anyone else getting considerably better results with Tirz compared to Reta?

[FlowerFairy]

This is kinda what I didn’t want to hear

Coming off a 13 month tirz journey, last few months was at 15mg and nothing happening. Still have a fair bit to lose.

Tirz is still in my system but Last week started pinning Reta. 2mg ( split dose) so far I have noticed I am thinking about sweet things again when that has been totally absent for almost a year. I do still have suppression but it’s different.

All things need time to be tested out fully, one change at a time ( so you know what works) going to follow my own advice and go low and slow with the reta titration. Because there is nowhere else to go if Reta doesn’t work for me.

Not true. There is always “ghetto Reta”- Tirz plus Survo or maz.

 

[Calm Logic]

And there is always ghetto tirz, haha, which I guess could be tirz + sema (a combo already mentioned above).

 

[keangkong]

I have found great success with using Tirz + increased cardio + habits I already had in previous cuts. it was much easier than any cut I've ever done before, other than harsh metabolic sides for the first few weeks. Tirz rocks. this was November 2024 until about March 2024.

around that time I was transitioning to maintenance and decided to get some Reta. the mechanism appears to be strictly better and research shows greater weight loss.

well, after months of playing with dosages, I have concluded that with Reta compared to Tirz:

I get much weaker apppetite suppression

it makes me more likely to binge (an old habit) and less likely to stop mid-binge and question myself

skin sensitivity is a serious problem. with Tirz it was negligble

I feel less energetic overall

on multiple occasions I have done A/B testing with Tirz, specifically right now. I think I've taken a total of 6mg Tirz in the span of almost two weeks. appetite suppression is just so much stronger, it's ridiculous - with Reta I'm not getting that at 8mg. it feels like I can choose to eat, or can choose not to, and my body doesn't care one way or the other (though I still enjoy the act of eating... old habits die hard)

sorry if that was a little long, but anybody else experiencing something like this? shouldn't Reta be better?

I think you're experiencing something fairly common: Some medicines work more powerfully in some. I had better weight loss on reta but needed to stop because on it my liver enzymes were rising higher than they ought to be. Back to tirz.

 

[meeklady]

This is kinda what I didn’t want to hear

Coming off a 13 month tirz journey, last few months was at 15mg and nothing happening. Still have a fair bit to lose.

Tirz is still in my system but Last week started pinning Reta. 2mg ( split dose) so far I have noticed I am thinking about sweet things again when that has been totally absent for almost a year. I do still have suppression but it’s different.

All things need time to be tested out fully, one change at a time ( so you know what works) going to follow my own advice and go low and slow with the reta titration. Because there is nowhere else to go if Reta doesn’t work for me.

I had normal appetite until 6 mg. 8 mg is where I lost all the weight and had zero appetite! It's just a case of finding the dose which works for you.

 

[Calm Logic]

The problem, apparently, is getting there, which is why people bust out the cagri, sema, etc.

If going from tirz to reta, it often seems to be a mistake to stop tirz completely.

 

[Rejuvenateme000!]

The problem, apparently, is getting there, which is why people bust out the cagri, sema, etc.

If going from tirz to reta, it often seems to be a mistake to stop tirz completely.

I'm starting reta today, but I'm going to keep tirz too. I have to control the hunger.

 

[Airborne Daddy]

I have found great success with using Tirz + increased cardio + habits I already had in previous cuts. it was much easier than any cut I've ever done before, other than harsh metabolic sides for the first few weeks. Tirz rocks. this was November 2024 until about March 2024.

around that time I was transitioning to maintenance and decided to get some Reta. the mechanism appears to be strictly better and research shows greater weight loss.

well, after months of playing with dosages, I have concluded that with Reta compared to Tirz:

I get much weaker apppetite suppression

it makes me more likely to binge (an old habit) and less likely to stop mid-binge and question myself

skin sensitivity is a serious problem. with Tirz it was negligble

I feel less energetic overall

on multiple occasions I have done A/B testing with Tirz, specifically right now. I think I've taken a total of 6mg Tirz in the span of almost two weeks. appetite suppression is just so much stronger, it's ridiculous - with Reta I'm not getting that at 8mg. it feels like I can choose to eat, or can choose not to, and my body doesn't care one way or the other (though I still enjoy the act of eating... old habits die hard)

sorry if that was a little long, but anybody else experiencing something like this? shouldn't Reta be better?

