Joe Rogan with Brigham Buhler on all things health with focus on peptides

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jungletech said:
Maybe try sema? It seems very good for appetite suppression. I take 1 mg of it and can barely eat.
I may try it. I tried it for a month but I didn't feel anything. I did take tirz for 5 months and went up to 12.5. I might try adding cag or maybe survo.
 
sfkid said:
GLPs are not some "black magic" that makes the weight come off magically. They suppress appetite which SHOULD put you in a caloric deficit which will make your body use the stored fat as energy which will make you lose weight.

if you are not losing any weight, you might not be in a caloric deficit. Maybe you need to move a little more (more steps).

If you are not feeling any appetite suppression then that could be something else (bad batch of reta? / not a hyper responder to GLPs?). Maybe you just need a higher dose and a little time for it to work its way in your body...

How long have you been on Reta?
That's the main issue that I"ve had with GLP's. THey are supposed to help suppress appetite. I was on Tirz for 5 months and up to 12.5. THe day after the first shot at 2.5 , I woke up and and had no appetite. That lasted for 4 days and then NOTHING for the next 5 months. I have been on Reta since last July and was up to 10mg/week in mid-Dec. I was waiting for more stock and was trying to ration what I had so I stayed at 10mg for 2 months and then all of a sudden, I start to get suppression. When my shipment came in I thought about going up more but stayed at 10 up until now and I'm starting to lose that suppression and will have to increase. At some point I"m afraid that it just won't work and I have alot of weight to lose and haven't made much progress. . Since the weather warmed up I have been walking more but that has a tendency to increase my appetite.
 
toologic said:
That's the main issue that I"ve had with GLP's. THey are supposed to help suppress appetite. I was on Tirz for 5 months and up to 12.5. THe day after the first shot at 2.5 , I woke up and and had no appetite. That lasted for 4 days and then NOTHING for the next 5 months. I have been on Reta since last July and was up to 10mg/week in mid-Dec. I was waiting for more stock and was trying to ration what I had so I stayed at 10mg for 2 months and then all of a sudden, I start to get suppression. When my shipment came in I thought about going up more but stayed at 10 up until now and I'm starting to lose that suppression and will have to increase. At some point I"m afraid that it just won't work and I have alot of weight to lose and haven't made much progress. . Since the weather warmed up I have been walking more but that has a tendency to increase my appetite.
Are you doing 10mg once a week? Some benefit by splitting the dose twise weekjly or even more frequently...
 
sfkid said:
Are you doing 10mg once a week? Some benefit by splitting the dose twise weekjly or even more frequently...
I take 5mg twice a week. When I first started I took my dose once a week and about 3 months ago started twice a week. Also when I do exercise, I get hungry and if I don't eat something I get massive sick headaches.
 
toologic said:
I take 5mg twice a week. When I first started I took my dose once a week and about 3 months ago started twice a week. Also when I do exercise, I get hungry and if I don't eat something I get massive sick headaches.
Im not a doctor but that sounds like you have very low blood sugar. Have you done any blood work?

if not, the minimum I do is:

Hemoglobin A1C

Fasting plasma glucose
 
That sucks that some of you are having it not work after a time. I just have medication related hunger that is ravenous, but it seems combatible at normal doses.
 
sfkid said:
Im not a doctor but that sounds like you have very low blood sugar. Have you done any blood work?

if not, the minimum I do is:

Hemoglobin A1C

Fasting plasma glucose
I am going for tests in late April. My last A1c was 5.5 and glucose 100. Not great but still in range. I take berberine before eating and since being on Reta I"ve tried to go off of it but when I eat even a small meal even with nothing but protein/fat, I would would start to fall asleep so I continue using the berberine. I tried using a CGM for a month to try and figure out what my glucose was doing but it was not showing anything out of the ordinary. THe only thing that would bring my glucose into the mid 80's is excercising.
 
His last appearance he complained about big Pharma wanting to come in and take control of peps. This episode he's wanting more regulations as more people are going gray. They both were talking about stem cell therapies and how they need to be here in the US, but talks about sending people to Mexico and Panama to receive them... kinda talking out of both sides of his mouth.
 
toologic said:
I am going for tests in late April. My last A1c was 5.5 and glucose 100. Not great but still in range. I take berberine before eating and since being on Reta I"ve tried to go off of it but when I eat even a small meal even with nothing but protein/fat, I would would start to fall asleep so I continue using the berberine. I tried using a CGM for a month to try and figure out what my glucose was doing but it was not showing anything out of the ordinary. THe only thing that would bring my glucose into the mid 80's is excercising.
You're pre-diabetic based upon your A1c and fasting glucose. By the time those numbers reflect the issue you've been developing the condition for some time. Are you taking a GLP?
 
tendency said:
You're pre-diabetic based upon your A1c and fasting glucose. By the time those numbers reflect the issue you've been developing the condition for some time. Are you taking a GLP?
yes. Tirz did nothing and Reta has helped my heart more than anything. Little weightloss on either of these two
 
Really good podcast with Rogan and Brigham Buhler, was definitely worth a listen. They’d rather treat the symptom then the cause…..
 
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