6 weeks on Reta, and surprising result.

Status
Not open for further replies.
ultima thule said:
It is my 6th week on Reta now, and it was so far so good....but as every Friday morning I checked my weight today and boom! Surprise! So I started from 1mg per week. On the 3rd week tirtrated to 2 mg. Results were just perfect, cuz my weight was dropping 1.5kg/3.3lbs per week average. But today, when I stepped on weight scale it shows 0.5kg/1.1lbs more, than the week before. 🫤 So I tried to figure out, if anything changed in my routine the last week. First thing is Epithalon, I started a week ago (0.5mg/day), and the second, I add a bit more protein to my daily intake (around 30g). Don't think that any of those had any impact on gaining within last week. All of the rest is, as it was beforehand. 5 days a week at the gym, high protein/low carb/low fat diet, 2 meals per day, sleeping well, around 7h...I'm a bit confused, cuz Reta shot day is Monday and wanted to titrate to 3mg this time, but reading now alot about the magic threshold of the 4mg of Reta, and considering to jump on that dose now. And btw, food noise, feeling full while eating, no cravings, those all are working fine. Also have no side efects at all on 2mg. So at first, wondering, why I gained in the 6th week on Reta, and what dose would you recommend for me to jump on now. Or maybe stay on 2mg and see what will happen?
I would suggest that you don't chase the scale number with dosing. Give it at least two weeks. If it doesn't resolve by then and start showing trend down then move up. A plateau doesn't necessarily mean your body is done. I will note that 30g extra protein is 150+ calories per day, depending on the source. I doubt that would tank you, but I would think it could possibly cause a pause while your body is adjusting. There are so many variables, and many things we don't even track or think about. Yet another reason to not chase scale numbers with dosing. One other note, is this the same vial of Reta you started with 6 weeks ago? I used a vial on my wombat for 8 weeks and when I mixed a new on could tell clearly that the old vial had degraded in effectiveness (huge difference in appetite and plateau resolved). It was night and day. The stuff I've seen in testing shows after a month the degradation is real. My "test" confirmed it.
 
px1984 said:
I would definitely consider weighting every morning and sticking in an app, I can fluctuate 0.5kg on my scales in a day. This prevents you weighing one week at an abnormal low and then happen to hit the next week well hydrated on a full stomach. Then it’s about tracking trends.

I also weight three times and make sure they are about the same.
I agree! I weigh every day, but don't put any stock into that number. It's just to see a clear trend in weekly averages. I have seen 5lb fluctuations morning to morning. The body is a crazy thing. It also helps to weight at the same time, same situation (after bathroom, before eating, etc.). Even cutting variable out you'll see wild fluctuations day to day. But the weekly and monthly trend smooths out and doesn't lie.

Check out my plot. 10 weeks on 1mg. The plateau last 12 days had me concerned, esp the day that peak popped up, but I determined to give it two weeks to resolve. I hit a new low last two days in a row and am moving again. My pause was old Reta and 3rd week of heavy full body workout, but the fat loss has caught up with the extra water in my muscles from DOMS and should continue general down trend going forward. If I hit a minimum 2 weeks at a stall, I'll go up...or cut calories. People forget that as you lose weight your BMR calorie needs drop too - you have to watch for true plateaus and adjust scientifically - and not always just titrate up. I hope this helps and illuminates things. Good luck and above all - just stay at it!

attachments-1779455710177-webp.24228.webp
 

Attachments

  • attachments-1779455710177-webp.24228.webp
    attachments-1779455710177-webp.24228.webp
    33.9 KB · Views: 2
Thanks guys, for sharing experience of yours. These all give me some picture of an issue. Tomorrow will weight in on the gym's scale which is showing bf, muscles, fat mass etc, and will see what actually happened thorough the week. Monday is Reta shot day, so have a couple days to make a decision whether to titrate or not and if I do how much then.
 
ultima thule said:
Thanks guys, for sharing experience of yours. These all give me some picture of an issue. Tomorrow will weight in on the gym's scale which is showing bf, muscles, fat mass etc, and will see what actually happened thorough the week. Monday is Reta shot day, so have a couple days to make a decision whether to titrate or not and if I do how much then.
Don’t dig too hard into the numbers on the scale. My scale has BF, muscle mass, skeletal muscle, protein, water and etc and etc.

They change every time my weight changes.

Zoom out, look at all data over the full timeline.
 
ultima thule said:
Thanks guys, for sharing experience of yours. These all give me some picture of an issue. Tomorrow will weight in on the gym's scale which is showing bf, muscles, fat mass etc, and will see what actually happened thorough the week. Monday is Reta shot day, so have a couple days to make a decision whether to titrate or not and if I do how much then.
Finally, welcome to Team Daily Trackers. Once you're with us, you're in for life. Alright, so we identified your enemy. He's DOMS. We've the weapons customized to deal with DOMS. Fluid weight from lactic acid driven inflammation is our common enemy. We'll show them no mercy. Stay the course, don't titrate unnecessarily. And when in doubt, go with the lowest dose.