I do 1mg of sema with 8mg reta every 5 days when I run reta... helps alot with hunger suppression

 

[Thistley]

I had normal appetite until 6 mg. 8 mg is where I lost all the weight and had zero appetite! It's just a case of finding the dose which works for you.

Thank you @meeklady how did you do schedule your titration up to 8?

started with 2mg reta last week and I have put on 2lbs this week

 

[BooneDonk]

Thank you @meeklady how did you do schedule your titration up to 8?

started with 2mg reta last week and I have put on 2lbs this week

Reta happy place for me now is 4mg every 3 days. I’m on roughly week 3 of this and where my body is happy. The (a-word skin discomfort word even my phone can’t autocorrect for me) is MUCH more tolerable than 6mg weekly or 5mg every 5 days oddly. I think it’s the spike on pinning that made that bad for me fwiw.

 

[keangkong]

Reta happy place for me now is 4mg every 3 days. I’m on roughly week 3 of this and where my body is happy. The (a-word skin discomfort word even my phone can’t autocorrect for me) is MUCH more tolerable than 6mg weekly or 5mg every 5 days oddly. I think it’s the spike on pinning that made that bad for me fwiw.

I believe my chances of having allodynia is much higher than the general population due to me having autism. No, I don't have allodynia. I may find a particular fabric annoying or painful, or my find some contact with my skin painful, but no more than people in general do. I didn't have it when I was taking retatrutide.

 

[BooneDonk]

I believe my chances of having allodynia is much higher than the general population due to me having autism. No, I don't have allodynia. I may find a particular fabric annoying or painful, or my find some contact with my skin painful, but no more than people in general do. I didn't have it when I was taking retatrutide.

The tone of your replies makes a lot of sense now! Not that I ever took offense, but some have. I like it. Direct and to the point! I do get the skin crawlies, reminds me of gout pain in the big toe but on my thighs and back and chest. Lovely feeling.

While I do not have autism, OCD is a MF. I’ll be back after I make sure the silverware is straightened in the drawer. (I kid, I put it up this am. I know it’s done correctly. )

 

[keangkong]

The tone of your replies makes a lot of sense now! Not that I ever took offense, but some have. I like it. Direct and to the point! I do get the skin crawlies, reminds me of gout pain in the big toe but on my thighs and back and chest. Lovely feeling.

While I do not have autism, OCD is a MF. I’ll be back after I make sure the silverware is straightened in the drawer. (I kid, I put it up this am. I know it’s done correctly. )

Sorry for having a tone that bugs people at times. I do care about people and try not to be offensive. But some things I do will offend people. I do like this forum for its directness. Although I'm on the Meso board too, I frequently have to skip over the chest thumping. I'm not a big fan of arguing where the point is to either offend or to win at all costs. I do wish I had a little bit of OCD; it would help me be more organized. (I say that tongue in cheek; I know that that having it would be tough.)

 

[BooneDonk]

Sorry for having a tone that bugs people at times. I do care about people and try not to be offensive. But some things I do will offend people. I do like this forum for its directness. Although I'm on the Meso board too, I frequently have to skip over the chest thumping. I'm not a big fan of arguing where the point is to either offend or to win at all costs. I do wish I had a little bit of OCD; it would help me be more organized. (I say that tongue in cheek; I know that that having it would be tough.)

No offense here. Keep it real!

 

[keangkong]

No offense here. Keep it real!

I much prefer people who keep it real. Be happy. Be sad. Be angry. Laugh or don't laugh. But keep it real.

 

[meeklady]

Thank you @meeklady how did you do schedule your titration up to 8?

started with 2mg reta last week and I have put on 2lbs this week

I followed the titration schedule of 4 weeks for each dose until I got to 8 mg. I started to notice less food noise at 6 mg but the real magic happened at 8. I lost 30 lbs at 8 mg ( over about 8-10 weeks) and now at goal weight so trying to find the right maintenance dose now.

Trust the process and it will finally happen. Believe me, I was starting to lose hope during the first few months but am happy I persisted.

