AI scans 400,000 Reddit posts to flag overlooked GLP-1 side effects

[Grogu]

Can someone with paywall access kindly post the whole original article or link to it?

Here is the paywall abstract: https://www.nature.com/articles/s44360-026-00108-y

The institution where I work only subcribes to a couple of years of this journal, but the authors have posted a copy of the paper here:

Self-Reported Side Effects of Semaglutide and Tirzepatide in Online Communities

Social media can reveal patient experiences with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) that extend beyond clinical trial data. We analyzed 410,198 Reddit posts (May 2019-June 2025) mentioning semaglutide or tirzepatide. A total of 67,008 users self-reported using these...

arxiv.org

Top right hand corner says "Access Paper"

The abstract is the same as the one posted upthread. So, I'm sure it's the same paper

 

[Sasquatch]

What the fuck is Reddit?

 

[JFinHK]

It's very likely to be due to the fact that abdominal fat has a major role in hormone production/regulation...it disrupts sex hormones. So I can imagine if all that fat was reduced fast....But also, it would be interesting to see how many of those who reported changes in menstrual cycle were actually peri- or menopausal. That's a whole other pot of hormonal issues.