Reta cancer data drops

[desinr-gal]

Thanks for sharing!

 

[wonttellyou]

Reta! Fuck yeah!

 

[CNCCurrency]

I believe people stating that these results are just a subproduct of weight loss are cutting it too short. It's not the first time I read about similar results on top of what would be expected with regular weight loss.

I also remember listening to a podcast by Dr Attia saying we don't actually know if obesity itself causes cancer, and he doesn't believe so. But things like insulin resistance could be the culprit

As stated above, Being obese IS a health risk for many reasons, including that higher amounts of body fat are associated with an increased risk of a number of cancers.

 

[Pin&Play]

As stated above, Being obese IS a health risk for many reasons, including that higher amounts of body fat are associated with an increased risk of a number of cancers.

Let's not forget obesity is determined by BMI alone, which is a silly number.

Sure, higher amounts of body fat are associated with increased cancer risks, but this does not confirm that the excess of adipose tissue causes cancer. This is a typical example of correlation =/= causality

Is it the fat or the diet? Or the blood sugar? Or the insulin resistance? Inflammation? Or some other factor we don't even know about?

Then absolutely, getting lean will almost always provide some kind of protection.

But there are people with a healthy BMI and metabolic issue that would like to know the answer

 

[Chocolate Boy Wonder]

Ok I'm posting the twitter link bc the wsj article is pay walled and it summarizes it.

Eli Lilly released retatrutide Phase 3 data yesterday. 28% weight loss in 80 weeks. The most powerful obesity drug that’s ever been tested.

And today the cancer signal drops.

12,112 patients. Seven tumor types. GLP-1 users had half the lung cancer metastasis rate (10% vs 22%).… https://t.co/wqMGXWckw0
— Avi Roy (@agingroy) May 22, 2026

View: https://x.com/agingroy/status/2057717218608099484?s=46&t=zVDa3_JfTajSPzmg_nqxMg

12,112 patients. Seven tumor types. GLP-1 users had half the lung cancer metastasis rate (10% vs 22%). Breast cancer: 43% cut. Colon cancer five-year mortality in a separate study: 15.5% vs 37.1%.

these effects are clearly beyond just weight loss, GLP agonists are showing more and more effects it's exciting stuff.

Click to expand...

No cause & effect, and could be part of the P.R machine, but I hope it is true because this is great news!

 

[TooGood76]

No cause & effect, and could be part of the P.R machine, but I hope it is true because this is great news!

these are post hoc observations of course they don't show a definitive casual link it's far too early for that.

 

[medavaca]

Hopefully these kinds of findings will eventually get to the bottom of what's really causing all these things (already-identified metabolic syndrome aspects; joint pain; mental health imbalance; cancer) which are mitigated by GLP-1 endruns. But clearly not root-caused by natural GLP-1 bioavailability problems, I believe.

I would love to see the fasted insulin levels of the groups for comparison. The metabolic dysfunction is so overlooked by current mainstream healthcare.

 

[medavaca]

I believe people stating that these results are just a subproduct of weight loss are cutting it too short. It's not the first time I read about similar results on top of what would be expected with regular weight loss.

I also remember listening to a podcast by Dr Attia saying we don't actually know if obesity itself causes cancer, and he doesn't believe so. But things like insulin resistance could be the culprit

I love listing to Ben Bikman (The Metabolic Classroom). His specialty is cell biology, with a personal interest in fat cells. He is a professor at BYU and runs research there. He really hammers on hyperinsulinemia (high blood insulin levels). Insulin is one of the body's primary anabolic hormones and promotes cellular growth, including many types of cancer cells.

 

[Spork]

I wish I could tolerate Reta. It gives me gall bladder pain that travels to back and shoulder pain. Guess I am a TirzGirl for the duration.

If you get that feeling again, you should really consider getting it checked out by a medical professional. If it's pancreatitis. that shit can go south real quick, tissue can go necrotic etc.

Not trying to be alarmist, it could have just been a run-of-the-mill gallbladder attack, to be sure, but if it's not...

 

[QueenMuntha]

If you get that feeling again, you should really consider getting it checked out by a medical professional. If it's pancreatitis. that shit can go south real quick, tissue can go necrotic etc.

Not trying to be alarmist, it could have just been a run-of-the-mill gallbladder attack, to be sure, but if it's not...

Will do. I can trigger it if I start Reta again. LOL.

The referential back pain went away 10 days after stopping 8mg weekly Reta.

 

[lazygardener]

Ok I'm posting the twitter link bc the wsj article is pay walled and it summarizes it.

Eli Lilly released retatrutide Phase 3 data yesterday. 28% weight loss in 80 weeks. The most powerful obesity drug that’s ever been tested.

And today the cancer signal drops.

12,112 patients. Seven tumor types. GLP-1 users had half the lung cancer metastasis rate (10% vs 22%).… https://t.co/wqMGXWckw0
— Avi Roy (@agingroy) May 22, 2026

View: https://x.com/agingroy/status/2057717218608099484?s=46&t=zVDa3_JfTajSPzmg_nqxMg

12,112 patients. Seven tumor types. GLP-1 users had half the lung cancer metastasis rate (10% vs 22%). Breast cancer: 43% cut. Colon cancer five-year mortality in a separate study: 15.5% vs 37.1%.

these effects are clearly beyond just weight loss, GLP agonists are showing more and more effects it's exciting stuff.

Click to expand...

The GLP cancer paper has nothing to do with Reta. This study only includes currently on market GLP-agonists. This is not "Reta cancer data" since that data does not exist for a drug still in weight loss trials (Will Reta do the same? Probably, but there's no data yet).

 

[jmon1977]

I work in oncology and we did data analysis of over 400k cancer patients (of the GLP-1 users, 74% were prescribed GLP-1 after cancer diagnosis).

The correlations are pretty good. After 24 months, the OS (overall survival) rates for Breast and Prostate - 97.9% on GLP, 92.6% not on GLP.