Which did you feel less tired on and had more energy - Reta or Tirz?

[hoobz]

Question for folks who've been on both.

I'm currently on Tirz, just my 4th week and all's great apart from feeling my energy levels dropped considerably, weight lifting at the gym feels more tiring, cardio is hard too.

I'm having a 7-day mountain climbing course planned end of July and I feel if I'm gonna be on tirz, it's gonna be reeeaaaly difficult for me. The course is physically demanding and it's a full blast on 6 out of 7 days.

So I'm considering switching to Reta if this means more energy and less general tiredness.

Anyone been on both peptides and can compare? I know dosage matters too, but maybe you felt somewhat noticeably less tired on one of them?

Another idea I have is to titrate down (but hell, I'm just on 2.5 starting dose lol) like 2 weeks before the course or stop taking tirz for that period.

Need some thoughts and experience, maybe someone was in a similar situation. Thanks!

 

[MFGamesta]

I was so tired on tirzapatide. Got much better on retatrutide. Could be I was eating better.

 

[Lyophilized]

So I'm considering switching to Reta if this means more energy and less general tiredness.

That's what happened with me

But I wouldn't say I felt "more energy"... I would say "less tired"...

 

[hoobz]

I was so tired on tirzapatide. Got much better on retatrutide. Could be I was eating better.

seems like appetite suppression is not as hard, that's what I'm hearing, tbh I have problems getting more than 1.2g of protein/kg of body mass on tirz, I was hoping to be able to up it to around 1.6...

 

[PEP-Guardyola]

I will share my brief experience with Reta and Tirze.

With Tirze, I experienced noticeable appetite suppression upon first use, which gradually decreased over the weeks, requiring me to adjust the weekly dose.

I didn't get along well with Tirze; I felt my energy levels were low because I couldn't even eat what was planned in the diet. I believe it's very effective in cases of severe food cravings and for people who have great difficulty adhering to a diet or clean eating plan. Most of the time, the day after application, depending on the dose, I felt nauseous and had little desire to eat.

With Reta, even starting with only 1mg (5 weeks ago), I felt that my psychological control over eating strengthened, and I didn't experience appetite suppression that prevented me from eating what I needed. Energy levels were always stable or optimized, without any nausea or some "food aversion", and I felt, perhaps a placebo effect due to the expectation I had created, a more pronounced lipolysis.

I've been on only 1mg of Reta weekly for 5 weeks. I feel great, and now I feel the effects are starting to diminish, and I'm experiencing some cravings "out of the blue" that I didn't feel in the first 4 weeks.

I'll continue my tests with Reta, always aiming for the lowest possible dosage and only increasing it when I feel an extreme need. I've heard that Reta at higher dosages (+6mg) has more pronounced lipolytic effects due to the action of Glucagon; I don't know how true that is, but I will definitely test it.

In the future, when I reach a few weeks with 6mg per week, I will reduce the Reta dose by at least 50%-70% and add 1mg-1.5mg of Tirze (to controll the "food noise") along with the Reta for the maintenance phase.

 

[mrmors]

I've not experienced any effect on either one so I'm thinking it might be purely down the calorie restriction maybe?

For information I ran Tirz 2.5>7.5mg over 6months

The last few weeks I've ran a combo of 5mg of Tirz+2mg of Reta, and now 2.5mg Tirz and 4mg of Reta.

I train 7days a week and haven't noticed a drop in energy/tiredness

 

[5byfive]

I had a lot of fatigue the first week or two but it got better after that. I think part of that was that I was burning more calories. I was shooting for maintenance but started dropping. The numbers showed that it kicked up my daily calorie burn by about 15%. I know it doesn't do that for everyone but it definitely did for me. So I think there may have been some fatigue from the med but also from the increased energy expenditure.

I also found out I could no longer work out fasted. I have always done that. Reasearch says that's absolutely fine and I always felt better that way. Now I'm hungry in the morning and my energy sucks if I try and lift fasted. More calories before working out may be something to consider.

Before making a change, I would suggest take a look at what kind of a deficit you are in and make sure its not too high. If that solves it, great, if not you have more information to help you transition to reta.

 

[slick1]

Question for folks who've been on both.

I'm currently on Tirz, just my 4th week and all's great apart from feeling my energy levels dropped considerably, weight lifting at the gym feels more tiring, cardio is hard too.

I'm having a 7-day mountain climbing course planned end of July and I feel if I'm gonna be on tirz, it's gonna be reeeaaaly difficult for me. The course is physically demanding and it's a full blast on 6 out of 7 days.

So I'm considering switching to Reta if this means more energy and less general tiredness.

Anyone been on both peptides and can compare? I know dosage matters too, but maybe you felt somewhat noticeably less tired on one of them?

Another idea I have is to titrate down (but hell, I'm just on 2.5 starting dose lol) like 2 weeks before the course or stop taking tirz for that period.

Need some thoughts and experience, maybe someone was in a similar situation. Thanks!

I have not used tirz but reta knocks my energy levels down hard at anything above 4mg for the first 2-3 days after shot, then the fatigue tapers off. It doesn't feel like anything to do with food intake, it just taxes my body and makes me feel worn out but by day 5-6, start feeling back to normal, then it's time to dose again but it's working good for weight loss.

 

[BH_LOVER]

With Reta, even starting with only 1mg (5 weeks ago), I felt that my psychological control over eating strengthened, and I didn't experience appetite suppression that prevented me from eating what I needed.

I have found the longer I have been on Tirz, this has been my experience. In the beginning, I wasn't eating but one meal a day and that was forced and I was full after a couple of bites. Now at a year+ on Tirz, I am seeking food, eating lunch and still maintaining my weight loss with a minimal dose. It all comes down to different people react differently.

 

[hoobz]

thank you folks! some nice insight for me to consider.

@PEP-Guardyola - good to hear you're upping very slowly and titrating up only if absolutely needed. I've been reading up on and listening to a lot about these peptides and what most experts say, lots of people are going up too fast, and consequently losing too much weight.

I don't have a lot to lose just probably around 10 kgs to the 4 I have lost so far, so going slow is the way to go, I believe. It's interesting to hear you're psychological control of hunger is stronger now on Reta, this is what I want even after reaching my goal body weight and body look. It's helps me so much not only with food cravings, so I consider being on and off of it for life maybe.

@BH_LOVER - glad to hear it! what's your maintenance dose?

@mrmors - thanks for sharing! how are these two combos working for you, feel any different? - "The last few weeks I've ran a combo of 5mg of Tirz+2mg of Reta, and now 2.5mg Tirz and 4mg of Reta."

 

[mrmors]

@hoobz To be honest I've felt no different at all during the attempted switch. No change in appetite or energy etc. I was hard locked on 100kg for some reason regardless of training 7x times a week, and being in what I thought was a deficit, on Tirz, hence me bringing in Reta. I don't weigh myself that often, maybe once a week or every few weeks or something, so it'll be interesting to see if Reta has changed anything on that front.

On a side note, it looks like I stumbled on some sort of underlying Liver issue that my GP hadn't spotted, I had high Billirubin levels for a prolonged period, which my GP was meant to be on the lookout for, and hadn't bothered about it. I started taking Reta, and my Bilirubin level s have plunged 25% towards the safety zone! I'd heard how Reta was get for clearing out fatty Liver etc, but it looks like it might be doing my liver wonders in a short period of time! Due another blood test in 2months, and I'll have been on Reta 2.5months then, not 2wks, so it'll be interesting to see any change.