On Tirzepatide and Ipamorelin adding Tesamorelin

[Brando123]

Hey there, 40 year old male, 5’10” CW 184 GW 170.

I’m currently taking 7.5mg Tirz every 6 days and 150mcg of ipamorelin every night before bed two hours after dinner as well as 4x a week before morning workout.

I’d like to do a 10-12 week cycle of Tesamorelin to help with body recomp.

Would you suggest 2mg before bed or 1mg in the morning and 1mg before bed 5 days on 2 days off?

 

[Lullabytreehugger]

Try both and see what works best for you. Is it abdominal fat you are worried about? Tbh honest I tried it and so far not much results … tried now for two weeks … their is this other thing called fat dissolving injections

Google Lipo V

 

[hexagonal]

Discussion - Clinical Review Report: Tesamorelin (Egrifta) - NCBI Bookshelf

Studies checked at 6 month and 1 year intervals. Even from a mechanistic standpoint there is no reason to expect any noticeable change at 2 weeks.

 

[Lullabytreehugger]

Discussion - Clinical Review Report: Tesamorelin (Egrifta) - NCBI Bookshelf

Studies checked at 6 month and 1 year intervals. Even from a mechanistic standpoint there is no reason to expect any noticeable change at 2 weeks.

I am finding it does bump up my blood sugars by a bit …

 

[jaestar]

I have read that most don't start seeing results until around eight weeks.

 

[sepehr]

My understanding is that it has to be before night sleep; as it has a longer half life compared to ipamorelin and such. 2mg is too much imho, even though that's the standard FDA dose.

1mg 30-60m before bed, 30-60m after administration of 100mcg Ipamorelin to suppress somatostatin. 3-5d on, 4-2d off depending on individual side effect profile.

See:

[archived internal link]

Post in thread 'Tesa+ipa premixed 10:5'

Dec 5, 2024

I strongly doubt the premixed Tesa 10mg+Ipa 5mg are the effective dose for fat burn and muscle building.

Dr. William Seeds recommended protocol for men and women is:

At night before going to bed:

- 1mg Tesamorelin *(reconstituted as 1ml)*

- plus 100mcg Ipamorelin

First thing in the morning:

- 100mcg Ipamorelin

Notes:

- He suggests to take 1 or 2 day holiday every week (~5days a week).

- For older people, Seeds might choose 50mcg of IPA instead of 100mcg. Individual responses matter.

—

He explicitly mentions taking more than 100mcg of IPA is not effective and is a waste of...

sepehr

Also I'd watch for water retention symptoms while using it. It might affect your sleep negatively if hydration is not taken care of.