How to switch from TIRZ to RETA without losing progress?

[70707]

Been on Tirz since January '26 and have lost around 12kgs since. Taking it easy with dosage and currently at 5mg weekly or 7.5mg whenever I feel like I need that extra push. I am looking to make the switch to Reta but do not know how to approach this without losing any of the progress made.

I took my usual 5mg of TIRZ at the beginning of this week, and then took 2mg of RETA today with the idea of getting my body accustomed.

Where should I go from here?

How did you, the wise people of the forum, handle the switch?

 

[MFGamesta]

I switched cold turkey. 2.5 tirzapatide to 2mg reta r next week. With the 7 day half life, it was perfect.

 

[70707]

I switched cold turkey. 2.5 tirzapatide to 2mg reta r next week. With the 7 day half life, it was perfect.

The dose of TIRZ you were on probably made it easier for you to just replace it with practically the same amount of reta.

Did it affect food noise and general interest in food?

 

[MFGamesta]

There was a little bit more food noise but the reta burned more fat and my goal was to lose weight. I didn't want to be chasing a food suppression high.

 

[woundcarping]

Been on Tirz since January '26 and have lost around 12kgs since. Taking it easy with dosage and currently at 5mg weekly or 7.5mg whenever I feel like I need that extra push. I am looking to make the switch to Reta but do not know how to approach this without losing any of the progress made.

I took my usual 5mg of TIRZ at the beginning of this week, and then took 2mg of RETA today with the idea of getting my body accustomed.

Where should I go from here?

How did you, the wise people of the forum, handle the switch?

I went from 5mg of Tirz to Reta back in January. I've made numerous posts about the way I did it and the resultant data.

 

[janedoe]

I posted this on here somewhere previously

Been in maintenance since May 2025.

I did not not wash out and pretty much went off Tirz cold.

On Tirz exactly 1 year almost to the day ( May 30th 2025 I believe was my last day). I maxed at 15mg for 5 months. ( roughly January 2025- May 2025.) The bulk of my weight was lost from May 2024 thru December 2024, when I went from 12.5 to 15). My last 20lbs to hit my goal was when I went to 15mg Tirz. In the last 2 weeks of my Tirz use, I dropped to 10mg and implemented .125 cagri. I then dropped the Tirz all together the next week, began 1mg Reta and with .25 Cagri for maintenance ( no wash out, though I considered it).

Still at goal, at 3mg Reta alone. Dropped Cagri November 2025. I inadvertently lost roughly 15 more lbs during maintenance, which is why I stopped the Reta/ Cagri stack. Still at Reta 3mg 1x per week protocol for maintenance( 1 year maintenance this month). Weight stable, and I can enjoy food.