Tirz not working anymore

[Smiter]

and that's the bottom line.

That was some stone cold truth.

As of today, I've lost 115#s or 34% of my starting body weight. Clearly I've blown far past what the clinical trials said I would lose.

This is the way.

Now I am slowly noticing that it isn't working anymore somehow; I do feel less hungry, but the food cravings are back and I can eat a lot again

Off the top of my head, 3mg seems too low a dose. I would get it up to 5mg, slowly titrating up or shotgunning a lower dose of Reta. It depends on how much you have yet to lose.

 

[Calm Logic]

I was on 5 mg of tirz for my second week (instead of second month). That was on a prescribed, aggressive titration schedule (by a quack maybe, but a local, board-certified internist with many patients on GLPs).

The importance of rate as a factor is individualized.

Yeah, some people are super responders (like 1-mg reta users who lose weight for months on that dose), and some people need 20 mg of tirz just to maintain. Most of us are somewhere in between. And then there are the true non-responders who haven't really lost any weight at any dose.

 

[TazaTaza]

Don't titrate up. I had a procedure where I had to stop taking it for 6 weeks bc of anesthesia. When I took it again (under doc supervision) it felt like a freight train hit me.

Try taking a break first and then starting back up at starter level.

My experience is different I lost 10 lbs/month consistently on 2.5/5/7. I ironically stalled at 10, and my doc made me stretch out my days to 10-14 which helped w/losing more which was odd. I'm currently grey back down at 7.5 losing still.

 

[ColdSmoke]

Hello dear peppers,

I have been using Tirzepatide for a while now and have been adding Cagritilinde for about six months. I take 3mg Tirzepatide and 0.5mg Cagritilinde weekly. Now I am slowly noticing that it isn't working anymore somehow; I do feel less hungry, but the food cravings are back and I can eat a lot again. What is the best thing for me to do?

Dose up to 5mg Tirz and then to 7.5 if your still not getting results. You wont need Cag at all on higher doses of Tirz

 

[Clyde22]

Hello dear peppers,

I have been using Tirzepatide for a while now and have been adding Cagritilinde for about six months. I take 3mg Tirzepatide and 0.5mg Cagritilinde weekly. Now I am slowly noticing that it isn't working anymore somehow; I do feel less hungry, but the food cravings are back and I can eat a lot again. What is the best thing for me to do?

Are you having overall increased hunger or is it more towards right before your next dose/shot?

 

[Blueeyedme]

Hello dear peppers,

I have been using Tirzepatide for a while now and have been adding Cagritilinde for about six months. I take 3mg Tirzepatide and 0.5mg Cagritilinde weekly. Now I am slowly noticing that it isn't working anymore somehow; I do feel less hungry, but the food cravings are back and I can eat a lot again. What is the best thing for me to do?

I’ve always followed this titration flow chart to keep me at the minimum effective dose of tirz.

 

[x3737]

saying it doesn't work when your on 3mg dose is not correct. you still have runway for 5x that dose receptors get's used to the dose and that's why we can titrate up

 

[Sasquatch]

Don't titrate up. I had a procedure where I had to stop taking it for 6 weeks bc of anesthesia. When I took it again (under doc supervision) it felt like a freight train hit me.

Try taking a break first and then starting back up at starter level.

My experience is different I lost 10 lbs/month consistently on 2.5/5/7. I ironically stalled at 10, and my doc made me stretch out my days to 10-14 which helped w/losing more which was odd. I'm currently grey back down at 7.5 losing still.

I'm curious as to what your starting and goal weights are/were?