do not struggle with anxiety though. I sleep pretty well most nights my issue is all focus. Would it still be helpful to add selank? If so, is selank taken in the evening or would i take both in the morning at the same time?

 

[Foggy-Hollow]

Yeah, estrogen levels can really mess up around menopause.

I always thought i was gonna be 50 and take a shower in estrogen.

But several breast cancers appeared in both close family and other family, so that door is closed now.

The last few days its been ever better after work. My work is very busy and quite stressful, many interactions, 'difficult patients' (in general practice), usually I'm so tired and flat when I come home. But Semax and Selank really helps with that

I’m so sorry to hear about the cancers. I’m glad you’re taking care of yourself.

“I’m sold” you should be commissioned here. The adhd has been changing in a way, coming off from bupropion ( with doc’s go-ahead). Not in an unexpectable way. Maybe February I will try.

 

[miss-sanne]

I’m so sorry to hear about the cancers. I’m glad you’re taking care of yourself.

“I’m sold” you should be commissioned here. The adhd has been changing in a way, coming off from bupropion ( with doc’s go-ahead). Not in an unexpectable way. Maybe February I will try.

You go for it ! do the nasal, and write, how it goes

 

[Chili777]

I came here today searching for this topic! I've been using standard semax for a couple months. I tried nasal spray first and it did nothing for me. I started pinning at 200 mcg and eventually moved up to 2 mg and my focus is great. I know that seems like a lot but lower dose does nothing. I was thinking of trying the NA version to see if I get better results and now thinking I should add Selank. I do not struggle with anxiety though. I sleep pretty well most nights my issue is all focus. Would it still be helpful to add selank? If so, is selank taken in the evening or would i take both in the morning at the same time?

Did you buy the Semax already reconstituted for nasal use? Do you know what the concentration was? I mixed my own, so two sprays provides 1 mg. I take Semax IN in the mornings just before work, along with my usual cup of coffee, and I'm set for the day. I like it so much I have NA on the way.

I've read Selank is more of an anytime peptide for anxiety and used in the morning for It's cognitive benefits.

 

[Peptidesearch]

Yeah, estrogen levels can really mess up around menopause.

I always thought i was gonna be 50 and take a shower in estrogen.

But several breast cancers appeared in both close family and other family, so that door is closed now.

The last few days its been ever better after work. My work is very busy and quite stressful, many interactions, 'difficult patients' (in general practice), usually I'm so tired and flat when I come home. But Semax and Selank really helps with that

I've been reading the risk is lower than previously thought.

Breast cancer risk model provides reassuring data for those with family history of disease after short-term HRT use

Hormone replacement therapy taken at age 50 for up to 5 years only modestly increases the risk of breast cancer, even for women with a strong family history of the disease, according to a new risk model published in the British Journal of General Practice .

Breast cancer risk model provides reassuring data for those with family history of disease after short-term HRT use

Breast cancer risk model provides reassuring data for those with family history of disease after short-term HRT use

www.icr.ac.uk