Crowreap said:
400mg is the common daily limit in several countries including the US. The ratio I use is 5mg/kg.
Canada says 2.5mg/kg for children.
Reta and Caffeine
- Thread starter Bigdog0628
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400mg is the common daily limit in several countries including the US. The ratio I use is 5mg/kg.
Canada says 2.5mg/kg for children.
7 months mounjaro at 5mg and 7-8 cups coffee/day. Didn't feel anything like that. 1 month on reta at 3mg and also nothing different except much more thirst than before and less hunger suppression in comparison with tirz.
I’ve actually noticed something similar. I’ve always had a pretty high caffeine intake, but since starting reta, stimulants definitely seem to hit differently for me. It feels like I became more sensitive to the overstimulated/anxious side of caffeine.
Personally though, I kind of like it because it’s made me cut way back overall. I’ve been substituting some of the caffeine with 200mg modafinil instead, which feels smoother and less jittery for me.
Makes me wonder if some of the GLP-1 effects on dopamine/reward signaling are changing how stimulants feel.
Personally though, I kind of like it because it’s made me cut way back overall. I’ve been substituting some of the caffeine with 200mg modafinil instead, which feels smoother and less jittery for me.
Makes me wonder if some of the GLP-1 effects on dopamine/reward signaling are changing how stimulants feel.
Oh damn, I had no clue it was that high. I only consume 200 mg daily before the gym. So when I hear something like 400, I'm thinking that might be a bit much. And the 200 mg for me gets me on crack for the next few hours!!woundcarping said:
So I cut my caffeine I take back to 200mg this morning and 100 this afternoon and it seems to be the sweet spot. Man I love Reta it has cut out so many bad habits in my life and just don’t have the desire for them like I’ve had for decades.
A lot of people consume well over 400mg of caffeine per day.
At this point there is actually fairly decent evidence it is good for you , at least at reasonable doses, reducing risks of dementia and diabetes and others. Very high intakes of caffeine above 1g/day are probably a bad idea.
The problem people have with caffeine is if you tend to get anxiety, it can make it worse and it can stimulate the sympathetic nervous system causing physical effects that feel like anxiety and as a result cause anxiety via feedback. And any other drug that increases sympathetic nervous system activity can do the same or make caffeine effects more obvious, like reta. But it is not hard to reduce caffeine intake if getting adverse effects on reta, but maybe drop the dose back slowly to prevent caffeine withdrawl headaches or migraines.
At this point there is actually fairly decent evidence it is good for you , at least at reasonable doses, reducing risks of dementia and diabetes and others. Very high intakes of caffeine above 1g/day are probably a bad idea.
The problem people have with caffeine is if you tend to get anxiety, it can make it worse and it can stimulate the sympathetic nervous system causing physical effects that feel like anxiety and as a result cause anxiety via feedback. And any other drug that increases sympathetic nervous system activity can do the same or make caffeine effects more obvious, like reta. But it is not hard to reduce caffeine intake if getting adverse effects on reta, but maybe drop the dose back slowly to prevent caffeine withdrawl headaches or migraines.
I can’t tolerate the same amount of caffeine since starting Reta. I read somewhere to cut your caffeine in half do to increased heart rate but I honestly forget where I saw that!
Damn I wish I had this problem. Reta seems to give me less energy when weightlifting. Maybe I've adapted to it a bit over time, but I've had to get very disciplined about making sure I get carbs and preworkout before the gym. My theory is that the glucagon agonism just keeps my stored glucose so low that I have less available energy. I've had to keep my dose under 6mg/wk to feel normal. I've been taking reta for over a year and still can't get above that dose.Bigdog0628 said:
Have you tried adding Mots-C? I added that and it’s given me great energy!mybodyisasewer said:
You very definitely get into a low glycogen storage state when losing weight . It is using up this glycogen especially in the liver that causes a lot of the initial water weight loss on starting a diet as the glycogen needs water to keep it osmotically balanced.mybodyisasewer said:
So it is not necessarily just reta having this effect, weight loss itself keeps glycogen storage levels low.
I wonder if retatrutide affects adenosine receptors...
For me Mounjaro and strict eating like keto affects electrolytes. Caffeine, also being a diuretic, hits me harder and had to cut my intake or I would get headaches. Proper hydration is key. I also noticed this with another stimulant for adhd. I always now drink electrolytes and water in the morning before coffee.
I experience this with Tirz.Bigdog0628 said:
I drink yerba mate in the morning, first thing, before I have my breakfast. Been doing this for many years, Yerba contains mateine, which is the same compound as caffeine, just named differently.
I've been on Tirz for 8 weeks now, and for about 3-4 weeks I've been feeling anxious after my morning yerba, and I know that if that happens, I went too far with the dose.
I've cut it down by 1/3, but still have days when I feel it too much. I associate it with weight loss (stress on the body) and an extended period of reduced caloric intake.
Same. I have reduced my daily intake from 600 mg to just 2 cups of coffee and I haven't had the overstimulated feelings since. Also I wonder if just drinking coffee vs energy drinks have a different effect.hoobz said:
I don't use energy drinks anymore, but I would presume the same mechanism.Bigdog0628 said:Same. I have reduced my daily intake from 600 mg to just 2 cups of coffee and I haven't had the overstimulated feelings since. Also I wonder if just drinking coffee vs energy drinks have a different effect.
I introduced taurine yesterday (3g/day), which is supposed to calm the nervous system down and reduce anxiety, didn't feel anything like that today, but it's only the first day, we'll see.
I used to crush coffee and energy drinks and pre workout, but since starting reta i have not wanted or needed it at all. And if I do I a cup it hits me way harder, but the Cal deficit makes sense.
I don't feel jittery on my daily cup of coffee, but much like the others here, I consume far less caffeine than I used to. I was on at least 500mg caffeine a day in the form of coffee, tea, energy drinks, pepsi, and caffeine pills. Now I only drink one cup of coffee a day, which is quite a strong brew so I presume I'm getting around 200-250mg a day. The amount of money I save by not buying caffeinated drinks alone is probably in the hundreds per month.
Are you still dropping weight at the 6mg?mybodyisasewer said:
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