 

[Bsqueezin]

Evrything I’ve read and heard is that Reta appetite suppression is nowhere near that of Tirz, Sema, or Cag.

I’ve started on Reta and definitely feel some suppression, but definitely resonate with still feeling hungry

I'm doing 8mg / week if reta and the food noise is non existent. I have to force myself to eat and even then it's extremely small amounts. I never tried tirz though, I went from semaglutide to reta and skipped the tirz. I honestly started at 4mg and did that for 2 weeks and then went straight to 8mg. I had been doing the 2.5 semaglutide for a little over a year and hit a huge plateau.

 

[ConnieL]

Not true. There is always “ghetto Reta”- Tirz plus Survo or maz.

What does Maz and Survo do? I heard something about them and have been curious. I am 2.5mg of Reta I started low to avoid flu like symptoms I had with larger doses if Tirz. Overall, I am losing slow and that is okay. My issue lately has been "food noise". I don't sleep well and the last couple weeks I have been getting food to snack on. I have thought I might add some Tirz or Cag. Any thoughts you might want to share. Being on Reta has helped with inflamation issues.

 

[Garbo]

I chose Reta since it’s supposed to be better than tirz but I do kind of miss it. But my freezer stash won’t even let me consider it again lmao

You and your sweet little Tasmanian devil are doing great but ohhhhh, I hate that you are having to battle so hard – the fatigue, the lack of your former motivation to work out ... and that most dread scourge, the one I personally have shockingly little patience for: " slow weight loss."

All of which is to say, you don't have to let your freezer stash of Reta stop you from trying something you would otherwise try.

This is the gray market, and there's always a way for you to do what you want to do.

Don't have the spare cash to buy Tirz? TRADE Reta for some! Not sure Tirz will help you anyway? Just get a vial or two to start out!

So many of us have stocked up on one peptide only to find at some point that we wanted/needed/were tempted to go in another direction.

There are probably people on this forum right now who have years' worth of Tirz in their freezer, but have switched to Reta. There are trustworthy small resellers among us who will ship you a half-kit for relatively little money.

If you think there's a chance that Tirz might make your life a little easier and your weight loss a little faster .... I hope you will consider giving yourself the opportunity to find out. You have earned it and you deserve it.

Hug that little devil of yours for me, and give his mommy the break she deserves

 

[CrimsonTaco47]

You and your sweet little Tasmanian devil are doing great but ohhhhh, I hate that you are having to battle so hard – the fatigue, the lack of your former motivation to work out ... and that most dread scourge, the one I personally have shockingly little patience for: " slow weight loss."

All of which is to say, you don't have to let your freezer stash of Reta stop you from trying something you would otherwise try.

This is the gray market, and there's always a way for you to do what you want to do.

Don't have the spare cash to buy Tirz? TRADE Reta for some! Not sure Tirz will help you anyway? Just get a vial or two to start out!

So many of us have stocked up on one peptide only to find at some point that we wanted/needed/were tempted to go in another direction.

There are probably people on this forum right now who have years' worth of Tirz in their freezer, but have switched to Reta. There are trustworthy small resellers among us who will ship you a half-kit for relatively little money.

If you think there's a chance that Tirz might make your life a little easier and your weight loss a little faster .... I hope you will consider giving yourself the opportunity to find out. You have earned it and you deserve it.

Hug that little devil of yours for me, and give his mommy the break she deserves

That was the sweetest message, thank you this morning…this last month if I’m being honest, has been so tough and your words of kindness and wisdom mean so much. Thank you

 

[FlowerFairy]

What does Maz and Survo do? I heard something about them and have been curious. I am 2.5mg of Reta I started low to avoid flu like symptoms I had with larger doses if Tirz. Overall, I am losing slow and that is okay. My issue lately has been "food noise". I don't sleep well and the last couple weeks I have been getting food to snack on. I have thought I might add some Tirz or Cag. Any thoughts you might want to share. Being on Reta has helped with inflamation issues.

Max and Survo are more like Reta- I don’t know much about Max, but I have been trying Survo with Tirz. Supposedly they offer better food noise suppression vs Reta, but I’m one of those folks who never had much food noise on any of the GLPs.