P.S: Remember, what's best in life? Crush your plateaus, see them driven before you, and hear the lamentation of their adipose.
 
Cannonball72 said:
Don’t dig too hard into the numbers on the scale. My scale has BF, muscle mass, skeletal muscle, protein, water and etc and etc.

They change every time my weight changes.

Zoom out, look at all data over the full timeline.
This is precisely why I prefer to weigh weekly rather than daily. If my weight fluctuates up, I get way too in my head and wind up feeling bad about myself. Weekly weigh-ins reduce my anxiety, but to each their own.
 
lessthanhalf said:
What you are experiencing is perfectly normal day to day and week to week variations in fluid balance. It can be plus or minus a kilo or 2 . If there is no significant change in calorie intake or exercise, then there is no reason to believe that energy balance will have changed, so the rate of change of fat or non fat mass should not change, which just leaves variation in fluid balance. And the timing fits well too, when you first start losing weight you lose extra fluid as your body depletes glycogen stores and eventually it tends to even back out a bit.

If you track weight for long enough you will get periods where it looks like weight loss has stalled, or goes up a bit, my scales showed no changes for 6 weeks at one point, but averaged out over time the rate of weight loss had not really changed. At 6 weeks it is too early for changes in energy expenditure from lowered mass or low calorie adaptation to be significant factors.
Im going with fluid balances and hydration as well...if i urinate 9 times in a day and shit twice im lighter than a day i piss 4 times and shit once. By almost 3lbs.
 
I totally get the desire to track everything when first starting this cool new drug. But the beauty of Reta for some of us is that it just plain works whether we track calories, macros, exercise, etc. or not. I always hated that part of dieting and absolutely love that the scale usually drops a little every week with no effort on my part. And if it goes up a bit for a few weeks, I don't worry and stick to the titration plan. I do keep track of weight once a week but don't bother with the other metrics. They'll work themselves out.

However, I do expect to increase the dose early if I notice a distinct increase in appetite or portion size and conversely will delay escalation if I feel like it's still working the same. Unlike many of the other Peptides we experiment with, the GLP-1 agonists have very rapid and noticeable effects. I can't imagine not knowing whether you got the placebo in any of these trials.
 
Bioexplorer said:
I totally get the desire to track everything when first starting this cool new drug. But the beauty of Reta for some of us is that it just plain works whether we track calories, macros, exercise, etc. or not. I always hated that part of dieting and absolutely love that the scale usually drops a little every week with no effort on my part. And if it goes up a bit for a few weeks, I don't worry and stick to the titration plan. I do keep track of weight once a week but don't bother with the other metrics. They'll work themselves out.

However, I do expect to increase the dose early if I notice a distinct increase in appetite or portion size and conversely will delay escalation if I feel like it's still working the same. Unlike many of the other Peptides we experiment with, the GLP-1 agonists have very rapid and noticeable effects. I can't imagine not knowing whether you got the placebo in any of these trials.
Yeah gotcha, but as I'm newbie in Reta and peptides in general, I have some experience in losing weight basically. 4 years ago I had to quit gymming due to the shoulder injury and gained a lot of lard. When reached the critical mass, which made me struggling to close the laces, decided to do something with that. Started keto, which converted to low carb afterwards, and having calorie deficit. After 16 months I lost 42kg/92.5lbs in total...but then I started a new job, where I have no activity at all. In a previous job I was doing 20k steps average, now around 4-5k. Hence hit the gym again in January (shoulder is much better/Glow helps too) Despite of keeping the diet I gained again around 15 kg which I'd love to lose, that's why on Reta now. Anyway I know losing weight takes time, and the slower it goes the better/healthier it is. But when on keto, I was losing weight step by step, and don't remember the situation I've gained some weight in the meantime. So that's why I opened that discussion, cuz today's result concerned me a bit. And also reading lately about the magical feature of the 4mg Reta and that glucagon hits right there...so I'm supposed to titrate soon anyway, but hesitating if it is the moment to jump on 4mg, stay for another week or two on 2mg, or get through 3mg at first...
 
Gotcha Ultima. And that's a lot of weight you lost pre GLP-1s. Well done. Hopefully it'll be easier this time with Reta.

I still have a couple weeks at 2mg then planning on 3mg for 4 weeks. I'm not buying the magic 4mg minimum for glucagon agonist theory and I'll probably get there eventually anyway.

Good to know Glow is working for your shoulder. I tried BPC-157 for a couple months with no improvement in shoulder pain but I've been considering trying Glow or Klow.
 
Bioexplorer said:
Gotcha Ultima. And that's a lot of weight you lost pre GLP-1s. Well done. Hopefully it'll be easier this time with Reta.

I still have a couple weeks at 2mg then planning on 3mg for 4 weeks. I'm not buying the magic 4mg minimum for glucagon agonist theory and I'll probably get there eventually anyway.

