从替泽帕肽换成瑞他肽……即使是中等剂量，效果也不明显。

[GuLPing]

发帖是想听听大家的意见。我买到的肽效价会不会是低效的？

我之前用替泽帕肽减了30磅，而且剂量并不大。最后，我每周只用6毫克。这种肽对抑制食欲、减少食物噪音甚至啤酒摄入量都很有帮助（两品脱啤酒我就喝不下了）。后来

我换成了瑞他肽，一开始每周3毫克。一个月后，我把剂量增加到每周6毫克。我的体重基本保持稳定。我感觉精力更充沛了，所以开始锻炼，但似乎效果不明显。有没有其他人也经历过类似的情况，可以分享一下从替泽帕肽换到瑞他肽的剂量建议？|

我有点怀疑我买到的肽是不是有问题。供应商（我就不点名了）回复很及时，而且口碑也不错，所以我猜应该不是肽的问题。

大家有什么看法吗？

 

[lhenderdon]

一年后，我服用Tirz的剂量达到了12.5毫克的上限，减重83磅后体重就停滞不前了。

我改用Reta，剂量为5毫克，结果三周后体重反而增加了2磅，而且

食欲完全没有抑制。我逐渐增加剂量到7毫克，食欲抑制效果也微乎其微。

之后我又加了0.5毫克的Cagri，食欲抑制效果又回来了，而且第一周就减掉了那2磅

。就我个人而言，我对Reta的感觉很复杂，虽然体重似乎

在下降，但速度很慢，即使在最好的情况下，每周也只能减掉0.5到1磅。

 

[ZippityDooDah]

你为什么换药？

我服用Tirz两年多了，除了最初的7个月左右，其他时间都是15毫克的剂量。2024年底，因为停药两个多月，我才停药。停药后

我休息了三个月，今年四月开始服用Reta。由于Reta对我没有任何效果，我迅速增加了剂量。第四次服用时，我尝试了12毫克，终于又找到了感觉。我知道我用的产品是好的（实际上，测试中平均每瓶的剂量略高于13毫克），所以我只需要找到身体真正能产生反应的剂量。

总之，不断增加剂量，直到见效为止。

 

[GuLPing]

After a year I was at the max 12.5 mgs of tirz and stalled after loosing 83lbs.

I switched to Reta at 5mgs and actually gained 2lbs after 3 weeks and had

zero appetite suppression. I titrated to 7 mgs and had minimal suppression.

I have since added .5mgs cagri and the suppression was back lost the 2 lbs

that 1st week. Personally I have mixed feelings about Reta it seems the weight

is going down but slowly at .5 to 1lb on a good week.

What's Cagri? The nice thing for me is that I have wya more energy on this. The blood sugar lowering effects of it seemed to make me tired. That said, I might have the same when I up the dose of this stufff.

Why did you change?

I was on tirz for just over 2 years, at the full 15mg for all but the first ~7 months before I stopped at the end of 2024 due to an 2+ month stall.

I took about 3 months off and started reta this past April. I rapidly escalated my dose since it wasn't doing anything for me, and my 4th dose I tried 12mg and finally found the magic again. I knew the product I had was good (actually averaged a little over 13mg/vial in testing), so I just had to find the point where my body would actually respond.

Bottom line, keep going up until something happens.

That makes a lot of sense. I think I'm going to up to 8mg. Obviously there's no 3rd round research out yet but it seems like if you're on a mid dose of T you need a mid dose of R.

 

[lostlakebear]

Why did you change?

I was on tirz for just over 2 years, at the full 15mg for all but the first ~7 months before I stopped at the end of 2024 due to an 2+ month stall.

I took about 3 months off and started reta this past April. I rapidly escalated my dose since it wasn't doing anything for me, and my 4th dose I tried 12mg and finally found the magic again. I knew the product I had was good (actually averaged a little over 13mg/vial in testing), so I just had to find the point where my body would actually respond.

Bottom line, keep going up until something happens.

Is a break typically suggested when changing peptides? I am planning to go from tirz to reta soon. I haven't maxed out tirz yet, I am at 7.5mg, but reta is sounding superior. Thanks.

 

[Batscout]

What's Cagri? The nice thing for me is that I have wya more energy on this. The blood sugar lowering effects of it seemed to make me tired. That said, I might have the same when I up the dose of this stufff.

That makes a lot of sense. I think I'm going to up to 8mg. Obviously there's no 3rd round research out yet but it seems like if you're on a mid dose of T you need a mid dose of R.

Cagri is Cagrillintide. You can find out quite about it by searching this forum.