Cresol, anyone?

[Chili777]

It was recently found on STG that a vendor's mazdutide contained cresol, a highly toxic antiseptic. The only way that could have got in there is during the manufacturing process. It's not used in the lyophilizing process as there is no cresol (or metacresol) listed in the inactive ingredients.The excipients used in the lyophilization process are:

· Trometamol

· Mannitol

· Propylene glycol (for injection)

· Disodium edetate

· Dilute hydrochloric acid

· Sodium hydroxide

· Water for injections

None of these are or contain cresol.

Comments:

"There should never be enough cresol to have a lab put this on a coa

Sry had it one time and gave out refunds

But this isn’t normal

You should get a refund if this is in your peps

This is trash pep

Do not use this throw it only"

Old timers may remember last year when SRY had this issue (along with Paraben) and refunds were given.

Let's be careful out there people.

 

[CandyCap]

It was recently found on STG that a vendor's mazdutide contained cresol, a highly toxic antiseptic. The only way that could have got in there is during the manufacturing process. It's not used in the lyophilizing process as there is no cresol (or metacresol) listed in the inactive ingredients.The excipients used in the lyophilization process are:

· Trometamol

· Mannitol

· Propylene glycol (for injection)

· Disodium edetate

· Dilute hydrochloric acid

· Sodium hydroxide

· Water for injections

None of these are or contain cresol.

Comments:

"There should never be enough cresol to have a lab put this on a coa

Sry had it one time and gave out refunds

But this isn’t normal

You should get a refund if this is in your peps

This is trash pep

Do not use this throw it only"

Old timers may remember last year when SRY had this issue (along with Paraben) and refunds were given.

Let's be careful out there people

I believe Jano replied saying this was a common preservative used in insulin, if I am not mistaken.

 

[Habibibi]

Not all cresol is toxic. The report was updated to contain m-cresol, which is used as a preservative.

 

[Chili777]

Not all cresol is toxic. The report was updated to contain m-cresol, which is used as a preservative.

Where is the update? I don't see Peter chiming in either chat on STG.

m-Cresol - Hazardous Agents | Haz-Map

m-Cresol agent detailed information in Haz-Map database.

www.haz-map.com

 

[sheilarae74]

Jesus, they use that stuff as a dip to de-flea barnyard animals and on railroad ties.

 

[Habibibi]

Where is the update? I don't see Peter chiming in either chat on STG.

m-Cresol - Hazardous Agents | Haz-Map

m-Cresol agent detailed information in Haz-Map database.

www.haz-map.com

Look at the COA again

(link deleted since COA is from a gb )

M-cresol is fine in concentrations of 3-4mg/ml or less.

 

[Chili777]

Look at the COA again

(link deleted since COA is from a gb )

M-cresol is fine in concentrations of 3-4mg/ml or less.

From Meso in Analytical Lab Testing thread on Cresol, see attached. It's a poor choice for preservation, especially for GLPs. Insulin is not a GLP.

Also, Peter's comment doesn't pass judgement on whether it's good or bad, just that it's there. The peak also doesn't indicate volume because that test doesn't provide that. His comment on the test says it's also not counted among the impurities. Just like his Jeep endo test that just said 2306EU. He let others draw conclusions as to whether that was bad or not, and most drew the correct conclusion.

 

[Habibibi]

From Meso in Analytical Lab Testing thread on Cresol, see attached. It's a poor choice for preservation, especially for GLPs.

Also, Peter's comment doesn't pass judgement on whether it's good or bad, just that it's there. The peak also doesn't indicate volume because that test doesn't provide that. Just like his Jeep endo test that just said 2306EU. He let others draw conclusions as to whether that was bad or not, and most drew the correct conclusion.

Your screenshot seems to make my point as it says that in multipens they use M-cresol or phenol...

It shouldn't be there anyway, but it's not automatically poison (depending on the dose) .

 

[Chili777]

Your screenshot seems to make my point as it says that in multipens they use M-cresol or phenol...

It shouldn't be there anyway, but it's not automatically poison (depending on the dose) .

Yes, for reconstituted GLPs, I read that 0.2% is allowable. There is no reason for it to be in any lysophilized peptides in any quantity.