Good to know Glow is working for your shoulder. I tried BPC-157 for a couple months with no improvement in shoulder pain but I've been considering trying Glow or Klow.
From my perspective I would recommend to go for Klow eventually. It is actually Glow plus Kpv. As I am really happy of Glow and the improvement it gives me so far I regret didn't get Klow. Found out it could be very helpful with my skin issues, so gonna order Kpv by itself and just add to the stack. Unnecessary hassle if I would get the Klow at first...
 
I remember back in the day when they would take out calipers to measure one's gut fat and body mass percentages in college health/gym classes. Don't know if that's still around. I just used the time-worn and very scientific method of grabbing my gut and giving it a little shake, then grabbing my shoulder to see if all I can still feel is bone after all of the muscle wasting I didn't account for.
 
ultima thule said:
It is my 6th week on Reta now, and it was so far so good....but as every Friday morning I checked my weight today and boom! Surprise! So I started from 1mg per week. On the 3rd week tirtrated to 2 mg. Results were just perfect, cuz my weight was dropping 1.5kg/3.3lbs per week average. But today, when I stepped on weight scale it shows 0.5kg/1.1lbs more, than the week before. 🫤 So I tried to figure out, if anything changed in my routine the last week. First thing is Epithalon, I started a week ago (0.5mg/day), and the second, I add a bit more protein to my daily intake (around 30g). Don't think that any of those had any impact on gaining within last week. All of the rest is, as it was beforehand. 5 days a week at the gym, high protein/low carb/low fat diet, 2 meals per day, sleeping well, around 7h...I'm a bit confused, cuz Reta shot day is Monday and wanted to titrate to 3mg this time, but reading now alot about the magic threshold of the 4mg of Reta, and considering to jump on that dose now. And btw, food noise, feeling full while eating, no cravings, those all are working fine. Also have no side efects at all on 2mg. So at first, wondering, why I gained in the 6th week on Reta, and what dose would you recommend for me to jump on now. Or maybe stay on 2mg and see what will happen?
I had a similar experience. I dropped for 2 weeks straight on 2mg, then gained. Then went to 3mg for 4 weeks and lost a little but kind of stalled after week 2, I was just going up and down in weight. Once I went up to 4 I started dropping again. I know people just say to go straight to 4 but honestly I’m really glad I did 3 first. I definitely felt it working even though I stalled, I just don’t always eat the best. It’s not a race, take it slow.

I’m getting side affects at 4, nothing unmanageable but heart burn if I eat anything at 9pm or any greasy food at all. It’s actually hard to eat lunch but still get hungry at dinner. I’m glad I went from 3 to 4 though, I think if I went straight from 2 to 4 my side effects could have been worse.
 
Imfrijole said:
I had a similar experience. I dropped for 2 weeks straight on 2mg, then gained. Then went to 3mg for 4 weeks and lost a little but kind of stalled after week 2, I was just going up and down in weight. Once I went up to 4 I started dropping again. I know people just say to go straight to 4 but honestly I’m really glad I did 3 first. I definitely felt it working even though I stalled, I just don’t always eat the best. It’s not a race, take it slow.

I’m getting side affects at 4, nothing unmanageable but heart burn if I eat anything at 9pm or any greasy food at all. It’s actually hard to eat lunch but still get hungry at dinner. I’m glad I went from 3 to 4 though, I think if I went straight from 2 to 4 my side effects could have been worse.
I had a huge problem with heart burn since my childhood, but it's completely gone since I started low carb diet.
 
Sir Chuck said:
I remember back in the day when they would take out calipers to measure one's gut fat and body mass percentages in college health/gym classes. Don't know if that's still around. I just used the time-worn and very scientific method of grabbing my gut and giving it a little shake, then grabbing my shoulder to see if all I can still feel is bone after all of the muscle wasting I didn't account for.
Certainly still happens I had a girl at work this week saying her PT got the old calipers out in her check up. Crazy considering how accessible the biometric machines are now
 
Well guys, I stepped on the gym scale and here's another surprise. On the left hand side my results taken last Sunday, and on the right today's score. In general it looks like I lost a bit of fat, and gained a bit of muscles and it has taken only 6 days! My yesterday's weighting (which initiated that thread) was at the morning, before I visited the crapper, so it might be like a few of you said, water, and other stuff in the system made my total weight a bit higher. Basically thorough those 6 days, I lost 0.9kg eventually...I checked my weight on the home scale, when back home and it showed 0.4kg more than the gym scale, which means it is not so precise...anyway it's another proof how awesome thing Reta is. Of course I helped it with a strict diet, hard workouts and sleeping 7h per night average...but still this compound let you lose fat and gain muscles simultaneously! And btw. Don't mind too much my high which is a bit different on the scale tickets , just probably stood in a bit different position while taking a weight. Anyway I'm 177cm, as far as I remember 😁
 
Status
Not open for further replies.

Members online

No members online now.

Forum statistics

Threads
4,434
Messages
86,405
Members
7,877
Latest member
jhonpdr
Back
Top