Sorry, I cannot post the url due to my posting restriction but check CNN for the article!
Orforglipron, named brand Foundayo, is made by Eli Lilly. As part of the deal, medicare would also cover the pill for some patients, with a monthly under $50, starting as soon as July 1.
In a trial supporting approval, people on the highest dose of Foundayo lost an average of 12% of their body weight over 72 weeks, compared with 0.9% for people taking a placebo. The injectable drugs have produced weight loss in trials of more than 20%, while Novo Nordisk said the Wegovy pill showed average weight loss of up to 17% on the highest dose in trials.
The pills also represent a major change in pricing of and access to GLP-1 drugs; in a deal struck with the administration in November, the pills start at $149 a month at the lowest doses for patients paying out of pocket, a much lower price than had previously been available.
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In my ignorant opinion, pill-based might make it easier and less expensive to manufacture and distribute. Perhaps also flatten out the peaks seen with weekly Zepbound injections. Would be great as a maintenance med when millions have done their heavy weight loss and need a smaller boost to just keep the weight off.
Orforglipron, named brand Foundayo, is made by Eli Lilly. As part of the deal, medicare would also cover the pill for some patients, with a monthly under $50, starting as soon as July 1.
In a trial supporting approval, people on the highest dose of Foundayo lost an average of 12% of their body weight over 72 weeks, compared with 0.9% for people taking a placebo. The injectable drugs have produced weight loss in trials of more than 20%, while Novo Nordisk said the Wegovy pill showed average weight loss of up to 17% on the highest dose in trials.
The pills also represent a major change in pricing of and access to GLP-1 drugs; in a deal struck with the administration in November, the pills start at $149 a month at the lowest doses for patients paying out of pocket, a much lower price than had previously been available.
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In my ignorant opinion, pill-based might make it easier and less expensive to manufacture and distribute. Perhaps also flatten out the peaks seen with weekly Zepbound injections. Would be great as a maintenance med when millions have done their heavy weight loss and need a smaller boost to just keep the weight off.
