Oxytocin — Any Positive Experiences? (also Allopregnanolone and Clonidine)

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birdwhacker

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Title says it all. I've seen a few promising experiences on Reddit, one of them actually abbit worrisome, but the vast majority of people seem to get bad effects or nothing at all.

View: https://www.reddit.com/r/autism/comments/18ana26/ive_used_oxytocin_nasal_spray_for_almost_a_year/

View: https://www.reddit.com/r/AutisticAdults/comments/1prlu99/i_can_not_live_without_injecting_oxytocin_to_feel/

There are more posts.

I understand it's also fragile and difficult to recon.

At the risk of oversharing, and perhaps sounding like a sissy, I have some experiences that make me suspect that additional oxytocin could benefit me.

I wasn't close with my mother growing up and she was unable to breastfeed. Me and my dad were very close, until he had a paychotic break after the divorce when I was 13. I went with him and went no-contact with my mother for six years, and felt very intense lonliness for a long time that turned into hardcore drug abuse between the ages of 16 and last year.

I handle breakups the way that other people handle death. Dreams and nightmares and vivid memories that linger for years afterwards. Wailing, crying in my sleep.

When I have the opportunity to be with close friends, which is rare, I initiate a LOT of physical contact – and I honestly wish that sleeping in the same bed with your friends wasn't so stigmatized as a man.

I also exhibit a lot of autistic behaviours. I'm not sure if I always have or if my unique combination of environmental stressors and weird upbringing have caused some kind of functional equivalent. There's a bit of a dichotomy since I can be very outgoing one minute and struggle intensely with eye contact the next.

All this to say that I am a bit of an odd bird, and I often react very differently to substances than my peers do. For instance, benzodiazepines make me euphoric and are incredibly addictive to me, but opiates don't bother me at all. I actually used kratom for a few years for this very reason, and was able to quit the habit practically overnight when I suspected it was no longer serving me.

On an unrelated note, for those still reading, allopregnanolone and Clonidine were recommended and interest me as well.

I understand that Clonidine sort of works in the opposite way that caffeine does, and caffeine makes me very anxious and causes sleep disturbances 16+ hours after dosing.

Sorry for a shitty and weird post. I didn't get into peptides because I was a happy, healthy individual lol.
 
My son has been on clonidine for 20+ years to sleep. He never got past the baby sleep stage. His autism is severe and he's non-verbal. Maybe oxytocin is worth looking into. Maybe even for me too, because of my weird behaviors.
 
cheaperseeker said:
I haven't tried oxytocin yet, but it's on my list.

Anyway, I'm sorry for all the shit you're going through, and I hope you find something that helps soon.
Thank you! Really, I think this is the upswing, reta has been a game changer so far and a recent run in with the law took the fire out of me. I think I might be heading into my thirties with a clear head.

sheilarae74 said:
My son has been on clonidine for 20+ years to sleep. He never got past the baby sleep stage. His autism is severe and he's non-verbal. Maybe oxytocin is worth looking into. Maybe even for me too, because of my weird behaviors.
Glad it works for your son. I mentioned it to my mom and she said it was a popular choice for SLO children as well.

And who knows! Worst case it doesn't work right?
 
I gave oxytocin a try, once. I used the very limited information I had on subcutaneous dosing. First, this has an insanely short half life. I believe it is 6 minutes. Second, dosages were mostly when ROA was nasal spray, but there were a few recommendations for subcutaneous.

I felt okay for a few minutes, then my skin felt warm, then hot. It was like a CJC/IPA flush turned up many many factors. Then I just felt... Sleepy. A little disappointed.

The next say, I felt nauseous, pretty moderate headache, and felt overall down, for the day. Even with stimulants. I did my best to get a decent rest that night, and I felt better the next day. Certainly wasn't for me, but maybe the spray is better.
 
Neurogroot said:
I gave oxytocin a try, once.

Pardon the familiarity, but do you have trouble with eye contact, an abnormal relationship with physical affection, or an unhealthy affinity for any kind of military hardware/civil machinery?
 
I’ve got trouble with eye contact for sure. Not sure if physical contact is abnormal. Just a bit awkward, high affinity for numbers, patterns… All checks out for my DevOps position.
 
Neurogroot said:
I’ve got trouble with eye contact for sure. Not sure if physical contact is abnormal. Just a bit awkward, high affinity for numbers, patterns… All checks out for my DevOps position.
I believed you, and then I heard DevOps and knew it was the truth! Disappointing news, here I was hoping a peptide could possibly fix my head. Guess I have to stick to the body and be thankful for it.
 
birdwhacker said:
I believed you, and then I heard DevOps and knew it was the truth! Disappointing news, here I was hoping a peptide could possibly fix my head. Guess I have to stick to the body and be thankful for it.
The callout for what I was really tickled me a bit. I had to show a coworker because he likes to point out when I spot weird numeric patterns.

Not sure if you’ve tried it, but… N-Acetyl Selank Amidate. I ignored it forever, it just seemed fake, or worthless. The past 3 weeks, I’ve tried it. It’s not overwhelming by any means, but when it sets in, and you think about it 40-some minutes later, you’ll think “Wow, this is pretty nice.”

The counterpart N-Acetyl Semax Amidate is pretty fantastic in morning to fuel my weird weird brain. I could see some people getting anxious on it, it is surprisingly stimulating in a different way from amphetamine or methylphenidate based medications. Helps me, but if you’re easily wired, maybe not.

Important to note, the plain Semax and Selank are okay, but short lived and felt like something was missing. On the other side, Adamax? Underwhelming. To me, at least.

Note: Took all of these, the standard, the N-Acetyl Amidate and Ada versions subcutaneously, not spray.
 
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