Can you cite to the portion of the SURPASS study testing of 30mg doses was actually happening instead of the Google AI results you got from a leading inquiry?Airborne Daddy said:
I don’t think you’ll find it.
25-60mg Tirz dosage weekly
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I don’t think you’ll find it.
They have not.Airborne Daddy said:
I went down this rabbit hole yesterday with AI. They would not state that higher doses were being tested because it wasn't published yet. After pressing the issue and asking in a multitude of different ways, AI finally stated that higher doses, although not published, were being studied. In an abundance of caution, AI doesn't always state everything they have access to.
AI says higher doses are 10-15mg, not doses beyond the FDA approved doses.byefatlicia said:
Studies are reported on even in early stages.
Can’t find a single mention of 30mg studies, even early studies, and certainly not back in 2023.
I never said 30mg doses. I said higher than the FDA approved 15mg dose. Maybe that's why?
Can you cite to what you found? The actual study?byefatlicia said:
That screenshot isn’t a study — it’s an AI Overview, not a peer-reviewed paper. And it doesn’t say tirzepatide is dosed at 30 mg in humans. It’s summarizing SURPASS data (which used up to 15 mg) and then speculating about kidney effects.Airborne Daddy said:
AI Overviews pull info from across the internet and often mash details together. It ’s mixing up “UACR ≥30 mg/g” (a kidney-damage threshold) with a 30 mg drug dose. SURPASS showed benefits on albuminuria in people with baseline UACR ≥30 mg/g, but the trials only tested up to 15 mg weekly (and single-dose SAD studies in humans went as high as ~8 mg). That’s not evidence for 25–60 mg/week or dosing every 3–4 days.
So, pretty sure the only thing that hit 30 mg in that screenshot was albuminuria, not tirzepatide. Google AI mixed up a kidney marker with a drug dose — which is why using AI summaries as a ‘credible study source’ is shaky from the start..... Just a quick reminder
YoYoFat said:
Here ya go. Ai must have seen this and confused it with dosage. You win. Thought about ending my existence but ultimately decided you can still bl#w me. Now pin your 2.5mg and prep ur chamomile tea.... However, when reta is approved watch how quick the tirz is studied at 30 and 45mg.Jfrick11 said:That screenshot isn’t a study — it’s an AI Overview, not a peer-reviewed paper. And it doesn’t say tirzepatide is dosed at 30 mg in humans. It’s summarizing SURPASS data (which used up to 15 mg) and then speculating about kidney effects.
AI Overviews pull info from across the internet and often mash details together. It ’s mixing up “UACR ≥30 mg/g” (a kidney-damage threshold) with a 30 mg drug dose. SURPASS showed benefits on albuminuria in people with baseline UACR ≥30 mg/g, but the trials only tested up to 15 mg weekly (and single-dose SAD studies in humans went as high as ~8 mg). That’s not evidence for 25–60 mg/week or dosing every 3–4 days.
So, pretty sure the only thing that hit 30 mg in that screenshot was albuminuria, not tirzepatide. Google AI mixed up a kidney marker with a drug dose — which is why using AI summaries as a ‘credible study source’ is shaky from the start..... Just a quick reminder
Airborne Daddy said:
So… screenshots from Google AI = ‘they’re studying 30 mg tirzepatide, so 60mg 2x a week is fine’?Airborne Daddy said:
And an experimental sema dose = green light for DIY megadosing?
That’s not research — it’s just irresponsibility with citations .
You do you, truly… just maybe ease up on the misinformation for the rest of us, especially if it could be dangerous.
That's UACR. It stands for urine albumin-to-creatinine ratio. It's a test that measures the amount of albumin and creatinine in a urine sample to help detect early kidney damage. It's measures in mg. They measured UACR at baseline and the study participants needed to have a UACR ≥ 30 mg/g (a threshold often used clinically to indicate micro- or higher albuminuria, a sign of kidney stress/damage) and/or people with reduced baseline eGFR. and again at the end of treatment (week 40 or 42, depending on the subtrial).
They looked at Tirz at 5mg, 10mg and 15 mg and by measuring before and after...... They could estimate how much of the UACR reduction might be due to changes in glycemic control (HbA1c) and weight loss — and how much might be “direct” effects (or due to other factors) associated with tirzepatide.
They looked at Tirz at 5mg, 10mg and 15 mg and by measuring before and after...... They could estimate how much of the UACR reduction might be due to changes in glycemic control (HbA1c) and weight loss — and how much might be “direct” effects (or due to other factors) associated with tirzepatide.
No need to pick on her, you're after me. Your shocked anyone could ever do more than 2.5mg the last 18months like you. Here, I'll admit, looks like ai misread 30mg and associated it with dosage. Rest assured as soon as reta is approved the unpublished research with 30 or 45mg or tirz will surface. Just like the triple max doses of sema so they're not left behind.YoYoFat said:
So you didnt read my response where i conceded. It wasnt posted as proof of my claim. I didn't ask what it meant. I admitted ai seen 30mg and tirz study and decided that was the dosage. Your Google skills are also impressive.Jfrick11 said:
So they haven't studied sema up to 7 or is it 7.5mg? Who da fuck said 60mg a week of tirz? Your gonna put words in my mouth....Jfrick11 said:
There’s a huge difference between discussing data and whatever this meltdown is.Airborne Daddy said:
If AI mixed up UACR with dosing, great — we cleared that up.
But the threats, sexual comments, and weird tough-guy energy don’t make your point stronger.
When real dosing data exists, I’ll read it like everyone else.
Until then, let’s keep it to facts instead of fantasies and insults.
Threats? Weird tough guy energy you can feel over the internet? U got me for sayin b#ow me, it's a figure of speech not sexual harassment. I'm sure you reported me to Zipp, so good job buddy. Ur not gonna combine my comments with the op and imply I recommend two 30mg tirz doses a week...Jfrick11 said:
Literally the post you’re defending is titled 25–60 mg tirz weekly. You tried to back it with research that doesn’t exist, were shown the correction, and your immediate pivot was a sexual threat. That’s not confidence — that’s pathetic collapse. And nice edit taking out telling me what I can put in my mouth. Now that's brave.Airborne Daddy said:
At this point, it’s clear you’re not intellectually equipped for a factual discussion, so there’s really nothing left here to engage with. And I mean nothing.
I will let that slide because you seem new here but i have over a year of dosing outside of regular limits. Maybe you should look at past post before making a comment about someone's research on the matter at handTed R said:Stupid and irresponsible to post something like this, even if you REALLY are doing it. "Here, hold my beer and watch this...."
just shot another 25mg with a little 1mg of sema to wash it downambot88 said:
Whos defending the post? I incorrectly suggested they're looking at tirz over the max dose so 30mg isn't crazy. I correctly stated they're studying sema at triple the max dose and then you are non stop breaking down every nomenclature and scientific study. Even after you got a "my bad" from me.... and you will likely go to midnight. I have a pretty Italian wife to spend my evening with and hope you have a great week. Lol, a sexual threat.... Spend less time filing complaints at human resources bruh.Jfrick11 said:
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