As I wrote before: Over a year ago, started Tirz, slowly up to 10mg/week. After 6 months of low energy, added Cagri, low doses, as Tirz effect was slowing down to 0.5# a week. Cagri made me nauseous but had 0 food noise. No energy boost. 3 months later, added Reta low dose (0.5, 1.0, 1.5mg) to test RHR. No issues but energy level increasing (maybe because I was loosing weight).
A year after I started the 'research', I stopped Cagri (6 months on Cagri), I increased Tirz to 15mg@6 days, and increased Reta to 2mg+ slowly. 57 weeks, down 75 lbs (Average 1.3 lbs/week). 0 exercise. No appetite on Reta, is as good as Cagri, but without being nauseous. In a few months, I will be titrating down Tirz as I clear up that stash, while slowly increasing Reta to get rid of 25 more lbs. At Reta 3mg, rhr is now ~10 beat faster and energy level is back.
After 26 weeks, most research candidates reported diminishing results, thus the reason I stacked this way. This may not work at all for you. Cagri act on a different receptor. I feel is a good complement to Sema, Tirz or Reta.
Suggestion : Sema (is cheap). Once the weight loss diminishes, Add Cagri, or switch to Tirz, and later add Cagri. I kept Reta for the final part of my journey. You have to be patient. I find that the longer you take to reach a max dosage, the longer your period of loosing weight is, as your body adapts to the higher dosage. And this is from an old guy, sitting 12+ hours a day behind a computer and doing no exercise.
