IGF-1 LR3 - not seeing much talk here

[Calm Logic]

On that note, some men are doing subq and don't even know it:

Previous data that used imaging (computed tomography or ultrasound) to estimate SC fat thickness and compared it with the length of the needle (or placement of the injectate) estimated that 12% to 85% of IM injections administered to men were actually SC ( 31-33 ).

Indeed, this might explain the observation that IM injections are less painful in overweight and obese men ( 34 ).

from Testosterone Therapy With Subcutaneous Injections: A Safe, Practical, and Reasonable Option

But if you have to use IM due to ISR issues with the carrier oil or volume, then the VG (ventrogluteal) muscle area, previously mentioned by @zpped for deep subq, is my favorite IM location. A nurse on YouTube known as Nurse Scott has a great video on IM for VG.

"The ventrogluteal site is one of the preferred and safest locations for IM injections because it has a thick muscle mass and is far from major nerves and blood vessels." (Google Gemini)

 

[LeeBruce]

I have used IGFLR3 and did not see or feel any benefit , as a serious BB/weightlifter for 40 years I have seen the new peps and supps/drugs come and go . In the bodybuilding world almost all experienced people stick to HGH some all year round especially ones on TRT as its now cheaper daily than buying a beer . GLP1s have changed the world . Some things look good on paper when you are doing research like frag 176-191which was billed as the purified fat burning quality's of HGH which I spent money on years ago but did not see any results . I now use 4iu hgh a day 200mg test and retatrutide 5mg a week all year round and I find it consistently effective tolerable and bloods are good . I don't recommend IGF des or lr3 you will always find someone using it getting hit by the hype placebo an swearing by it . But In the world I have been in for 40 years no one does there all on Chinese HGH because it consistently works

 

[Dogmandu]

I know basically nothing about HGH, IGF-1 or anything along those lines, but what I do find fascinating that's been brought up here is how a lot of conventional wisdom regarding injecting IM or SC seems to be under renewed scrutiny. A buddy who has been on TRT for many years recently changed to SC and hasn't stopped preaching about it being superior in every way. Not sure if there's any validity to that, but interesting nonetheless.

I made the switch from IM to SubQ on TRT about 2 months ago after listening to Derek Munro (MPMD) on Peter Attia podcast. I LOVE subQ. Wish I'd known sooner that it was an option.

 

[Jellybelly54]

I don’t know of anything better for weight than GLPs. I think HGH is more to the point than any of the secretagogues and the niche peptides like AOD, 5-Amino. I think it’s the best for anti-aging as well but if you are under 40 you probably produce enough GH on your own. The only peptides I have faith in are GLPs, Glutathione and AICAR. I’ve tried more at this point than I haven’t but everyone is different.

How did you dose AICAR and what do you notice on a cycle of it? I’m like you, tried more than I haven’t and noticed little on most peps. Nootropics don’t do anything for me. GHRH/GHRP …nothing. Looking at my next cycle and considering Cortagen versus cerebrolysin , AICAR and maybe testagen . Thoughts?

 

[AndyPanda]

How did you dose AICAR and what do you notice on a cycle of it? I’m like you, tried more than I haven’t and noticed little on most peps. Nootropics don’t do anything for me. GHRH/GHRP …nothing. Looking at my next cycle and considering Cortagen versus cerebrolysin , AICAR and maybe testagen . Thoughts?

What I physically notice with AICAR is breaking weight loss plateau, endurance, and anti-inflammatory benefits. Cycle 25mg daily for 2 weeks. Twice per year. I don’t know enough about the others mentioned to speak intelligently about them. I’ve been looking for a source for legitimate pharma grade cerebrolysin..

 

[latviantower]

What I physically notice with AICAR is breaking weight loss plateau, endurance, and anti-inflammatory benefits. Cycle 25mg daily for 2 weeks. Twice per year. I don’t know enough about the others mentioned to speak intelligently about them. I’ve been looking for a source for legitimate pharma grade cerebrolysin..

JTP may have a few 5 vial kits of Altra Pure left - he was clearing them out. Otherwise Nootropics Base (Russia) producing Cerebro under license from EverPharm (Austria).

 

[Jellybelly54]

What is the cerebrolysin lypholized stuff most

Of the CN pep dealers sell? Obviously it’s not the real deal but what’s in it I wonder?

 

[yrrdead]

What is the cerebrolysin lypholized stuff most

Of the CN pep dealers sell? Obviously it’s not the real deal but what’s in it I wonder?

I believe that it is cerebroprotein hydrolysate but that apparently covers a wider category of chemicals. Most are not the same formula as name brand Cerebrolysin.

But this study ; https://pmc.ncbi.nlm.nih.gov/articles/PMC10154667/

uses Heimerkang Brain Polypeptide from a company in China.

How many different ones of these are there? From which animals? And are they all effective? Who knows.